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Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model

British journal of anaesthesia : BJA, 2009-03, Vol.102 (3), p.345-354

2009

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Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model

Journal of thrombosis and haemostasis, 2012-09, Vol.10 (9), p.1841-1848

2012

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Four‐factor prothrombin complex concentrate reverses apixaban‐associated bleeding in a rabbit model of acute hemorrhage

Journal of thrombosis and haemostasis, 2015-12, Vol.13 (12), p.2220-2226

2015

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Pharmacological characteristics of a novel, recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa‐FP)

Journal of thrombosis and haemostasis, 2014-02, Vol.12 (2), p.220-228

2014

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Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model

British journal of anaesthesia : BJA, 2010-11, Vol.105 (5), p.576-582

2010

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Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence?

Thrombosis and haemostasis, 2014-02, Vol.111 (2), p.189-198

2014

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Improved kinetics of rIX‐FP, a recombinant fusion protein linking factor IX with albumin, in cynomolgus monkeys and hemophilia B dogs

Journal of thrombosis and haemostasis, 2012-08, Vol.10 (8), p.1591-1599

2012

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Repeated infusions of VWF/FVIII concentrate: impact of VWF:FVIII ratio on FVIII trough and peak levels in a rabbit model

Haemophilia : the official journal of the World Federation of Hemophilia, 2011-09, Vol.17 (5), p.808-814

2011

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A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk

Science translational medicine, 2014-02, Vol.6 (222), p.222ra17

2014

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Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense

Blood, 2011-09, Vol.118 (9), p.2589-2598

2011

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Treatment of porcine sepsis with high-dose antithrombin III reduces tissue edema and effusion but does not increase risk for bleeding

Blood coagulation & fibrinolysis, 2001-09, Vol.12 (6), p.459-467

2001

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Prevention of Gynaecological Adhesions using Haemostatic Fleece in a Rabbit Model

Journal of international medical research, 2006-09, Vol.34 (5), p.505-513

2006

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Four-factor prothrombin complex concentrate (Beriplex® P/N) is superior to three-factor prothrombin complex concentrate for reversal of coumarin anticoagulation

Critical care (London, England), 2015-01, Vol.19 (S1), p.P347-P347, Article P347

2015

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C1-esterase inhibitor treatment: preclinical safety aspects on the potential prothrombotic risk

Thrombosis and haemostasis, 2014-11, Vol.112 (5), p.960-971

2014

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Local activation of coagulation factor XIII reduces systemic complications and improves the survival of mice after Streptococcus pyogenes M1 skin infection

International journal of medical microbiology, 2016-11, Vol.306 (7), p.572-579

2016

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Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction

Circulation (New York, N.Y.), 2006-03, Vol.113 (9), p.1196-1202

2006

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Four-factor prothrombin complex concentrate (Beriplex® P/N) mediated reversal of apixaban-induced bleeding in a rabbit model

Critical care (London, England), 2015-01, Vol.19 (S1), p.P348-P348, Article P348

2015

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Comparison of prothrombin complex concentrate and fresh frozen plasma on thrombin generation and hemorrhage in experimental dilutional coagulopathy

Critical care (London, England), 2008, Vol.12 (Suppl 2), p.P225-P225

2008

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Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages

Blood, 2003-12, Vol.102 (13), p.4410-4412

2003

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Antithrombin III in Animal Models of Sepsis and Organ Failure

Seminars in thrombosis and hemostasis, 1998-01, Vol.24 (1), p.61-69

Dickneite, Gerhard

1998

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Reduction of mortality with antithrombin III in septicemic rats: a study of Klebsiella pneumoniae induced sepsis

Thrombosis and haemostasis, 1993-02, Vol.69 (2), p.98-102

1993

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HAEMODYNAMIC CHANGES UNDER POSITIONING THERAPY IN A PORCINE MODEL

Critical care medicine, 1999-12, Vol.27 (Supplement), p.A129

1999

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Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis

Gut, 1997-04, Vol.40 (4), p.531-535

1997

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Reversal of edoxaban-induced anticoagulation by the four-factor prothrombin complex concentrate Beriplex® in a rabbit model

Critical care (London, England), 2014-03, Vol.18 (2), p.P98-P98, Article P98

2014

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Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit

Thrombosis and haemostasis, 2002-12, Vol.88 (6), p.967-974

2002

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Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model

Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model

Four‐factor prothrombin complex concentrate reverses apixaban‐associated bleeding in a rabbit model of acute hemorrhage

Pharmacological characteristics of a novel, recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa‐FP)

Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model

Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence?

Improved kinetics of rIX‐FP, a recombinant fusion protein linking factor IX with albumin, in cynomolgus monkeys and hemophilia B dogs

Repeated infusions of VWF/FVIII concentrate: impact of VWF:FVIII ratio on FVIII trough and peak levels in a rabbit model

A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk

Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense

Treatment of porcine sepsis with high-dose antithrombin III reduces tissue edema and effusion but does not increase risk for bleeding

Prevention of Gynaecological Adhesions using Haemostatic Fleece in a Rabbit Model

Four-factor prothrombin complex concentrate (Beriplex® P/N) is superior to three-factor prothrombin complex concentrate for reversal of coumarin anticoagulation

C1-esterase inhibitor treatment: preclinical safety aspects on the potential prothrombotic risk

Local activation of coagulation factor XIII reduces systemic complications and improves the survival of mice after Streptococcus pyogenes M1 skin infection

Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction

Four-factor prothrombin complex concentrate (Beriplex® P/N) mediated reversal of apixaban-induced bleeding in a rabbit model

Comparison of prothrombin complex concentrate and fresh frozen plasma on thrombin generation and hemorrhage in experimental dilutional coagulopathy

Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages

Antithrombin III in Animal Models of Sepsis and Organ Failure

Reduction of mortality with antithrombin III in septicemic rats: a study of Klebsiella pneumoniae induced sepsis

HAEMODYNAMIC CHANGES UNDER POSITIONING THERAPY IN A PORCINE MODEL

Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis

Reversal of edoxaban-induced anticoagulation by the four-factor prothrombin complex concentrate Beriplex® in a rabbit model

Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit

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