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Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

Nature (London), 2009-12, Vol.462 (7276), p.1070-1074

2009

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An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2485-2494

2010

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Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

Nature medicine, 2011-07, Vol.17 (7), p.875-882

2011

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Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (46), p.19503-19508

2009

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Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

Cancer cell, 2011-09, Vol.20 (3), p.400-413

2011

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Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non―Small Cell Lung Cancer

Clinical cancer research, 2012-09, Vol.18 (18), p.4973-4985

2012

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A dual role for the immune response in a mouse model of inflammation-associated lung cancer

The Journal of clinical investigation, 2011-06, Vol.121 (6), p.2436-2446

2011

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Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (23), p.9827-9836

2010

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Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells

Cell stem cell, 2010-07, Vol.7 (1), p.127-133

2010

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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

Cancer cell, 2006-06, Vol.9 (6), p.485-495

2006

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Epidermal Growth Factor Receptor Variant III Mutations in Lung Tumorigenesis and Sensitivity to Tyrosine Kinase Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7817-7822

2006

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Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (14), p.5827-5838

2008

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Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (10), p.4933-4939

2007

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Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin

Clinical cancer research, 2008-10, Vol.14 (20), p.6478-6486

2008

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PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor

Clinical cancer research, 2015-03, Vol.21 (6), p.1487-1496

2015

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A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

Cell, 2009-05, Vol.137 (5), p.835-848

2009

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A dual role for the immune response in a mouse model of inflammation-associated lung cancer

The Journal of clinical investigation, 2011-06, Vol.121 (6), p.2436-2446

2011

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Preparation, solution characteristics and displacement performances of a novel acrylamide copolymer for enhanced oil recovery (EOR)

Polymer bulletin (Berlin, Germany), 2018-03, Vol.75 (3), p.1001-1011

2018

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β-catenin contributes to lung tumor development induced by EGFR mutations

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (20), p.5891-5902

2014

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HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (2), p.474-479

2009

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Abstract A1-52: Identification of drug-sensitive Notch receptor alterations in human breast cancer

Cancer research (Chicago, Ill.), 2015-11, Vol.75 (22_Supplement_1), p.A1-A1-52

2015

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TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity

Oncogene, 2010-03, Vol.29 (11), p.1588-1597

2010

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Abstract 968: β-catenin plays an important role in lung tumor development induced by EGFR mutations

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.968-968

2014

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Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non―Small Cell Lung Cancer

LKB1 modulates lung cancer differentiation and metastasis

A dual role for the immune response in a mouse model of inflammation-associated lung cancer

Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene

Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy

Epidermal Growth Factor Receptor Variant III Mutations in Lung Tumorigenesis and Sensitivity to Tyrosine Kinase Inhibitors

Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance

Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models

Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin

PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

A dual role for the immune response in a mouse model of inflammation-associated lung cancer

Preparation, solution characteristics and displacement performances of a novel acrylamide copolymer for enhanced oil recovery (EOR)

β-catenin contributes to lung tumor development induced by EGFR mutations

HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

Abstract A1-52: Identification of drug-sensitive Notch receptor alterations in human breast cancer

TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity

Abstract 968: β-catenin plays an important role in lung tumor development induced by EGFR mutations

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