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Determinants of dopaminergic neuron loss in Parkinson's disease

The FEBS journal, 2018-10, Vol.285 (19), p.3657-3668

Surmeier, Dalton James

2018

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Structural Assessment of Agonist Efficacy in the μ‑Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns

Journal of chemical information and modeling, 2021-03, Vol.61 (3), p.1251-1274

2021

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Development of selective androgen receptor modulators (SARMs)

Molecular and cellular endocrinology, 2018-04, Vol.465, p.134-142

2018

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Beyond Just Connectivity — Neuronal Activity Drives α‐Synuclein Pathology

Movement disorders, 2021-07, Vol.36 (7), p.1487-1488

Surmeier, Dalton James

2021

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Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions

PLoS computational biology, 2020-04, Vol.16 (4), p.e1007818-e1007818

2020

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Revealing the Mechanism of Agonist-Mediated Cannabinoid Receptor 1 (CB1) Activation and Phospholipid-Mediated Allosteric Modulation

Journal of medicinal chemistry, 2019-06, Vol.62 (11), p.5638-5654

2019

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Communications with lab and POCT users

Practical laboratory medicine, 2021-05, Vol.25, p.e00223-e00223, Article e00223

Dalton, James

2021

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The long and winding road for selective androgen receptor modulators

British journal of clinical pharmacology, 2017-10, Vol.83 (10), p.2131-2133

Dalton, James T.

2017

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Androgen Receptor: A Complex Therapeutic Target for Breast Cancer

Cancers, 2016-12, Vol.8 (12), p.108

2016

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Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism

BMC bioinformatics, 2015-04, Vol.16 (1), p.124-124, Article 124

2015

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Statistics for the analysis of molecular dynamics simulations: providing P values for agonist-dependent GPCR activation

Scientific reports, 2020-11, Vol.10 (1), p.19942-19942, Article 19942

2020

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Selective Protonation of Acidic Residues Triggers Opsin Activation

The journal of physical chemistry. B, 2015-07, Vol.119 (30), p.9510-9519

2015

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Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma

Cell reports (Cambridge), 2014-04, Vol.7 (1), p.104-112

2014

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Distinct Dopamine D₂ Receptor Antagonists Differentially Impact D₂ Receptor Oligomerization

International journal of molecular sciences, 2019-04, Vol.20 (7), p.1686

2019

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An automated system for interrogating the evolution of microbial endosymbiosis

Lab on a chip, 2023-02, Vol.23 (4), p.671-683

2023

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Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial:mesenchymal stem cell signaling

PloS one, 2014-07, Vol.9 (7), p.e103202

2014

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Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions

Scientific reports, 2018-03, Vol.8 (1), p.4456-14, Article 4456

2018

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Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial

The lancet oncology, 2013-04, Vol.14 (4), p.335-345

2013

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Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand

Scientific reports, 2017-07, Vol.7 (1), p.4944-14, Article 4944

2017

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C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

Nature (London), 2014-02, Vol.506 (7489), p.451-455

2014

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Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

Nature genetics, 2013-06, Vol.45 (6), p.602-612

2013

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Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Acta neuropathologica, 2016-06, Vol.131 (6), p.833-845

2016

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Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer

eLife, 2017-08, Vol.6

2017

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Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

Journal of medicinal chemistry, 2009-03, Vol.52 (6), p.1701-1711

2009

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An evaluation of automated homology modelling methods at low target–template sequence similarity

Bioinformatics, 2007-08, Vol.23 (15), p.1901-1908

2007

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Determinants of dopaminergic neuron loss in Parkinson's disease

Structural Assessment of Agonist Efficacy in the μ‑Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns

Development of selective androgen receptor modulators (SARMs)

Beyond Just Connectivity — Neuronal Activity Drives α‐Synuclein Pathology

Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions

Revealing the Mechanism of Agonist-Mediated Cannabinoid Receptor 1 (CB1) Activation and Phospholipid-Mediated Allosteric Modulation

Communications with lab and POCT users

The long and winding road for selective androgen receptor modulators

Androgen Receptor: A Complex Therapeutic Target for Breast Cancer

Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism

Statistics for the analysis of molecular dynamics simulations: providing P values for agonist-dependent GPCR activation

Selective Protonation of Acidic Residues Triggers Opsin Activation

Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma

Distinct Dopamine D₂ Receptor Antagonists Differentially Impact D₂ Receptor Oligomerization

An automated system for interrogating the evolution of microbial endosymbiosis

Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial:mesenchymal stem cell signaling

Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions

Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer

Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

An evaluation of automated homology modelling methods at low target–template sequence similarity

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