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Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

Toxicological sciences, 2011-11, Vol.124 (1), p.1-22

2011

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Ligand Promiscuity of Aryl Hydrocarbon Receptor Agonists and Antagonists Revealed by Site-Directed Mutagenesis

Molecular and cellular biology, 2014-05, Vol.34 (9), p.1707-1719

2014

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Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease

Kidney international, 2018-04, Vol.93 (4), p.986-999

2018

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Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5997), p.1345-1348

2010

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Using Estrogenic Activity and Nontargeted Chemical Analysis to Identify Contaminants in Sewage Sludge

Environmental science & technology, 2021-05, Vol.55 (10), p.6729-6739

2021

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Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

Annual review of pharmacology and toxicology, 2003-01, Vol.43 (1), p.309-334

2003

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Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling

Environmental science & technology, 2015-12, Vol.49 (24), p.14614-14624

2015

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In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride

Environmental health perspectives, 2017-08, Vol.125 (8), p.087015-087015

2017

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Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds

Toxicological sciences, 2013-06, Vol.133 (2), p.197-208

2013

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Modeling the binding of diverse ligands within the Ah receptor ligand binding domain

Scientific reports, 2019-07, Vol.9 (1), p.10693-14, Article 10693

2019

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Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form

International journal of molecular sciences, 2020-04, Vol.21 (7), p.2474

2020

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CH223191 Is a Ligand-Selective Antagonist of the Ah (Dioxin) Receptor

Toxicological sciences, 2010-10, Vol.117 (2), p.393-403

2010

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Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2692

2018

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Development of a novel recombinant cell line for detection and characterization of Ah receptor nuclear translocation in intact cells

Toxicology in vitro, 2020-08, Vol.66, p.104873-104873, Article 104873

2020

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Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma

Nature communications, 2018-11, Vol.9 (1), p.4775-13, Article 4775

2018

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Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

PLoS computational biology, 2016-06, Vol.12 (6), p.e1004981

2016

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Malassezia Yeasts Produce a Collection of Exceptionally Potent Activators of the Ah (Dioxin) Receptor Detected in Diseased Human Skin

Journal of investigative dermatology, 2013-08, Vol.133 (8), p.2023-2030

2013

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Estrogenic Activity Measurements in Water Using Diffusive Gradients in Thin-Film Coupled with an Estrogen Bioassay

Analytical chemistry (Washington), 2017-12, Vol.89 (24), p.13357-13364

2017

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In situ measurement of estrogenic activity in various aquatic systems using organic diffusive gradients in thin-film coupled with ERE-CALUX bioassay

Environment international, 2019-06, Vol.127, p.13-20

2019

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Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor

PloS one, 2014-07, Vol.9 (7), p.e101832

2014

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Effects of Neonicotinoids on Promoter-Specific Expression and Activity of Aromatase (CYP19) in Human Adrenocortical Carcinoma (H295R) and Primary Umbilical Vein Endothelial (HUVEC) Cells

Review of Economic Dynamics, 2016-01, Vol.149 (1), p.134-144

2016

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Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits

Environmental science & technology, 2015-10, Vol.49 (19), p.11903-11912

2015

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And now for something completely different: Diversity in ligand-dependent activation of Ah receptor responses

Current opinion in toxicology, 2017-02, Vol.2, p.124-131

2017

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Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon–contaminated soils

Environmental toxicology and chemistry, 2018-02, Vol.37 (2), p.385-397

2018

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Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water

Water research (Oxford), 2017-10, Vol.123, p.734-750

2017

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Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

Ligand Promiscuity of Aryl Hydrocarbon Receptor Agonists and Antagonists Revealed by Site-Directed Mutagenesis

Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

Using Estrogenic Activity and Nontargeted Chemical Analysis to Identify Contaminants in Sewage Sludge

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling

In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride

Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds

Modeling the binding of diverse ligands within the Ah receptor ligand binding domain

Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form

CH223191 Is a Ligand-Selective Antagonist of the Ah (Dioxin) Receptor

Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist

Development of a novel recombinant cell line for detection and characterization of Ah receptor nuclear translocation in intact cells

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma

Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

Malassezia Yeasts Produce a Collection of Exceptionally Potent Activators of the Ah (Dioxin) Receptor Detected in Diseased Human Skin

Estrogenic Activity Measurements in Water Using Diffusive Gradients in Thin-Film Coupled with an Estrogen Bioassay

In situ measurement of estrogenic activity in various aquatic systems using organic diffusive gradients in thin-film coupled with ERE-CALUX bioassay

Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor

Effects of Neonicotinoids on Promoter-Specific Expression and Activity of Aromatase (CYP19) in Human Adrenocortical Carcinoma (H295R) and Primary Umbilical Vein Endothelial (HUVEC) Cells

Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits

And now for something completely different: Diversity in ligand-dependent activation of Ah receptor responses

Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon–contaminated soils

Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water

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