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Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers

British journal of clinical pharmacology, 2000-01, Vol.49 (S1), p.43-47

2000

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CI-1007, a dopamine partial agonist and potential antipsychotic agent. I. Neurochemical effects

The Journal of pharmacology and experimental therapeutics, 1995-08, Vol.274 (2), p.898

1995

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Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907

The Journal of pharmacology and experimental therapeutics, 1995-12, Vol.275 (3), p.1355

1995

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5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety

Journal of medicinal chemistry, 1995-07, Vol.38 (15), p.2802

1995

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Agonist properties of a stable hexapeptide analog of neurotensin, NαMeArg-Lys-Pro-Trp-tLeu-Leu (NT1)

Biochemical pharmacology, 1995-04, Vol.49 (8), p.1147-1154

1995

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Evaluation of quaternized and neutral muscarinic receptor ligands in normal and DES-treated rat

International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1991, Vol.18 (5), p.557-561

1991

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5,7-Dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]ethyl]-6H-pyrrolo[3,2-f]-1,2-benzisoxazol-6-one : a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety

Journal of medicinal chemistry, 1995, Vol.38 (15), p.2802-2808

1995

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ChemInform Abstract: 5,7-Dihydro-3-(2-(1-(phenylmethyl)-4-piperidinyl)ethyl)-6H-pyrrolo(3,2- f)-1,2-benzisoxazol-6-one: A Potent and Centrally-Selective Inhibitor of Acetylcholinesterase with an Improved Margin of Safety

ChemInform, 1995-11, Vol.26 (48), p.no-no

1995

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TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

The Journal of experimental medicine, 2016-05, Vol.213 (5), p.667-675

2016

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Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease

The New England journal of medicine, 2018-01, Vol.378 (4), p.321-330

2018

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A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Neuron (Cambridge, Mass.), 2012-12, Vol.76 (5), p.908-920

2012

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Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Molecular neurodegeneration, 2023-08, Vol.18 (1), p.1-59, Article 59

2023

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Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (38), p.15502-15507

2012

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Brain to Plasma Amyloid-β Efflux: A Measure of Brain Amyloid Burden in a Mouse Model of Alzheimer's Disease

Science (American Association for the Advancement of Science), 2002-03, Vol.295 (5563), p.2264-2267

2002

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Peripheral Anti-Aβ Antibody Alters CNS and Plasma Aβ Clearance and Decreases Brain Aβ Burden in a Mouse Model of Alzheimer's Disease

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (15), p.8850-8855

2001

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Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

Nature neuroscience, 2002-05, Vol.5 (5), p.452-457

2002

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

Science translational medicine, 2011-06, Vol.3 (89), p.89ra57

2011

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Clusterin Promotes Amyloid Plaque Formation and is Critical for Neuritic Toxicity in a Mouse Model of Alzheimer's Disease

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10843-10848

2002

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ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition: Evidence that ApoE Regulates Extracellular Aβ Metabolism In Vivo

Neuron (Cambridge, Mass.), 2004-01, Vol.41 (2), p.193-202

2004

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In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life

The Journal of neuroscience, 2003-10, Vol.23 (26), p.8844-8853

2003

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Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Molecular neurodegeneration, 2018-12, Vol.13 (1), p.65-65, Article 65

2018

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Midlife Blood Pressure, Plasma β-Amyloid, and the Risk for Alzheimer Disease: The Honolulu Asia Aging Study

Hypertension (Dallas, Tex. 1979), 2012-04, Vol.59 (4), p.780-786

2012

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Safety and biomarker effects of solanezumab in patients with Alzheimer’s disease

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.261-271

2012

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A γ-secretase inhibitor decreases amyloid-β production in the central nervous system

Annals of neurology, 2009-07, Vol.66 (1), p.48-54

2009

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Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers

CI-1007, a dopamine partial agonist and potential antipsychotic agent. I. Neurochemical effects

Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907

5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety

Agonist properties of a stable hexapeptide analog of neurotensin, NαMeArg-Lys-Pro-Trp-tLeu-Leu (NT1)

Evaluation of quaternized and neutral muscarinic receptor ligands in normal and DES-treated rat

5,7-Dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]ethyl]-6H-pyrrolo[3,2-f]-1,2-benzisoxazol-6-one : a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety

ChemInform Abstract: 5,7-Dihydro-3-(2-(1-(phenylmethyl)-4-piperidinyl)ethyl)-6H-pyrrolo(3,2- f)-1,2-benzisoxazol-6-one: A Potent and Centrally-Selective Inhibitor of Acetylcholinesterase with an Improved Margin of Safety

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis

Brain to Plasma Amyloid-β Efflux: A Measure of Brain Amyloid Burden in a Mouse Model of Alzheimer's Disease

Peripheral Anti-Aβ Antibody Alters CNS and Plasma Aβ Clearance and Decreases Brain Aβ Burden in a Mouse Model of Alzheimer's Disease

Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis

Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

Clusterin Promotes Amyloid Plaque Formation and is Critical for Neuritic Toxicity in a Mouse Model of Alzheimer's Disease

ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition: Evidence that ApoE Regulates Extracellular Aβ Metabolism In Vivo

In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life

Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Midlife Blood Pressure, Plasma β-Amyloid, and the Risk for Alzheimer Disease: The Honolulu Asia Aging Study

Safety and biomarker effects of solanezumab in patients with Alzheimer’s disease

A γ-secretase inhibitor decreases amyloid-β production in the central nervous system

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