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Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

The Journal of biological chemistry, 1999-03, Vol.274 (13), p.8694-8697

1999

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The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2709-2713

2001

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N-(3-Phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (5), p.885-890

2003

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Identification of Unique VLA-4 Antagonists from a Combinatorial Library

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (4), p.685-688

2002

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N-(Arylacetyl)-biphenylalanines as Potent VLA-4 Antagonists

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (16), p.2141-2144

2002

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N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (11), p.1497-1500

2002

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Potent, orally absorbed glucagon receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (5), p.641-646

1999

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A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor

Journal of medicinal chemistry, 1993-10, Vol.36 (21), p.3207-3210

1993

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N-Aryl-prolyl-dipeptides as potent antagonists of VLA-4

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (16), p.2205-2208

2002

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Substituted Imidazoles as Glucagon Receptor Antagonists

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2549-2553

2001

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Pyrroles and other heterocycles as inhibitors of P38 kinase

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (19), p.2689-2694

1998

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Total synthesis of (.+-.)-dysidin, a marine metabolite containing an N-acyl-O-methyltetramic acid

Journal of organic chemistry, 1984-09, Vol.49 (19), p.3489-3493

1984

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Total synthesis of halogenated monoterpene marine natural products via the Diels-Alder reaction

Journal of organic chemistry, 1985-10, Vol.50 (20), p.3738-3749

1985

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Deprotection of N- tert-butoxycarbonyl (Boc) groups in the presence of tert-butyl esters

Tetrahedron letters, 2000-09, Vol.41 (36), p.7013-7016

2000

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Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (3), p.313-318

1999

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The synthesis of (2S,4S,5S) -5-(N-BOC)-amino-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid lactone, an hydroxyethylene dipeptide isostere precusor

Tetrahedron letters, 1989, Vol.30 (4), p.415-418

1989

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Amidines as amide bond replacements in VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2323-2326

2004

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Total synthesis of (+)-demethyldysidenin and (-)-demethylisodysidenin, hexachlorinated amino acids from the marine sponge Dysidea herbacea. Assignment of absolute stereochemistry

Journal of the American Chemical Society, 1985-01, Vol.107 (1), p.199-203

1985

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Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.153

2002

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A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence

The Journal of pharmacology and experimental therapeutics, 2003-09, Vol.306 (3), p.903

2003

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A Small Molecule α 4 β 1 /α 4 β 7 Antagonist Differentiates between the Low-Affinity States of α 4 β 1 and α 4 β 7 : Characterization of Divalent Cation Dependence

The Journal of pharmacology and experimental therapeutics, 2003-09, Vol.306 (3), p.903-913

2003

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Molecular Basis for p38 Protein Kinase Inhibitor Specificity

Biochemistry (Easton), 1998-11, Vol.37 (47), p.16573-16581

1998

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α 4 β 7 /α 4 β 1 Dual Integrin Antagonists Block α 4 β 7 -Dependent Adhesion under Shear Flow

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.153-162

2002

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CorrigendumCorrigendum to “The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists”[Bioorg. Med. Chem. Lett. 12 (2002) 611]

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1695-1695

2002

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The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonists

Bioorganic & medicinal chemistry letters, 1996-04, Vol.6 (8), p.923-928

1996

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Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

N-(3-Phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonists

Identification of Unique VLA-4 Antagonists from a Combinatorial Library

N-(Arylacetyl)-biphenylalanines as Potent VLA-4 Antagonists

N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonists

Potent, orally absorbed glucagon receptor antagonists

A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor

N-Aryl-prolyl-dipeptides as potent antagonists of VLA-4

Substituted Imidazoles as Glucagon Receptor Antagonists

Pyrroles and other heterocycles as inhibitors of P38 kinase

Total synthesis of (.+-.)-dysidin, a marine metabolite containing an N-acyl-O-methyltetramic acid

Total synthesis of halogenated monoterpene marine natural products via the Diels-Alder reaction

Deprotection of N- tert-butoxycarbonyl (Boc) groups in the presence of tert-butyl esters

Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis

The synthesis of (2S,4S,5S) -5-(N-BOC)-amino-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid lactone, an hydroxyethylene dipeptide isostere precusor

Amidines as amide bond replacements in VLA-4 antagonists

Total synthesis of (+)-demethyldysidenin and (-)-demethylisodysidenin, hexachlorinated amino acids from the marine sponge Dysidea herbacea. Assignment of absolute stereochemistry

Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow

A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence

A Small Molecule α 4 β 1 /α 4 β 7 Antagonist Differentiates between the Low-Affinity States of α 4 β 1 and α 4 β 7 : Characterization of Divalent Cation Dependence

Molecular Basis for p38 Protein Kinase Inhibitor Specificity

α 4 β 7 /α 4 β 1 Dual Integrin Antagonists Block α 4 β 7 -Dependent Adhesion under Shear Flow

CorrigendumCorrigendum to “The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists”[Bioorg. Med. Chem. Lett. 12 (2002) 611]

The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonists

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