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A Single Amino Acid Substitution in the Envelope Protein of Chimeric Yellow Fever-Dengue 1 Vaccine Virus Reduces Neurovirulence for Suckling Mice and Viremia/Viscerotropism for Monkeys

Journal of Virology, 2004-09, Vol.78 (18), p.9998-10008

2004

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Immunogenicity, Genetic Stability, and Protective Efficacy of a Recombinant, Chimeric Yellow Fever-Japanese Encephalitis Virus (ChimeriVax-JE) as a Live, Attenuated Vaccine Candidate against Japanese Encephalitis

Virology (New York, N.Y.), 1999-05, Vol.257 (2), p.363-372

1999

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Recombinant, chimaeric live, attenuated vaccine (ChimeriVax™) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates

Vaccine, 1999-04, Vol.17 (15), p.1869-1882

1999

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Novel approaches for discovering industrial enzymes

Current opinion in microbiology, 1999-06, Vol.2 (3), p.241-245

1999

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Red-Shifted Excitation Mutants of the Green Fluorescent Protein

Bio/technology (New York, N.Y. 1983), 1995-02, Vol.13 (2), p.151-154

1995

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Recombinant, chimaeric live, attenuated vaccine (ChimeriVax super(TM)) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in nonhuman primates

Vaccine, 1999-04, Vol.17 (15-16), p.1869-1882

1999

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Directed evolution of PDZ variants to generate high-affinity detection reagents

Protein engineering, design and selection, 2005-04, Vol.18 (4), p.165-173

2005

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Application of a very high-throughput digital imaging screen to evolve the enzyme galactose oxidase

Protein engineering, 2001-04, Vol.14 (4), p.261-267

2001

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Novel approaches for discovering industrial enzymes : Ecology and industrial microbiology

Current opinion in microbiology, 1999, Vol.2 (3), p.241-245

1999

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In vitro evolution of proteins for drug development

Assay and drug development technologies, 2003-02, Vol.1 (1 Pt 2), p.187-198

2003

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Effects of humanization by variable domain resurfacing on the antiviral activity of a single-chain antibody against respiratory syncytial virus

Protein engineering, 1999-04, Vol.12 (4), p.357-362

1999

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Searching Sequence Space to Engineer Proteins: Exponential Ensemble Mutagenesis

Bio/technology (New York, N.Y. 1983), 1993-12, Vol.11 (12), p.1548-1552

1993

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[29] Digital imaging spectroscopy for massively parallel screening of mutants

Methods in Enzymology, 1995, Vol.246, p.732,IN1-748,IN4

1995

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Recursive ensemble mutagenesis

Protein engineering, 1993-04, Vol.6 (3), p.327-331

1993

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Context dependence of phenotype prediction and diversity in combinatorial mutagenesis

Protein engineering, 1995-03, Vol.8 (3), p.237-242

1995

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A method to prioritize the surveillance of chemicals in food commodities to access international market and its application to four countries in Sub-Saharan Africa

Environment international, 2020-02, Vol.135, p.105386, Article 105386

2020

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Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein

PloS one, 2024-04, Vol.19 (4), p.e0301773-e0301773

2024

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CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner

PloS one, 2015-06, Vol.10 (6), p.e0130517-e0130517

2015

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Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains

PloS one, 2017-11, Vol.12 (11), p.e0185666-e0185666

2017

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Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine

PloS one, 2018-06, Vol.13 (6), p.e0199452-e0199452

2018

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Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth

Journal of virology, 2020-02, Vol.94 (6)

2020

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Evaluation of the respiratory syncytial virus G-directed neutralizing antibody response in the human airway epithelial cell model

Virology (New York, N.Y.), 2020-11, Vol.550, p.21-26

2020

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Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate [DELTA]NS2/[DELTA]1313/I1314L increase the stability of infectivity and content of prefusion F protein

PloS one, 2024-04, Vol.19 (4), p.e0301773

2024

Volltextzugriff (PDF)

Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

Journal of virology, 2017-12, Vol.91 (24)

2017

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High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo

PloS one, 2013-02, Vol.8 (2), p.e57224-e57224

2013

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A Single Amino Acid Substitution in the Envelope Protein of Chimeric Yellow Fever-Dengue 1 Vaccine Virus Reduces Neurovirulence for Suckling Mice and Viremia/Viscerotropism for Monkeys

Immunogenicity, Genetic Stability, and Protective Efficacy of a Recombinant, Chimeric Yellow Fever-Japanese Encephalitis Virus (ChimeriVax-JE) as a Live, Attenuated Vaccine Candidate against Japanese Encephalitis

Recombinant, chimaeric live, attenuated vaccine (ChimeriVax™) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates

Novel approaches for discovering industrial enzymes

Red-Shifted Excitation Mutants of the Green Fluorescent Protein

Recombinant, chimaeric live, attenuated vaccine (ChimeriVax super(TM)) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in nonhuman primates

Directed evolution of PDZ variants to generate high-affinity detection reagents

Application of a very high-throughput digital imaging screen to evolve the enzyme galactose oxidase

Novel approaches for discovering industrial enzymes : Ecology and industrial microbiology

In vitro evolution of proteins for drug development

Effects of humanization by variable domain resurfacing on the antiviral activity of a single-chain antibody against respiratory syncytial virus

Searching Sequence Space to Engineer Proteins: Exponential Ensemble Mutagenesis

[29] Digital imaging spectroscopy for massively parallel screening of mutants

Recursive ensemble mutagenesis

Context dependence of phenotype prediction and diversity in combinatorial mutagenesis

A method to prioritize the surveillance of chemicals in food commodities to access international market and its application to four countries in Sub-Saharan Africa

Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein

CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner

Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains

Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine

Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth

Evaluation of the respiratory syncytial virus G-directed neutralizing antibody response in the human airway epithelial cell model

Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate [DELTA]NS2/[DELTA]1313/I1314L increase the stability of infectivity and content of prefusion F protein

Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo

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