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Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation

The Journal of clinical investigation, 2014-02, Vol.124 (2), p.580-591

2014

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Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms

Oncogene, 2020-07, Vol.39 (31), p.5323-5337

2020

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Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Blood, 2013-10, Vol.122 (18), p.3178-3187

2013

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Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling

Blood, 2008-10, Vol.112 (8), p.3164-3174

2008

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RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization

Nature communications, 2012-03, Vol.3 (1), p.717-717, Article 717

2012

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Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

Blood, 2016-12, Vol.128 (26), p.3137-3145

2016

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Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

Nature communications, 2017-11, Vol.8 (1), p.1786-17, Article 1786

2017

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A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

Blood, 2014-10, Vol.124 (16), p.2554-2563

2014

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A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis

Blood, 2009-08, Vol.114 (8), p.1506-1517

2009

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AIF deficiency compromises oxidative phosphorylation

The EMBO journal, 2004-11, Vol.23 (23), p.4679-4689

2004

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MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Blood, 2009-11, Vol.114 (19), p.4221-4232

2009

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TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Stem cells (Dayton, Ohio), 2014-08, Vol.32 (8), p.2084-2097

2014

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Crucial role for endoplasmic reticulum stress during megakaryocyte maturation

Arteriosclerosis, thrombosis, and vascular biology, 2013-12, Vol.33 (12), p.2750

2013

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Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia

Blood, 2011-12, Vol.118 (24), p.6310-6320

2011

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An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

The Journal of experimental medicine, 2009-08, Vol.206 (8), p.1701-1707

2009

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Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint

Haematologica (Roma), 2016-12, Vol.101 (12), p.1469

2016

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Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

Blood, 2007-04, Vol.109 (8), p.3225-3234

2007

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Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients

PloS one, 2013, Vol.8 (9), p.e74257-e74257

2013

Volltextzugriff (PDF)

Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera

Experimental hematology, 2004-02, Vol.32 (2), p.179-187

2004

Volltextzugriff (PDF)

Megakaryocyte and polyploidization

Experimental hematology, 2018-01, Vol.57, p.1-13

2018

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P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Blood, 2008-04, Vol.111 (8), p.4081-4091

2008

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Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

Blood, 2000-09, Vol.96 (5), p.1798-1807

2000

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Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation

Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome

Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling

RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis

AIF deficiency compromises oxidative phosphorylation

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Crucial role for endoplasmic reticulum stress during megakaryocyte maturation

Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia

An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients

Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera

Megakaryocyte and polyploidization

P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

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