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Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials

Cancer research (Chicago, Ill.), 2013-08, Vol.73 (16), p.4965-4977

2013

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Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic Testing

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15), p.2969-2974

2015

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More than the genes, the tumor microenvironment in neuroblastoma

Cancer letters, 2016-09, Vol.380 (1), p.304-314

2016

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Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity

PloS one, 2015-07, Vol.10 (7), p.e0133786-e0133786

2015

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Protumorigenic Activity of Plasminogen Activator Inhibitor-1 Through an Antiapoptotic Function

JNCI : Journal of the National Cancer Institute, 2012-10, Vol.104 (19), p.1470-1484

2012

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Bone marrow-derived mesenchymal stromal cells promote survival and drug resistance in tumor cells

Molecular cancer therapeutics, 2014-04, Vol.13 (4), p.962-975

2014

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Critical Role of STAT3 in IL-6―Mediated Drug Resistance in Human Neuroblastoma

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (13), p.3852-3864

2013

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Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages

The Journal of clinical investigation, 2009-06, Vol.119 (6), p.1524-1536

2009

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A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma

Cancer research (Chicago, Ill.), 2012-05, Vol.72 (9), p.2228-2238

2012

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Fibroblasts and macrophages cooperate to create a pro-tumorigenic and immune resistant environment via activation of TGF-β/IL-6 pathway in neuroblastoma

Oncoimmunology, 2022-12, Vol.11 (1), p.2146860-2146860

2022

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Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells

Cancer research (Chicago, Ill.), 2009-01, Vol.69 (1), p.329-337

2009

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The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche

Journal of extracellular vesicles, 2023-05, Vol.12 (5), p.e12326-n/a

2023

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Interleukin-6 in bone metastasis and cancer progression

European journal of cancer (1990), 2010-05, Vol.46 (7), p.1223-1231

2010

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Plasminogen Activator Inhibitor-1 Protects Endothelial Cells from FasL-Mediated Apoptosis

Cancer cell, 2008-10, Vol.14 (4), p.324-334

2008

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Modifying the soil to affect the seed: role of stromal-derived matrix metalloproteinases in cancer progression

Cancer and metastasis reviews, 2006-03, Vol.25 (1), p.35-43

2006

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Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC

Oncotarget, 2017-10, Vol.8 (53), p.91516-91529

2017

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Cancer-Associated Fibroblasts: Understanding Their Heterogeneity

Cancers, 2020-10, Vol.12 (11), p.3108

2020

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Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells

Journal of extracellular vesicles, 2017-12, Vol.6 (1), p.1332941-n/a

2017

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Synergistic Activity of Fenretinide and the Bcl-2 Family Protein Inhibitor ABT-737 against Human Neuroblastoma

Clinical cancer research, 2011-11, Vol.17 (22), p.7093-7104

2011

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Bone marrow-derived mesenchymal stem cells and the tumor microenvironment

Cancer and metastasis reviews, 2010-06, Vol.29 (2), p.249-261

2010

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Desmoplasia: a response or a niche?

Cancer discovery, 2012-09, Vol.2 (9), p.772-774

DeClerck, Yves A

2012

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Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment

Cancer research (Chicago, Ill.), 2004-03, Vol.64 (5), p.1675-1686

2004

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Identification of Galectin-3-binding Protein as a Factor Secreted by Tumor Cells That Stimulates Interleukin-6 Expression in the Bone Marrow Stroma

The Journal of biological chemistry, 2008-07, Vol.283 (27), p.18573-18581

2008

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Tumor microenvironment complexity: emerging roles in cancer therapy

Cancer research, 2012-05, Vol.72 (10), p.2473-2480

2012

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The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent

Cancer research (Chicago, Ill.), 2005-04, Vol.65 (8), p.3200-3208

2005

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Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials

Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic Testing

More than the genes, the tumor microenvironment in neuroblastoma

Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity

Protumorigenic Activity of Plasminogen Activator Inhibitor-1 Through an Antiapoptotic Function

Bone marrow-derived mesenchymal stromal cells promote survival and drug resistance in tumor cells

Critical Role of STAT3 in IL-6―Mediated Drug Resistance in Human Neuroblastoma

Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages

A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma

Fibroblasts and macrophages cooperate to create a pro-tumorigenic and immune resistant environment via activation of TGF-β/IL-6 pathway in neuroblastoma

Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells

The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche

Interleukin-6 in bone metastasis and cancer progression

Plasminogen Activator Inhibitor-1 Protects Endothelial Cells from FasL-Mediated Apoptosis

Modifying the soil to affect the seed: role of stromal-derived matrix metalloproteinases in cancer progression

Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC

Cancer-Associated Fibroblasts: Understanding Their Heterogeneity

Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells

Synergistic Activity of Fenretinide and the Bcl-2 Family Protein Inhibitor ABT-737 against Human Neuroblastoma

Bone marrow-derived mesenchymal stem cells and the tumor microenvironment

Desmoplasia: a response or a niche?

Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment

Identification of Galectin-3-binding Protein as a Factor Secreted by Tumor Cells That Stimulates Interleukin-6 Expression in the Bone Marrow Stroma

Tumor microenvironment complexity: emerging roles in cancer therapy

The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent

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