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CHK2 kinase in the DNA damage response and beyond

Journal of molecular cell biology, 2014-12, Vol.6 (6), p.442-457

2014

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The DNA damage response pathway in normal hematopoiesis and malignancies

International journal of hematology, 2017-09, Vol.106 (3), p.328-334

2017

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Hypoxia in the regulation of neural stem cells

Cellular and molecular life sciences : CMLS, 2011-09, Vol.68 (17), p.2831-2844

2011

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TSPYL2 is a novel regulator of SIRT1 and p300 activity in response to DNA damage

Cell death and differentiation, 2019-05, Vol.26 (5), p.918-931

2019

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Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing

Scientific reports, 2021-01, Vol.11 (1), p.651-651, Article 651

2021

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Highly tumorigenic lung cancer CD133⁺ cells display stem-like features and are spared by cisplatin treatment

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16281-16286

2009

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Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab

Clinical cancer research, 2009-03, Vol.15 (6), p.2010-2021

2009

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Mild hypoxia enhances proliferation and multipotency of human neural stem cells

PloS one, 2010-01, Vol.5 (1), p.e8575-e8575

2010

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Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF–positive leukemic cells

Cancer letters, 2017-02, Vol.386, p.131-140

2017

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Separase prevents genomic instability by controlling replication fork speed

Nucleic acids research, 2018-01, Vol.46 (1), p.267-278

2018

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DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage

Journal of molecular cell biology, 2012-10, Vol.4 (5), p.294-303

2012

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TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC

Molecular cancer research, 2014-05, Vol.12 (5), p.660-669

2014

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DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients

Scientific reports, 2019-01, Vol.9 (1), p.651-651, Article 651

2019

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MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner

Journal of hematology and oncology, 2018-03, Vol.11 (1), p.45-45, Article 45

2018

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Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt

Oncogene, 2004-07, Vol.23 (34), p.5781-5791

2004

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EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells

PloS one, 2014-09, Vol.9 (9), p.e107165

2014

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Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2

Molecular cancer therapeutics, 2007-03, Vol.6 (3), p.935-944

2007

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Long-term survival of human neural stem cells in the ischemic rat brain upon transient immunosuppression

PloS one, 2010-11, Vol.5 (11), p.e14035-e14035

2010

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Pressure Overload Activates DNA-Damage Response in Cardiac Stromal Cells: A Novel Mechanism Behind Heart Failure With Preserved Ejection Fraction?

Frontiers in cardiovascular medicine, 2022-06, Vol.9, p.878268-878268

2022

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REGγ/PA28γ proteasome activator interacts with PML and Chk2 and affects PML nuclear bodies number

Cell cycle (Georgetown, Tex.), 2009-08, Vol.8 (15), p.2399-2407

2009

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Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

Cancer cell, 2006-12, Vol.10 (6), p.473-486

2006

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Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic

PloS one, 2012-11, Vol.7 (11), p.e49527-e49527

2012

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DNA Damage-Induced Cell Cycle Regulation and Function of Novel Chk2 Phosphoresidues

Molecular and Cellular Biology, 2006-11, Vol.26 (21), p.7832-7845

2006

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Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks

Oncogene, 2004-10, Vol.23 (46), p.7691-7700

2004

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NFBD1/MDC1 Associates with p53 and Regulates Its Function at the Crossroad between Cell Survival and Death in Response to DNA Damage

The Journal of biological chemistry, 2007-08, Vol.282 (31), p.22993-23004

2007

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CHK2 kinase in the DNA damage response and beyond

The DNA damage response pathway in normal hematopoiesis and malignancies

Hypoxia in the regulation of neural stem cells

TSPYL2 is a novel regulator of SIRT1 and p300 activity in response to DNA damage

Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing

Highly tumorigenic lung cancer CD133⁺ cells display stem-like features and are spared by cisplatin treatment

Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab

Mild hypoxia enhances proliferation and multipotency of human neural stem cells

Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF–positive leukemic cells

Separase prevents genomic instability by controlling replication fork speed

DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage

TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC

DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients

MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner

Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt

EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells

Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2

Long-term survival of human neural stem cells in the ischemic rat brain upon transient immunosuppression

Pressure Overload Activates DNA-Damage Response in Cardiac Stromal Cells: A Novel Mechanism Behind Heart Failure With Preserved Ejection Fraction?

REGγ/PA28γ proteasome activator interacts with PML and Chk2 and affects PML nuclear bodies number

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic

DNA Damage-Induced Cell Cycle Regulation and Function of Novel Chk2 Phosphoresidues

Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks

NFBD1/MDC1 Associates with p53 and Regulates Its Function at the Crossroad between Cell Survival and Death in Response to DNA Damage

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