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Impaired meningeal lymphatic vessel development worsens stroke outcome

Journal of cerebral blood flow and metabolism, 2020-02, Vol.40 (2), p.263-275

2020

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Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis

Cancer research (Chicago, Ill.), 2015-09, Vol.75 (18), p.3699-3705

2015

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Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature

PloS one, 2013-09, Vol.8 (9), p.e74686-e74686

2013

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The emergence of targetable MEKanisms in sporadic lymphatic disorders

EMBO molecular medicine, 2020-10, Vol.12 (10), p.e12822-n/a

2020

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Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

Developmental biology, 2011-06, Vol.354 (2), p.253-266

2011

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Collagen Signaling Enhances Tumor Progression after Anti-VEGF Therapy in a Murine Model of Pancreatic Ductal Adenocarcinoma

Cancer research (Chicago, Ill.), 2014-02, Vol.74 (4), p.1032-1044

2014

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Trametinib inhibits lymphatic vessel invasion of bone in a mouse model of Gorham-Stout disease

Journal of vascular anomalies (Philadelphia, Pa.), 2023-12, Vol.4 (4), p.e070

2023

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Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.15999-16004

2014

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Identification of Gene Expression Differences between Lymphangiogenic and Non-Lymphangiogenic Non-Small Cell Lung Cancer Cell Lines

PloS one, 2016-03, Vol.11 (3), p.e0150963-e0150963

2016

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VEGF-C promotes the development of lymphatics in bone and bone loss

eLife, 2018-04, Vol.7

2018

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KRAS-driven model of Gorham-Stout disease effectively treated with trametinib

JCI insight, 2021-08, Vol.6 (15)

2021

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Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts

Molecular cancer therapeutics, 2009-07, Vol.8 (7), p.1761-1771

2009

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Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Frontiers in cell and developmental biology, 2023-09, Vol.11, p.1276333-1276333

2023

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Lymphatics in bone arise from pre-existing lymphatics

Development (Cambridge), 2020-04, Vol.147 (21)

2020

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Mir-126 is a conserved modulator of lymphatic development

Developmental biology, 2018-05, Vol.437 (2), p.120-130

2018

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Heterozygous Mutation of Vegfr3 Reduces Renal Lymphatics without Renal Dysfunction

Journal of the American Society of Nephrology, 2021-12, Vol.32 (12), p.3099-3113

2021

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Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly

The Journal of experimental medicine, 2019-02, Vol.216 (2), p.407-418

2019

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Lymphatics in bone arise from preexisting lymphatics

Development (Cambridge), 2020-01

2020

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Chy‐3 mice are Vegfc haploinsufficient and exhibit defective dermal superficial to deep lymphatic transition and dermal lymphatic hypoplasia

Developmental dynamics, 2007-08, Vol.236 (8), p.2346-2355

2007

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Lymphangiogenesis, lymphatic systemomics, and cancer: context, advances and unanswered questions

Clinical & experimental metastasis, 2018-08, Vol.35 (5-6), p.419-424

2018

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Hyperplasia, de novo lymphangiogenesis, and lymphatic regression in mice with tissue-specific, inducible overexpression of murine VEGF-D

American journal of physiology. Heart and circulatory physiology, 2016-08, Vol.311 (2), p.H384-H394

2016

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Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer

Molecular cancer research, 2019-02, Vol.17 (2), p.348-355

2019

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RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas

Cancer discovery, 2013-04, Vol.3 (4), p.444-457

2013

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Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts

Molecular cancer therapeutics, 2012-11, Vol.11 (11), p.2473-2482

2012

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Overlapping biomarkers, pathways, processes and syndromes in lymphatic development, growth and neoplasia

Clinical & experimental metastasis, 2012-10, Vol.29 (7), p.707-727

2012

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Impaired meningeal lymphatic vessel development worsens stroke outcome

Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis

Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature

The emergence of targetable MEKanisms in sporadic lymphatic disorders

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

Collagen Signaling Enhances Tumor Progression after Anti-VEGF Therapy in a Murine Model of Pancreatic Ductal Adenocarcinoma

Trametinib inhibits lymphatic vessel invasion of bone in a mouse model of Gorham-Stout disease

Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK

Identification of Gene Expression Differences between Lymphangiogenic and Non-Lymphangiogenic Non-Small Cell Lung Cancer Cell Lines

VEGF-C promotes the development of lymphatics in bone and bone loss

KRAS-driven model of Gorham-Stout disease effectively treated with trametinib

Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Lymphatics in bone arise from pre-existing lymphatics

Mir-126 is a conserved modulator of lymphatic development

Heterozygous Mutation of Vegfr3 Reduces Renal Lymphatics without Renal Dysfunction

Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly

Lymphatics in bone arise from preexisting lymphatics

Chy‐3 mice are Vegfc haploinsufficient and exhibit defective dermal superficial to deep lymphatic transition and dermal lymphatic hypoplasia

Lymphangiogenesis, lymphatic systemomics, and cancer: context, advances and unanswered questions

Hyperplasia, de novo lymphangiogenesis, and lymphatic regression in mice with tissue-specific, inducible overexpression of murine VEGF-D

Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer

RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas

Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts

Overlapping biomarkers, pathways, processes and syndromes in lymphatic development, growth and neoplasia

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