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Potent Inhibition of Scrapie Prion Replication in Cultured Cells by Bis-Acridines

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (6), p.3416-3421

2003

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Synthesis and Cytotoxic Activity of 7-Oxo-7H-dibenz[f , i j]isoquinoline and 7-Oxo-7H-benzo[e]perimidine Derivatives

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.2004-2014

2001

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Synthesis and cytotoxic activity of carboxamide derivatives of benzo[ b][1,6]naphthyridin-(5 H)ones

Bioorganic & medicinal chemistry, 2005-02, Vol.13 (4), p.1341-1355

2005

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Synthesis and Cytotoxic Activity of Carboxamide Derivatives of Benzo[b][1,6]naphthyridines

Journal of medicinal chemistry, 2003-03, Vol.46 (6), p.1049-1054

2003

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Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides

Bioorganic & medicinal chemistry, 2000-05, Vol.8 (5), p.977-984

2000

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Synthesis, antimalarial activity and inhibition of haem detoxification of novel bisquinolines

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2075-2077

2001

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Synthesis and biological evaluation of substituted 3-anilino-quinolin-2(1H)-ones as PDK1 inhibitors

Bioorganic & medicinal chemistry, 2014-07, Vol.22 (14), p.3781-3790

2014

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Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors

Bioorganic & medicinal chemistry, 2014-08, Vol.22 (15), p.3879-3886

2014

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Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation

Organic & biomolecular chemistry, 2016-01, Vol.14 (20), p.4617-4639

2016

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Synthesis and biological evaluation of substituted 2-anilino-7H-pyrrolopyrimidines as PDK1 inhibitors

Tetrahedron, 2014-08, Vol.70 (33), p.4947-4956

2014

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Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum

Biochemical pharmacology, 2005-10, Vol.70 (8), p.1158-1166

2005

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Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of β-haematin

Biochemical pharmacology, 2002-03, Vol.63 (5), p.833-842

2002

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Potent Inhibitors of Phosphatidylinositol3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms

ChemMedChem, 2013-06, Vol.8 (6), p.914

2013

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Synthesis and Activity of Some Antimalarial Bisquinolines

Journal of medicinal chemistry, 1995-01, Vol.38 (1), p.204-206

1995

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Potent Inhibitors of Phosphatidylinositol 3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms

ChemMedChem, 2013-06, Vol.8 (6), p.914-918

2013

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Synthesis and Antitumor Properties of N-[2-(Dimethylamino)ethyl]carboxamide Derivatives of Fused Tetracyclic Quinolines and Quinoxalines: A New Class of Putative Topoisomerase Inhibitors

Journal of medicinal chemistry, 1997-06, Vol.40 (13), p.2040-2046

1997

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Positioning of the carboxamide side chain in 11-oxo-11H-indeno[1,2-b]quinolinecarboxamide anticancer agents : Effects on cytotoxicity

Bioorganic & medicinal chemistry, 2001-02, Vol.9 (2), p.445-452

2001

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Reduced Benzimidazo[2,1-a]isoquinolines. Synthesis and Cytotoxicity Studies

Australian journal of chemistry, 2001, Vol.54 (8), p.529

2001

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Electron-Deficient DNA Intercalating Agents as Antitumor Drugs: Aza Analogs of the Experimental Clinical Agent N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide

Journal of medicinal chemistry, 1994-03, Vol.37 (5), p.593-597

1994

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Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]carboxamide derivatives of 7-oxo-7H-benz[de]anthracene, 7-oxo-7H-naphtho[1,2,3-de]quinoline, and 7-oxo-7H-benzo[e]perimidine

Bioorganic & medicinal chemistry, 2005-06, Vol.13 (11), p.3657-3665

2005

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Synthesis and reactivity of some imidazo-, triazolo- and tetrazolo-isoquinoline derivatives

Journal of heterocyclic chemistry, 2004-07, Vol.41 (4), p.549-555

2004

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Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites

Biochemical pharmacology, 2004-04, Vol.67 (7), p.1347-1353

2004

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The Multidrug Resistance Protein Is Photoaffinity Labeled by a Quinoline-Based Drug at Multiple Sites

Biochemistry (Easton), 2000-05, Vol.39 (20), p.6094-6102

2000

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Synthesis and cytotoxicity of potential anticancer derivatives of pyrazolo[3,4,5- kl]acridine and indolo[2,3- a]acridine

Tetrahedron, 2002, Vol.58 (1), p.175-181

2002

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Synthesis of substituted indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides : Evaluation of structure-activity relationships for cytotoxicity

Bioorganic & medicinal chemistry, 2000-10, Vol.8 (10), p.2461-2466

2000

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Potent Inhibition of Scrapie Prion Replication in Cultured Cells by Bis-Acridines

Synthesis and Cytotoxic Activity of 7-Oxo-7H-dibenz[f , i j]isoquinoline and 7-Oxo-7H-benzo[e]perimidine Derivatives

Synthesis and cytotoxic activity of carboxamide derivatives of benzo[ b][1,6]naphthyridin-(5 H)ones

Synthesis and Cytotoxic Activity of Carboxamide Derivatives of Benzo[b][1,6]naphthyridines

Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides

Synthesis, antimalarial activity and inhibition of haem detoxification of novel bisquinolines

Synthesis and biological evaluation of substituted 3-anilino-quinolin-2(1H)-ones as PDK1 inhibitors

Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors

Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation

Synthesis and biological evaluation of substituted 2-anilino-7H-pyrrolopyrimidines as PDK1 inhibitors

Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum

Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of β-haematin

Potent Inhibitors of Phosphatidylinositol3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms

Synthesis and Activity of Some Antimalarial Bisquinolines

Potent Inhibitors of Phosphatidylinositol 3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms

Synthesis and Antitumor Properties of N-[2-(Dimethylamino)ethyl]carboxamide Derivatives of Fused Tetracyclic Quinolines and Quinoxalines: A New Class of Putative Topoisomerase Inhibitors

Positioning of the carboxamide side chain in 11-oxo-11H-indeno[1,2-b]quinolinecarboxamide anticancer agents : Effects on cytotoxicity

Reduced Benzimidazo[2,1-a]isoquinolines. Synthesis and Cytotoxicity Studies

Electron-Deficient DNA Intercalating Agents as Antitumor Drugs: Aza Analogs of the Experimental Clinical Agent N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide

Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]carboxamide derivatives of 7-oxo-7H-benz[de]anthracene, 7-oxo-7H-naphtho[1,2,3-de]quinoline, and 7-oxo-7H-benzo[e]perimidine

Synthesis and reactivity of some imidazo-, triazolo- and tetrazolo-isoquinoline derivatives

Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites

The Multidrug Resistance Protein Is Photoaffinity Labeled by a Quinoline-Based Drug at Multiple Sites

Synthesis and cytotoxicity of potential anticancer derivatives of pyrazolo[3,4,5- kl]acridine and indolo[2,3- a]acridine

Synthesis of substituted indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides : Evaluation of structure-activity relationships for cytotoxicity

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