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Control of misincorporation of serine for asparagine during antibody production using CHO cells

Biotechnology and bioengineering, 2010-09, Vol.107 (1), p.116-123

2010

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Discovery and Investigation of Misincorporation of Serine at Asparagine Positions in Recombinant Proteins Expressed in Chinese Hamster Ovary Cells

The Journal of biological chemistry, 2009-11, Vol.284 (47), p.32686-32694

2009

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Selectivity of BAFF/BLyS and APRIL for Binding to the TNF Family Receptors BAFFR/BR3 and BCMA

Biochemistry (Easton), 2005-02, Vol.44 (6), p.1919-1931

2005

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Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog

The Journal of biological chemistry, 1998-05, Vol.273 (22), p.14037-14045

1998

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Growth Factor Induction of Cripto-1 Shedding by Glycosylphosphatidylinositol-Phospholipase D and Enhancement of Endothelial Cell Migration

The Journal of biological chemistry, 2007-10, Vol.282 (43), p.31643-31655

2007

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Distinguishing between Leucine and Isoleucine by Integrated LC–MS Analysis Using an Orbitrap Fusion Mass Spectrometer

Analytical chemistry (Washington), 2016-11, Vol.88 (21), p.10757-10766

2016

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Production of a PEGylated Fab′ of the anti-LINGO-1 Li33 Antibody and Assessment of Its Biochemical and Functional Properties in Vitro and in a Rat Model of Remyelination

Bioconjugate chemistry, 2011-02, Vol.22 (2), p.200-210

2011

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Identification and Sequencing of N‑Terminal Peptides in Proteins by LC-Fluorescence-MS/MS: An Approach to Replacement of the Edman Degradation

Analytical chemistry (Washington), 2019-11, Vol.91 (21), p.13591-13600

2019

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Design, Synthesis, and Structure−Activity Relationships of Haloenol Lactones: Site-Directed and Isozyme-Selective Glutathione S-Transferase Inhibitors

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.3282-3294

2004

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Resolution of disulfide heterogeneity in Nogo receptor I fusion proteins by molecular engineering

Biotechnology and applied biochemistry, 2010-09, Vol.57 (1), p.31-45

2010

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A Prodomain Fragment from the Proteolytic Activation of Growth Differentiation Factor 11 Remains Associated with the Mature Growth Factor and Keeps It Soluble

Biochemistry (Easton), 2017-08, Vol.56 (33), p.4405-4418

2017

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Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Journal of pharmaceutical sciences, 2002-02, Vol.91 (2), p.371-387

2002

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Characterization of trisulfide modification in antibodies

Analytical biochemistry, 2010-05, Vol.400 (1), p.89-98

2010

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Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC–MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments

Analytical chemistry (Washington), 2017-04, Vol.89 (7), p.4021-4030

2017

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Discovery and Investigation of O‑Xylosylation in Engineered Proteins Containing a (GGGGS) n Linker

Analytical chemistry (Washington), 2013-05, Vol.85 (9), p.4805-4812

2013

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EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies

mAbs, 2018-11, Vol.10 (8), p.1248-1259

2018

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Mechanistic studies of inactivation of glutathione S-transferase Pi isozyme by a haloenol lactone derivative

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2005-03, Vol.1 (2), p.191

2005

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Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications

Protein expression and purification, 2003-06, Vol.29 (2), p.272-283

2003

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Discovery and Investigation of O-Xylosylation in Engineered Proteins Containing a (GGGGS)^sub n^ Linker

Analytical chemistry (Washington), 2013-05, Vol.85 (9), p.4805

2013

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Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation

Analytical biochemistry, 2008-06, Vol.377 (1), p.95-104

2008

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N-Terminally PEGylated Human Interferon-β-1a with Improved Pharmacokinetic Properties and in Vivo Efficacy in a Melanoma Angiogenesis Model

Bioconjugate chemistry, 2006-01, Vol.17 (1), p.179-188

2006

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The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small‐molecule inhibitor

Acta crystallographica. Section F, Structural biology communications, 2020-03, Vol.76 (3), p.103-108

2020

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Structure-function relationships in an antifreeze polypeptide. The role of neutral, polar amino acids

The Journal of biological chemistry, 1992-07, Vol.267 (20), p.14102-14108

1992

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N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model

Bioconjugate chemistry, 2006-01, Vol.17 (1), p.179-188

2006

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Engineering potent long-acting variants of the Wnt inhibitor DKK2

Protein engineering, design and selection, 2017-05, Vol.30 (5), p.359-372

2017

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Control of misincorporation of serine for asparagine during antibody production using CHO cells

Discovery and Investigation of Misincorporation of Serine at Asparagine Positions in Recombinant Proteins Expressed in Chinese Hamster Ovary Cells

Selectivity of BAFF/BLyS and APRIL for Binding to the TNF Family Receptors BAFFR/BR3 and BCMA

Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog

Growth Factor Induction of Cripto-1 Shedding by Glycosylphosphatidylinositol-Phospholipase D and Enhancement of Endothelial Cell Migration

Distinguishing between Leucine and Isoleucine by Integrated LC–MS Analysis Using an Orbitrap Fusion Mass Spectrometer

Production of a PEGylated Fab′ of the anti-LINGO-1 Li33 Antibody and Assessment of Its Biochemical and Functional Properties in Vitro and in a Rat Model of Remyelination

Identification and Sequencing of N‑Terminal Peptides in Proteins by LC-Fluorescence-MS/MS: An Approach to Replacement of the Edman Degradation

Design, Synthesis, and Structure−Activity Relationships of Haloenol Lactones: Site-Directed and Isozyme-Selective Glutathione S-Transferase Inhibitors

Resolution of disulfide heterogeneity in Nogo receptor I fusion proteins by molecular engineering

A Prodomain Fragment from the Proteolytic Activation of Growth Differentiation Factor 11 Remains Associated with the Mature Growth Factor and Keeps It Soluble

Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Characterization of trisulfide modification in antibodies

Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC–MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments

Discovery and Investigation of O‑Xylosylation in Engineered Proteins Containing a (GGGGS) n Linker

EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies

Mechanistic studies of inactivation of glutathione S-transferase Pi isozyme by a haloenol lactone derivative

Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications

Discovery and Investigation of O-Xylosylation in Engineered Proteins Containing a (GGGGS)^sub n^ Linker

Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation

N-Terminally PEGylated Human Interferon-β-1a with Improved Pharmacokinetic Properties and in Vivo Efficacy in a Melanoma Angiogenesis Model

The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small‐molecule inhibitor

Structure-function relationships in an antifreeze polypeptide. The role of neutral, polar amino acids

N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model

Engineering potent long-acting variants of the Wnt inhibitor DKK2

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