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Hypoxia as a therapy for mitochondrial disease

Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6281), p.54-61

2016

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High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons

Nature neuroscience, 2011-06, Vol.14 (7), p.911-918

2011

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Adipocyte-Specific Glucocorticoid Inactivation Protects Against Diet-Induced Obesity

Diabetes (New York, N.Y.), 2005-04, Vol.54 (4), p.1023-1031

2005

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PACAP Neurons in the Hypothalamic Ventromedial Nucleus Are Targets of Central Leptin Signaling

The Journal of neuroscience, 2009-11, Vol.29 (47), p.14828-14835

2009

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Selective Inactivation of Socs3 in SF1 Neurons Improves Glucose Homeostasis without Affecting Body Weight

Endocrinology (Philadelphia), 2008-11, Vol.149 (11), p.5654-5661

2008

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PI3K Signaling in the Ventromedial Hypothalamic Nucleus Is Required for Normal Energy Homeostasis

Cell metabolism, 2010-07, Vol.12 (1), p.88-95

2010

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Preliminary Results of a Phase-2 Clinical Trial of the ALK-2 Inhibitor Ker-047 for Treatment of Iron Refractory Iron Deficiency Anemia

Blood, 2022-11, Vol.140 (Supplement 1), p.2475-2476

2022

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Effects of Ker-050 on Iron Metabolism: Exploratory Analyses from an Ongoing Phase 2 Study in Patients with Myelodysplastic Syndromes

Blood, 2022-11, Vol.140 (Supplement 1), p.8181-8183

2022

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Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods

Peptides (New York, N.Y. : 1980), 2002-05, Vol.23 (5), p.975-984

2002

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Leptin Directly Activates SF1 Neurons in the VMH, and This Action by Leptin Is Required for Normal Body-Weight Homeostasis

Neuron (Cambridge, Mass.), 2006-01, Vol.49 (2), p.191-203

2006

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A Phase 2, Open-Label, Ascending Dose Study of Ker-050 for the Treatment of Anemia in Patients with Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Blood, 2021-11, Vol.138 (Supplement 1), p.3675-3675

2021

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Synaptic Glutamate Release by Ventromedial Hypothalamic Neurons Is Part of the Neurocircuitry that Prevents Hypoglycemia

Cell metabolism, 2007-05, Vol.5 (5), p.383-393

2007

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βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5582), p.843-845

2002

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Central Leptin Gene Therapy Blocks High-Fat Diet-Induced Weight Gain, Hyperleptinemia, and Hyperinsulinemia

Diabetes (New York, N.Y.), 2002-06, Vol.51 (6), p.1729-1736

2002

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Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia increase in serum ghrelin levels

Diabetes (New York, N.Y.), 2002-06, Vol.51 (6), p.1729-1736

2002

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Dose-Dependent Effects of Central Leptin Gene Therapy on Genes That Regulate Body Weight and Appetite in the Hypothalamus

Molecular therapy, 2001-08, Vol.4 (2), p.139-145

2001

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The Metabolic and Cardiovascular Effects of Hyperthyroidism Are Largely Independent of β-Adrenergic Stimulation

Endocrinology (Philadelphia), 2004-06, Vol.145 (6), p.2767-2774

2004

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(beta)AR signaling required for diet-induced thermogenesis and obesity resistance

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5582), p.843-845

2002

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βAR signaling required for diet-induced thermogenesis and obesity resistance

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5582), p.f

2002

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Effects of recombinant adeno -associated virus encoding leptin on body weight regulation and energy homeostasis

Dhillon, Harveen

2000

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Induction of PGHS-2 mRNA in response to cerebral hypoperfusion in late-gestation fetal sheep

Prostaglandins & other lipid mediators, 2000-07, Vol.62 (2), p.165-172

2000

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The Estradiol-Induced Luteinizing Hormone Surge in the Ewe is not Associated with Increased Gonadotropin-Releasing Hormone Messenger Ribonucleic Acid Levels1

Biology of reproduction, 1997-07, Vol.57 (1), p.107-111

1997

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The estradiol-induced luteinizing hormone surge in the ewe is not associated with increased gonadotropin-releasing hormone messenger ribonucleic acid levels

Biology of reproduction, 1997-07, Vol.57 (1), p.107-111

1997

Volltextzugriff (PDF)

betaAR signaling required for diet-induced thermogenesis and obesity resistance

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5582), p.843-845

2002

Volltextzugriff (PDF)

A Systems-based Approach to Reduce Deep Venous Thrombosis and Pulmonary Embolism in Trauma Patients

World journal of surgery, 2021-03, Vol.45 (3), p.738-745

2021

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Hypoxia as a therapy for mitochondrial disease

High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons

Adipocyte-Specific Glucocorticoid Inactivation Protects Against Diet-Induced Obesity

PACAP Neurons in the Hypothalamic Ventromedial Nucleus Are Targets of Central Leptin Signaling

Selective Inactivation of Socs3 in SF1 Neurons Improves Glucose Homeostasis without Affecting Body Weight

PI3K Signaling in the Ventromedial Hypothalamic Nucleus Is Required for Normal Energy Homeostasis

Preliminary Results of a Phase-2 Clinical Trial of the ALK-2 Inhibitor Ker-047 for Treatment of Iron Refractory Iron Deficiency Anemia

Effects of Ker-050 on Iron Metabolism: Exploratory Analyses from an Ongoing Phase 2 Study in Patients with Myelodysplastic Syndromes

Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods

Leptin Directly Activates SF1 Neurons in the VMH, and This Action by Leptin Is Required for Normal Body-Weight Homeostasis

A Phase 2, Open-Label, Ascending Dose Study of Ker-050 for the Treatment of Anemia in Patients with Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Synaptic Glutamate Release by Ventromedial Hypothalamic Neurons Is Part of the Neurocircuitry that Prevents Hypoglycemia

βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance

Central Leptin Gene Therapy Blocks High-Fat Diet-Induced Weight Gain, Hyperleptinemia, and Hyperinsulinemia

Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia increase in serum ghrelin levels

Dose-Dependent Effects of Central Leptin Gene Therapy on Genes That Regulate Body Weight and Appetite in the Hypothalamus

The Metabolic and Cardiovascular Effects of Hyperthyroidism Are Largely Independent of β-Adrenergic Stimulation

(beta)AR signaling required for diet-induced thermogenesis and obesity resistance

βAR signaling required for diet-induced thermogenesis and obesity resistance

Effects of recombinant adeno -associated virus encoding leptin on body weight regulation and energy homeostasis

Induction of PGHS-2 mRNA in response to cerebral hypoperfusion in late-gestation fetal sheep

The Estradiol-Induced Luteinizing Hormone Surge in the Ewe is not Associated with Increased Gonadotropin-Releasing Hormone Messenger Ribonucleic Acid Levels1

The estradiol-induced luteinizing hormone surge in the ewe is not associated with increased gonadotropin-releasing hormone messenger ribonucleic acid levels

betaAR signaling required for diet-induced thermogenesis and obesity resistance

A Systems-based Approach to Reduce Deep Venous Thrombosis and Pulmonary Embolism in Trauma Patients

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