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iTeos Therapeutics

Human vaccines & immunotherapeutics, 2017-08, Vol.13 (8), p.1736-1737

Detheux, Michel

2017

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Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation

The Journal of biological chemistry, 2003-07, Vol.278 (28), p.25481-25489

2003

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Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids

The Journal of experimental medicine, 2003-10, Vol.198 (7), p.977-985

2003

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The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54

The Journal of biological chemistry, 2001-09, Vol.276 (37), p.34631-34636

2001

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Identification of a Novel Human ADP Receptor Coupled to Gi

The Journal of biological chemistry, 2001-11, Vol.276 (44), p.41479-41485

2001

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Vasopressin-like peptide and its receptor function in an indirect diuretic signaling pathway in the red flour beetle

Insect biochemistry and molecular biology, 2008-07, Vol.38 (7), p.740-748

2008

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Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties

Blood, 2001-12, Vol.98 (13), p.3554-3561

2001

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Identification and characterization of an endogenous chemotactic ligand specific for FPRL2

The Journal of experimental medicine, 2005-01, Vol.201 (1), p.83-93

2005

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Identification of Natural Ligands for the Orphan G Protein-coupled Receptors GPR7 and GPR8

The Journal of biological chemistry, 2003-01, Vol.278 (2), p.776-783

2003

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Pharmacological characterization of human NPFF1 and NPFF2 receptors expressed in CHO cells by using NPY Y1 receptor antagonists

European journal of pharmacology, 2002-09, Vol.451 (3), p.245-256

2002

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The Orexin OX1 Receptor Activates a Novel Ca2+ Influx Pathway Necessary for Coupling to Phospholipase C

The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30806-30812

2000

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Functional characterization of a human receptor for neuropeptide FF and related peptides

British journal of pharmacology, 2001-05, Vol.133 (1), p.138-144

2001

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The Second Extracellular Loop of CCR5 Is the Major Determinant of Ligand Specificity

The Journal of biological chemistry, 1997-10, Vol.272 (40), p.24934-24941

1997

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Short‐term control of glucokinase activity: role of a regulatory protein

The FASEB journal, 1994-04, Vol.8 (6), p.414-419

1994

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Agonist and antagonist activities on human NPFF2 receptors of the NPY ligands GR231118 and BIBP3226

British journal of pharmacology, 2001-05, Vol.133 (1), p.1-4

2001

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Abstract 3261: EOS100850, a non-brain penetrant highly selective A2Areceptor antagonist, uniquely maintains high potency within the adenosine rich tumor microenvironment

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3261-3261

2019

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Abstract LB-114: a-TIGIT antagonist antibody EOS884448 shows dual mechanism of action by restoration of T cell effector functions and preferential depletion of Treg

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.LB-114-LB-114

2018

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Abstract 3278: EOS100850 potently restores adenosine A2Areceptor-dependent suppression of T cell function in the adenosine rich tumor microenvironment

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3278-3278

2019

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Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor

Journal of neurochemistry, 2004-07, Vol.90 (2), p.472-478

2004

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Abstract 4612: Development and validation of a screening platform for the identification of novel immuno-oncology targets

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4612-4612

2017

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Abstract 1683: A novel adenosine A2A receptor antagonist optimized for high potency in adenosine-rich tumor microenvironment boosts antitumor immunity

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1683-1683

2017

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Design and in vitro characterization of PAC1/VPAC1-selective agonists with potent neuroprotective effects

Biochemical pharmacology, 2011-02, Vol.81 (4), p.552-561

2011

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Abstract LB-291: EOS100850, an insurmountable and non-brain penetrant A2A receptor antagonist, inhibits adenosine-mediated T cell suppression, demonstrates anti-tumor activity and exhibits best-in class characteristics

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.LB-291-LB-291

2018

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iTeos Therapeutics

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia

Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation

Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids

The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54

Identification of a Novel Human ADP Receptor Coupled to Gi

Vasopressin-like peptide and its receptor function in an indirect diuretic signaling pathway in the red flour beetle

Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties

Identification and characterization of an endogenous chemotactic ligand specific for FPRL2

Identification of Natural Ligands for the Orphan G Protein-coupled Receptors GPR7 and GPR8

Pharmacological characterization of human NPFF1 and NPFF2 receptors expressed in CHO cells by using NPY Y1 receptor antagonists

The Orexin OX1 Receptor Activates a Novel Ca2+ Influx Pathway Necessary for Coupling to Phospholipase C

Functional characterization of a human receptor for neuropeptide FF and related peptides

The Second Extracellular Loop of CCR5 Is the Major Determinant of Ligand Specificity

Short‐term control of glucokinase activity: role of a regulatory protein

Oxysterols direct immune cell migration via EBI2

Agonist and antagonist activities on human NPFF2 receptors of the NPY ligands GR231118 and BIBP3226

Abstract 3261: EOS100850, a non-brain penetrant highly selective A2Areceptor antagonist, uniquely maintains high potency within the adenosine rich tumor microenvironment

Abstract LB-114: a-TIGIT antagonist antibody EOS884448 shows dual mechanism of action by restoration of T cell effector functions and preferential depletion of Treg

Abstract 3278: EOS100850 potently restores adenosine A2Areceptor-dependent suppression of T cell function in the adenosine rich tumor microenvironment

Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor

Abstract 4612: Development and validation of a screening platform for the identification of novel immuno-oncology targets

Abstract 1683: A novel adenosine A2A receptor antagonist optimized for high potency in adenosine-rich tumor microenvironment boosts antitumor immunity

Design and in vitro characterization of PAC1/VPAC1-selective agonists with potent neuroprotective effects

Abstract LB-291: EOS100850, an insurmountable and non-brain penetrant A2A receptor antagonist, inhibits adenosine-mediated T cell suppression, demonstrates anti-tumor activity and exhibits best-in class characteristics

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