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Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation

The Journal of clinical investigation, 2014-02, Vol.124 (2), p.580-591

2014

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Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Blood, 2013-10, Vol.122 (18), p.3178-3187

2013

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Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling

Blood, 2008-10, Vol.112 (8), p.3164-3174

2008

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Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

Blood, 2016-12, Vol.128 (26), p.3137-3145

2016

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Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

Nature communications, 2017-11, Vol.8 (1), p.1786-17, Article 1786

2017

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A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

Blood, 2014-10, Vol.124 (16), p.2554-2563

2014

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AIF deficiency compromises oxidative phosphorylation

The EMBO journal, 2004-11, Vol.23 (23), p.4679-4689

2004

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A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis

Blood, 2009-08, Vol.114 (8), p.1506-1517

2009

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Proplatelet formation is regulated by the Rho/ROCK pathway

Blood, 2007-05, Vol.109 (10), p.4229-4236

2007

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MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Blood, 2009-11, Vol.114 (19), p.4221-4232

2009

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TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Stem cells (Dayton, Ohio), 2014-08, Vol.32 (8), p.2084-2097

2014

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Crucial role for endoplasmic reticulum stress during megakaryocyte maturation

Arteriosclerosis, thrombosis, and vascular biology, 2013-12, Vol.33 (12), p.2750

2013

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An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

The Journal of experimental medicine, 2009-08, Vol.206 (8), p.1701-1707

2009

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Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

Blood, 2007-04, Vol.109 (8), p.3225-3234

2007

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Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients

PloS one, 2013, Vol.8 (9), p.e74257-e74257

2013

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Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera

Experimental hematology, 2004-02, Vol.32 (2), p.179-187

2004

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Megakaryocyte and polyploidization

Experimental hematology, 2018-01, Vol.57, p.1-13

2018

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P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Blood, 2008-04, Vol.111 (8), p.4081-4091

2008

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Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

Blood, 2000-09, Vol.96 (5), p.1798-1807

2000

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c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

Nature (London), 1994-06, Vol.369 (6481), p.571-574

1994

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Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome

Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

AIF deficiency compromises oxidative phosphorylation

A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis

Proplatelet formation is regulated by the Rho/ROCK pathway

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia

Crucial role for endoplasmic reticulum stress during megakaryocyte maturation

An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients

Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera

Megakaryocyte and polyploidization

P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

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