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A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

Science translational medicine, 2012-10, Vol.4 (156), p.156ra139

2012

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Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9407-9416

2007

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Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice

American journal of physiology: Gastrointestinal and liver physiology, 2019-06, Vol.316 (6), p.G816-G825

2019

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Heat Shock Protein 70 Inhibits Apoptosis in Cancer Cells Through Simultaneous and Independent Mechanisms

Gastroenterology (New York, N.Y. 1943), 2009-05, Vol.136 (5), p.1772-1782

2009

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Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models

JCI insight, 2022-01, Vol.7 (2)

2022

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Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors

American journal of physiology: Gastrointestinal and liver physiology, 2011-06, Vol.300 (6), p.G948-G955

2011

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New insights into the pathogenesis of pancreatitis

Current opinion in gastroenterology, 2013-09, Vol.29 (5), p.523-530

2013

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Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis

Gut, 2018-04, Vol.67 (4), p.600

2018

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Cerulein-Induced Chronic Pancreatitis Does Not Require Intra-Acinar Activation of Trypsinogen in Mice

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.1076-1085.e2

2013

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Endoplasmic Reticulum Stress Is Chronically Activated in Chronic Pancreatitis

The Journal of biological chemistry, 2014-10, Vol.289 (40), p.27551-27561

2014

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Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Laboratory investigation, 2015-06, Vol.95 (6), p.648-659

2015

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Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling

American journal of physiology: Gastrointestinal and liver physiology, 2022-10, Vol.323 (4), p.G375-G386

2022

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Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2022-06, Vol.22 (5), p.553-563

2022

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Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion

Gut, 2007-07, Vol.56 (7), p.958-964

2007

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Insulin degradation by acinar cell proteases creates a dysfunctional environment for human islets before/after transplantation: benefits of α-1 antitrypsin treatment

Transplantation, 2011-12, Vol.92 (11), p.1222-1230

2011

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TRAIL and Triptolide: An Effective Combination that Induces Apoptosis in Pancreatic Cancer Cells

Journal of gastrointestinal surgery, 2010-02, Vol.14 (2), p.252-260

2010

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Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis

American journal of physiology: Gastrointestinal and liver physiology, 2009-05, Vol.296 (5), p.G1040-G1046

2009

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Hepatotoxicity of Eupatorium adenophorum to rats

Toxicon (Oxford), 2000-02, Vol.38 (2), p.309-314

2000

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JAK-2 downregulation sensitizes pancreatic cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell death

Journal of the American College of Surgeons, 2012-09, Vol.215 (3), p.S135-S135

2012

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SIRT1 downregulation: A novel therapeutic strategy for pancreatobiliary cancers

Journal of the American College of Surgeons, 2010, Vol.211 (3), p.S125-S126

2010

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P33. HSP70 Inhibition Sensitizes to Trail Induced Apoptotic Cell Death in Pancreatic Cancer Cells

The Journal of surgical research, 2008, Vol.144 (2), p.448-448

2008

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QS308. HSP70 Inhibition Sensitizes to TRAIL Induced Apoptotic Cell Death in Pancreatic Cancer Cells

The Journal of surgical research, 2008, Vol.144 (2), p.389-389

2008

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P32. Myricetin a Novel Natural Antineoplastic Agent Decreases Progression of Human Pancreatic Cancer Via Inhibition of Akt Kinase and ERK Pathways

The Journal of surgical research, 2008, Vol.144 (2), p.448-448

2008

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55. Myricetin a Novel Natural Antineoplastic Agent Decreases Progression of Human Pancreatic Cancer Via Inhibition of Akt Kinase and Erk Pathways

The Journal of surgical research, 2008, Vol.144 (2), p.200-200

2008

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Combined therapy with anti-death receptor-5 antibody and triptolide induces apoptosis in pancreatic cancer cells

Journal of the American College of Surgeons, 2008, Vol.207 (3), p.S102-S102

2008

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A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70

Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice

Heat Shock Protein 70 Inhibits Apoptosis in Cancer Cells Through Simultaneous and Independent Mechanisms

Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models

Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors

New insights into the pathogenesis of pancreatitis

Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis

Cerulein-Induced Chronic Pancreatitis Does Not Require Intra-Acinar Activation of Trypsinogen in Mice

Endoplasmic Reticulum Stress Is Chronically Activated in Chronic Pancreatitis

Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling

Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation

Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion

Insulin degradation by acinar cell proteases creates a dysfunctional environment for human islets before/after transplantation: benefits of α-1 antitrypsin treatment

TRAIL and Triptolide: An Effective Combination that Induces Apoptosis in Pancreatic Cancer Cells

Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis

Hepatotoxicity of Eupatorium adenophorum to rats

JAK-2 downregulation sensitizes pancreatic cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell death

SIRT1 downregulation: A novel therapeutic strategy for pancreatobiliary cancers

P33. HSP70 Inhibition Sensitizes to Trail Induced Apoptotic Cell Death in Pancreatic Cancer Cells

QS308. HSP70 Inhibition Sensitizes to TRAIL Induced Apoptotic Cell Death in Pancreatic Cancer Cells

P32. Myricetin a Novel Natural Antineoplastic Agent Decreases Progression of Human Pancreatic Cancer Via Inhibition of Akt Kinase and ERK Pathways

55. Myricetin a Novel Natural Antineoplastic Agent Decreases Progression of Human Pancreatic Cancer Via Inhibition of Akt Kinase and Erk Pathways

Combined therapy with anti-death receptor-5 antibody and triptolide induces apoptosis in pancreatic cancer cells

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