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Spotlight on gene therapy in China

Gene therapy, 2020-08, Vol.27 (7-8), p.307-308

Ding, Qiurong

2020

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In Vivo AAV-CRISPR/Cas9–Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia

Circulation (New York, N.Y.), 2020-01, Vol.141 (1), p.67-79

2020

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Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing

Cell stem cell, 2014-07, Vol.15 (1), p.27-30

2014

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RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

Cell death and differentiation, 2021-04, Vol.28 (4), p.1418-1433

2021

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Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells

Pflügers Archiv, 2021-07, Vol.473 (7), p.991-1007

2021

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Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis

Nature communications, 2019-09, Vol.10 (1), p.4158-15, Article 4158

2019

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Genome engineering of stem cell organoids for disease modeling

Protein & cell, 2017-05, Vol.8 (5), p.315-327

2017

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A Self-restricted CRISPR System to Reduce Off-target Effects

Molecular therapy, 2016-09, Vol.24 (9), p.1508-1510

2016

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Type 2 Diabetes Variants in the SLC16A11 Coding Region Are Not Loss-of-Function Mutations

Cell reports (Cambridge), 2019-10, Vol.29 (3), p.781-784

2019

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Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice

Nature communications, 2023-03, Vol.14 (1), p.1521-1521, Article 1521

2023

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Optimized protocols for efficient gene editing in mouse hepatocytes in vivo using CRISPR-Cas9 technology

STAR protocols, 2022-03, Vol.3 (1), p.101062-101062, Article 101062

2022

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BACH1 controls hepatic insulin signaling and glucose homeostasis in mice

Nature communications, 2023-12, Vol.14 (1), p.8428-8428, Article 8428

2023

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Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

The Journal of clinical investigation, 2012-08, Vol.122 (8), p.2807-2816

2012

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Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology

STAR protocols, 2021-03, Vol.2 (1), p.100307-100307, Article 100307

2021

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Cas9-nickase–mediated genome editing corrects hereditary tyrosinemia in rats

The Journal of biological chemistry, 2018-05, Vol.293 (18), p.6883-6892

2018

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Dietary Fat Intake and Risk of Gastric Cancer: A Meta-Analysis of Observational Studies

PloS one, 2015-09, Vol.10 (9), p.e0138580-e0138580

2015

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Modeling drug-induced liver injury and screening for anti-hepatofibrotic compounds using human PSC-derived organoids

Cell regeneration, 2023-03, Vol.12 (1), p.6-6, Article 6

2023

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NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143

Cell communication and signaling, 2022-06, Vol.20 (1), p.87-87, Article 87

2022

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Identification of small-molecule ion channel modulators in C. elegans channelopathy models

Nature communications, 2018-09, Vol.9 (1), p.3941-12, Article 3941

2018

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Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer

International journal of oncology, 2016-01, Vol.48 (1), p.215-224

2016

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Genome-scale CRISPR screening for potential targets of ginsenoside compound K

Cell death & disease, 2020-01, Vol.11 (1), p.39-39, Article 39

2020

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Single-cell sequencing unveils key contributions of immune cell populations in cancer-associated adipose wasting

Cell discovery, 2022-11, Vol.8 (1), p.122-122, Article 122

2022

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Spatial regulation of Raf kinase signaling by RKTG

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (36), p.14348-14353

2007

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Liver in a dish

Cell research, 2013-11, Vol.23 (11), p.1242-1243

2013

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Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells

Stem cell reports, 2018-07, Vol.11 (1), p.22-31

2018

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Spotlight on gene therapy in China

In Vivo AAV-CRISPR/Cas9–Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia

Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing

RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells

Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis

Genome engineering of stem cell organoids for disease modeling

A Self-restricted CRISPR System to Reduce Off-target Effects

Type 2 Diabetes Variants in the SLC16A11 Coding Region Are Not Loss-of-Function Mutations

Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice

Optimized protocols for efficient gene editing in mouse hepatocytes in vivo using CRISPR-Cas9 technology

BACH1 controls hepatic insulin signaling and glucose homeostasis in mice

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology

Cas9-nickase–mediated genome editing corrects hereditary tyrosinemia in rats

Dietary Fat Intake and Risk of Gastric Cancer: A Meta-Analysis of Observational Studies

Modeling drug-induced liver injury and screening for anti-hepatofibrotic compounds using human PSC-derived organoids

NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143

Identification of small-molecule ion channel modulators in C. elegans channelopathy models

Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer

Genome-scale CRISPR screening for potential targets of ginsenoside compound K

Single-cell sequencing unveils key contributions of immune cell populations in cancer-associated adipose wasting

Spatial regulation of Raf kinase signaling by RKTG

Liver in a dish

Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells

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