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Iron( iii ) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activity

New journal of chemistry, 2018, Vol.42 (10), p.8074-8087

2018

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Antiglioma activity of GoPI-sugar, a novel gold(I)–phosphole inhibitor: Chemical synthesis, mechanistic studies, and effectiveness in vivo

Biochimica et biophysica acta, 2014-08, Vol.1844 (8), p.1415-1426

2014

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2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.548-565

2001

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A Prodrug Form of a Plasmodium falciparum Glutathione Reductase Inhibitor Conjugated with a 4-Anilinoquinoline

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4268-4276

2001

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Trypanosoma cruzi Prolyl Oligopeptidase Tc80 Is Involved in Nonphagocytic Mammalian Cell Invasion by Trypomastigotes

The Journal of biological chemistry, 2001-12, Vol.276 (50), p.47078-47086

2001

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Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2283-2292

2006

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Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

PLoS medicine, 2007-06, Vol.4 (6), p.e206-e206

2007

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Interactions of the antimalarial drug methylene blue with methemoglobin and heme targets in Plasmodium falciparum: a physico-biochemical study

Antioxidants & redox signaling, 2012-08, Vol.17 (4), p.544

2012

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752 INHIBITION OF HEPATITS C VIRUS ENTRY BY A PLANT-DERIVED FLAVONE

Journal of hepatology, 2010, Vol.52, p.S293-S293

2010

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Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases

Angewandte Chemie (International ed.), 2006-03, Vol.45 (12), p.1881-1886

2006

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5-Substituted Tetrazoles as Bioisosteres of Carboxylic Acids. Bioisosterism and Mechanistic Studies on Glutathione Reductase Inhibitors as Antimalarials

Journal of medicinal chemistry, 2004-11, Vol.47 (24), p.5972-5983

2004

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The conserved redox-sensitive cysteine residue of the DNA-binding region in the c-Rel protein is involved in the regulation of the phosphorylation of the protein

Biochemical journal, 2000-12, Vol.352 Pt 2 (2), p.583-591

2000

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Antiplasmodial Activity and Cytotoxicity of Bis-, Tris-, and Tetraquinolines with Linear or Cyclic Amino Linkers

Journal of medicinal chemistry, 2001-05, Vol.44 (11), p.1658-1665

2001

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Bromination Studies of the 2,3-Dimethylnaphthazarin Core Allowing Easy Access to Naphthazarin Derivatives

Journal of organic chemistry, 2001-08, Vol.66 (16), p.5616-5619

2001

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Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase

Organic & biomolecular chemistry, 2012-06, Vol.10 (24), p.4795-4806

2012

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Mechanistic Studies on a Novel, Highly Potent Gold-Phosphole Inhibitor of Human Glutathione Reductase

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20628-20637

2005

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Potent and specific inhibitors of trypanothione reductase from Trypanosoma cruzi: bis(2-aminodiphenylsulfides) for fluorescent labeling studies

Bioorganic & medicinal chemistry, 2001-04, Vol.9 (4), p.837-846

2001

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Antimalarial, Antitrypanosomal, and Antileishmanial Activities and Cytotoxicity of Bis(9-amino-6-chloro-2-methoxyacridines): Influence of the Linker

Journal of medicinal chemistry, 2000-07, Vol.43 (14), p.2646-2654

2000

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Synthesis of 5-Nitro-2-furancarbohydrazides and Their cis-Diamminedichloroplatinum Complexes as Bitopic and Irreversible Human Thioredoxin Reductase Inhibitors

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.7024-7039

2005

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Irreversible Inactivation of Trypanothione Reductase by Unsaturated Mannich Bases: A Divinyl Ketone as Key Intermediate

Journal of medicinal chemistry, 2005-11, Vol.48 (23), p.7400-7410

2005

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Iron(iii) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activityElectronic supplementary information (ESI) available: Absorption spectrophotometric titrations of the ligands and the ferric complexes; ESI-MS characterization; oxidation kinetics of the ligands monitored by absorption spectrophotometry; ICP-MS data. See DOI: 10.1039/c7nj04867j

2018-05

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Mechanism-Based Inactivation of Thioredoxin Reductase from Plasmodium falciparum by Mannich Bases. Implication for Cytotoxicity

Biochemistry (Easton), 2003-11, Vol.42 (45), p.13319-13330

2003

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New potent inhibitors of trypanothione reductase from Trypanosoma cruzi in the 2-aminodiphenylsulfide series

European journal of medicinal chemistry, 1997, Vol.32 (1), p.39-52

1997

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Trypanothione reductase inhibition/trypanocidal activity relationships in a 1,4-bis(3-aminopropyl)piperazine series

Bioorganic & medicinal chemistry, 2000, Vol.8 (1), p.95-103

2000

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Double-drug development against antioxidant enzymes from Plasmodium falciparum

Redox report : communications in free radical research, 2003-01, Vol.8 (5), p.280-283

2003

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Iron( iii ) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activity

Antiglioma activity of GoPI-sugar, a novel gold(I)–phosphole inhibitor: Chemical synthesis, mechanistic studies, and effectiveness in vivo

2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

A Prodrug Form of a Plasmodium falciparum Glutathione Reductase Inhibitor Conjugated with a 4-Anilinoquinoline

Trypanosoma cruzi Prolyl Oligopeptidase Tc80 Is Involved in Nonphagocytic Mammalian Cell Invasion by Trypomastigotes

Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

Interactions of the antimalarial drug methylene blue with methemoglobin and heme targets in Plasmodium falciparum: a physico-biochemical study

752 INHIBITION OF HEPATITS C VIRUS ENTRY BY A PLANT-DERIVED FLAVONE

Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases

5-Substituted Tetrazoles as Bioisosteres of Carboxylic Acids. Bioisosterism and Mechanistic Studies on Glutathione Reductase Inhibitors as Antimalarials

The conserved redox-sensitive cysteine residue of the DNA-binding region in the c-Rel protein is involved in the regulation of the phosphorylation of the protein

Antiplasmodial Activity and Cytotoxicity of Bis-, Tris-, and Tetraquinolines with Linear or Cyclic Amino Linkers

Bromination Studies of the 2,3-Dimethylnaphthazarin Core Allowing Easy Access to Naphthazarin Derivatives

Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase

Mechanistic Studies on a Novel, Highly Potent Gold-Phosphole Inhibitor of Human Glutathione Reductase

Potent and specific inhibitors of trypanothione reductase from Trypanosoma cruzi: bis(2-aminodiphenylsulfides) for fluorescent labeling studies

Antimalarial, Antitrypanosomal, and Antileishmanial Activities and Cytotoxicity of Bis(9-amino-6-chloro-2-methoxyacridines): Influence of the Linker

Synthesis of 5-Nitro-2-furancarbohydrazides and Their cis-Diamminedichloroplatinum Complexes as Bitopic and Irreversible Human Thioredoxin Reductase Inhibitors

Irreversible Inactivation of Trypanothione Reductase by Unsaturated Mannich Bases: A Divinyl Ketone as Key Intermediate

Mechanism-Based Inactivation of Thioredoxin Reductase from Plasmodium falciparum by Mannich Bases. Implication for Cytotoxicity

New potent inhibitors of trypanothione reductase from Trypanosoma cruzi in the 2-aminodiphenylsulfide series

Trypanothione reductase inhibition/trypanocidal activity relationships in a 1,4-bis(3-aminopropyl)piperazine series

Double-drug development against antioxidant enzymes from Plasmodium falciparum

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