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ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance

Communications biology, 2021-04, Vol.4 (1), p.497-497, Article 497

2021

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Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities

Journal of the American Chemical Society, 2021-03, Vol.143 (12), p.4714-4724

2021

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SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6104-6109

2008

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The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (19), p.5300-5309

2007

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Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (7), p.2053-2058

2009

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Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.973-978

2008

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Bioorganic & medicinal chemistry letters, 2008-03, Vol.18 (6), p.1859-1863

2008

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Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1168-1172

2009

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Amino acid derivatives as histone deacetylase inhibitors

Bioorganic & medicinal chemistry, 2008, Vol.18 (1), p.34-38

2008

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1859-1863

2008

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Response of human tumor cells of varying radiosensitivity and radiocurability to fractionated irradiation

Cancer research (Chicago, Ill.), 1999-10, Vol.59 (20), p.5365-5369

1999

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Abstract 944: exoSTING: An engineered exosome therapeutic that selectively delivers STING agonist to the tumor resident antigen-presenting cells resulting in improved tumor antigen-specific adaptive immune response

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.944-944

2019

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Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma

International journal of cancer, 2002-06, Vol.99 (5), p.764-768

2002

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Differing Responses of Nijmegen Breakage Syndrome and Ataxia Telangiectasia Cells to Ionizing Radiation

Radiation research, 2002-09, Vol.158 (3), p.319-326

2002

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ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation

Oncogene, 2000-12, Vol.19 (54), p.6185-6193

2000

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Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines

Oncogene, 1995-11, Vol.11 (9), p.1885

1995

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC 1 inhibitors (SHI-1)

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (6), p.1859-1863

2008

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Response of dermal fibroblast cultures from patients with unusually severe responses to radiotherapy and from ataxia telangiectasia heterozygotes to fractionated radiation

Clinical cancer research, 1995-08, Vol.1 (8), p.785-790

1995

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Radiosensitivity of human biliary tract cancer cell lines in vitro

International journal of oncology, 1997-03

1997

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Differential sensitization of human tumor cells by ara-A to X irradiation and its relationship to inherent radioresponse

Radiation research, 1992-06, Vol.130 (3), p.303

1992

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In vitro radiosensitivity of human diploid fibroblasts derived from women with unusually sensitive clinical responses to definitive radiation therapy for breast cancer

Radiation research, 1990-02, Vol.121 (2), p.227

1990

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ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance

Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities

SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2)

The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors

Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer

Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization

Amino acid derivatives as histone deacetylase inhibitors

Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Response of human tumor cells of varying radiosensitivity and radiocurability to fractionated irradiation

Abstract 944: exoSTING: An engineered exosome therapeutic that selectively delivers STING agonist to the tumor resident antigen-presenting cells resulting in improved tumor antigen-specific adaptive immune response

Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma

Differing Responses of Nijmegen Breakage Syndrome and Ataxia Telangiectasia Cells to Ionizing Radiation

Abstract LB-062: Development of macromolecular prodrugs of BET-bromodomain inhibitors with superior anti-tumor efficacy that are T-cell sparing and devoid of systemic toxicity

Discovery of a 5 H -Benzo[4,5]cyclohepta[1,2- b ]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer

ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation

Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines

Phenylglycine and phenylalanine derivatives as potent and selective HDAC 1 inhibitors (SHI-1)

Response of dermal fibroblast cultures from patients with unusually severe responses to radiotherapy and from ataxia telangiectasia heterozygotes to fractionated radiation

Radiosensitivity of human biliary tract cancer cell lines in vitro

Differential sensitization of human tumor cells by ara-A to X irradiation and its relationship to inherent radioresponse

In vitro radiosensitivity of human diploid fibroblasts derived from women with unusually sensitive clinical responses to definitive radiation therapy for breast cancer

Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data

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