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An allylic ketyl radical intermediate in clostridial amino-acid fermentation

Nature, 2008-03, Vol.452 (7184), p.239-242

2008

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Molecular and Functional Analysis of Nicotinate Catabolism in Eubacterium barkeri

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (33), p.12341-12346

2006

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Complete Stereochemistry of the Enzymatic Dehydration of 4-Hydroxybutyryl Coenzyme A to Crotonyl Coenzyme A

Angewandte Chemie (International ed.), 2008-04, Vol.47 (17), p.3254-3257

2008

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α-Methylacyl-CoA racemase - an 'obscure' metabolic enzyme takes centre stage

The FEBS journal, 2008-03, Vol.275 (6), p.1089-1102

2008

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Synthesis and use of isotope-labelled substrates for a mechanistic study on human alpha-methylacyl-CoA racemase 1A (AMACR; P504S)

Organic & biomolecular chemistry, 2009-01, Vol.7 (3), p.543-552

2009

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Unexpected stereoselective exchange of straight-chain fatty acyl-CoA alpha-protons by human alpha-methylacyl-CoA racemase 1A (P504S)

Chemical communications (Cambridge, England), 2010-01, Vol.46 (19), p.3348-3350

2010

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Unexpected stereoselective exchange of straight-chain fatty acyl-CoA α-protons by human α-methylacyl-CoA racemase 1A (P504S)Electronic supplementary information (ESI) available: Synthetic methods, compound characterisation data and enzyme kinetic plots. See DOI: 10.1039/c002509g

2010-05

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Der stereochemische Verlauf der enzymatischen Wassereliminierung von 4-Hydroxybutyryl-Coenzym A zu Crotonyl-Coenzym A

Angewandte Chemie, 2008-04, Vol.120 (17), p.3298-3301

2008

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Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B12-Dependent Glutamate Mutase from Clostridium cochlearium

Biochemistry (Easton), 1998-03, Vol.37 (12), p.4105-4113

1998

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[alpha]-Methylacyl-CoA racemase - an 'obscure' metabolic enzyme takes centre stage

The FEBS journal, 2008-03, Vol.275 (6), p.1089

2008

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Der stereochemische Verlauf der enzymatischen Wassereliminierung von 4‐Hydroxybutyryl‐Coenzym A zu Crotonyl‐Coenzym A

Angewandte Chemie, 2008-04, Vol.120 (17), p.3298-3301

2008

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Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B 12 -Dependent Glutamate Mutase from Clostridium c ochlearium

Biochemistry (Easton), 1998-03, Vol.37 (12), p.4105-4113

1998

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Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B12-Dependent Glutamate Mutase from Clostridium c ochlearium

Biochemistry (Easton), 1998-03, Vol.37 (12), p.4105-4113

1998

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Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

Nature immunology, 2022-02, Vol.23 (2), p.210-216

2022

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Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

Nature communications, 2024-04, Vol.15 (1), p.3315-3315, Article 3315

2024

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Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9184-9204

2017

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Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.5060-5073

2019

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estimate of the number of tropical tree species

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (24), p.7472-7477

2015

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Phylogenetic classification of the world’s tropical forests

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (8), p.1837-1842

2018

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Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

Nature communications, 2022-01, Vol.13 (1), p.139-20, Article 139

2022

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Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

Cell reports (Cambridge), 2020-02, Vol.30 (6), p.1798-1810.e4

2020

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Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

Haematologica (Roma), 2015-08, Vol.100 (8), p.1076

2015

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An allylic ketyl radical intermediate in clostridial amino-acid fermentation

Molecular and Functional Analysis of Nicotinate Catabolism in Eubacterium barkeri

Complete Stereochemistry of the Enzymatic Dehydration of 4-Hydroxybutyryl Coenzyme A to Crotonyl Coenzyme A

α-Methylacyl-CoA racemase - an 'obscure' metabolic enzyme takes centre stage

Synthesis and use of isotope-labelled substrates for a mechanistic study on human alpha-methylacyl-CoA racemase 1A (AMACR; P504S)

Unexpected stereoselective exchange of straight-chain fatty acyl-CoA alpha-protons by human alpha-methylacyl-CoA racemase 1A (P504S)

Unexpected stereoselective exchange of straight-chain fatty acyl-CoA α-protons by human α-methylacyl-CoA racemase 1A (P504S)Electronic supplementary information (ESI) available: Synthetic methods, compound characterisation data and enzyme kinetic plots. See DOI: 10.1039/c002509g

Der stereochemische Verlauf der enzymatischen Wassereliminierung von 4-Hydroxybutyryl-Coenzym A zu Crotonyl-Coenzym A

Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B12-Dependent Glutamate Mutase from Clostridium cochlearium

[alpha]-Methylacyl-CoA racemase - an 'obscure' metabolic enzyme takes centre stage

Der stereochemische Verlauf der enzymatischen Wassereliminierung von 4‐Hydroxybutyryl‐Coenzym A zu Crotonyl‐Coenzym A

Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B 12 -Dependent Glutamate Mutase from Clostridium c ochlearium

Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B12-Dependent Glutamate Mutase from Clostridium c ochlearium

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

estimate of the number of tropical tree species

SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants

Phylogenetic classification of the world’s tropical forests

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells

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