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Cell-Penetrating Peptides: Design, Development and Applications

1, 2022

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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

The Journal of cell biology, 2020-09, Vol.219 (9), p.1

2020

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Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids

ChemMedChem, 2021-04, Vol.16 (8), p.1226-1233

2021

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The Application of Microsampling Disks in Circular Dichroism Spectroscopy for Peptide and Nucleic Acid Drugs

Chemical and Pharmaceutical Bulletin, 2024/07/11, Vol.72(7), pp.658-663

2024

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N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride

Chemical and Pharmaceutical Bulletin, 2021/09/01, Vol.69(9), pp.872-876

2021

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Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates

Pharmaceutical research, 2022-01, Vol.39 (1), p.89-103

2022

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Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence

Molecules (Basel, Switzerland), 2021-01, Vol.26 (2), p.444

2021

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Recent Advances in PROTAC Technology Toward New Therapeutic Modalities

Chemistry & biodiversity, 2022-11, Vol.19 (11), p.e202200828-n/a

2022

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Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors

Bioorganic & medicinal chemistry, 2020-08, Vol.28 (15), p.115595-115595, Article 115595

2020

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Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4865-4869

2016

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Current Status and Challenges of Analytical Methods for Evaluation of Size and Surface Modification of Nanoparticle-Based Drug Formulations

AAPS PharmSciTech, 2022-05, Vol.23 (5), p.150-150, Article 150

2022

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Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Oncogene, 2020-05, Vol.39 (19), p.3867-3878

2020

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Development of Photoswitchable Estrogen Receptor Ligands

Chemical and Pharmaceutical Bulletin, 2020/04/01, Vol.68(4), pp.398-402

2020

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Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors

Journal of pharmacological sciences, 2022-12, Vol.150 (4), p.233-243

2022

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Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent

Chemical and Pharmaceutical Bulletin, 2020/08/01, Vol.68(8), pp.797-801

2020

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Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6847

2022

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Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

Chemical communications (Cambridge, England), 2019-07, Vol.55 (54), p.7792-7795

2019

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Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction

Chemical and Pharmaceutical Bulletin, 2024/05/15, Vol.72(5), pp.471-474

2024

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Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine

Journal of peptide science, 2021-12, Vol.27 (12), p.e3360-n/a

2021

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The effects of magainin 2-derived and rationally designed antimicrobial peptides on Mycoplasma pneumoniae

PloS one, 2022-01, Vol.17 (1), p.e0261893-e0261893

2022

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Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers

International journal of molecular sciences, 2023-07, Vol.24 (14), p.11768

2023

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Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

Pharmaceuticals (Basel, Switzerland), 2020-04, Vol.13 (4), p.74

2020

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Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Cancer science, 2013-11, Vol.104 (11), p.1492-1498

2013

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Copper‐Catalyzed Enantioselective Synthesis of Oxazolines from Aminotriols via Asymmetric Desymmetrization

Chemistry, an Asian journal, 2020-03, Vol.15 (6), p.840-844

2020

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Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15868-15882

2021

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Cell-Penetrating Peptides: Design, Development and Applications

Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids

The Application of Microsampling Disks in Circular Dichroism Spectroscopy for Peptide and Nucleic Acid Drugs

N-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride

Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates

Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence

Recent Advances in PROTAC Technology Toward New Therapeutic Modalities

Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Current Status and Challenges of Analytical Methods for Evaluation of Size and Surface Modification of Nanoparticle-Based Drug Formulations

Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Development of Photoswitchable Estrogen Receptor Ligands

Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors

Facile Synthesis of Kwakhurin, a Marker Compound of Pueraria mirifica and Its Quantitative NMR Analysis for Standardization as a Reagent

Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues

Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction

Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine

The effects of magainin 2-derived and rationally designed antimicrobial peptides on Mycoplasma pneumoniae

Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Copper‐Catalyzed Enantioselective Synthesis of Oxazolines from Aminotriols via Asymmetric Desymmetrization

Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design

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