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The Chemistry Behind ADCs

Pharmaceuticals (Basel, Switzerland), 2021-05, Vol.14 (5), p.442

2021

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S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool

The Journal of pharmacology and experimental therapeutics, 2008-12, Vol.327 (3), p.809-819

2008

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Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa)

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.3897-3910

2021

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In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda receptors antagonist

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P612-P613

2015

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P4‐172: S 44858, a positive allosteric modulator of ampa receptors and GluN2B selective nmda receptors antagonist, prevents the disruption of synaptic plasticity induced by Aβ oligomers

Alzheimer's & dementia, 2015-07, Vol.11 (7S_Part_18), p.P845-P845

2015

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P2‐311: In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non‐competitive nmda receptors antagonist

Alzheimer's & dementia, 2015-07, Vol.11 (7S_Part_13), p.P612-P613

2015

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S 44858, a positive allosteric modulator of ampa receptors and GluN2B selective nmda receptors antagonist, prevents the disruption of synaptic plasticity induced by Aβ oligomers

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P845-P845

2015

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P2‐312: In vivo characterization of s44858, a positive allosteric modulator of ampa receptors and GluN2B selective non‐competitive nmda antagonist

Alzheimer's & dementia, 2015-07, Vol.11 (7S_Part_13), p.P613-P613

2015

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In vivo characterization of s44858, a positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda antagonist

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P613-P613

2015

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DRUG FOCUS: S 18986: A Positive Allosteric Modulator of AMPA‐Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer

CNS neuroscience & therapeutics, 2010-10, Vol.16 (5), p.e193-e212

2010

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P1-406 S 18986, positive allosteric modulator of AMPA receptors as a novel cognition enhancer in rodents

Neurobiology of aging, 2004-07, Vol.25, p.S214-S214

2004

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Structure−Activity Relationships in a Series of 2(1H)-Quinolones Bearing Different Acidic Function in the 3-Position: 6,7-Dichloro-2(1H)-oxoquinoline-3-phosphonic Acid, a New Potent and Selective AMPA/Kainate Antagonist with Neuroprotective Properties

Journal of medicinal chemistry, 1996-01, Vol.39 (1), p.197-206

1996

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Asymmetric Synthesis. 39. Synthesis of 2-(1-Aminoalkyl)piperidines via 2-Cyano-6-phenyl Oxazolopiperidine

Journal of organic chemistry, 1996-09, Vol.61 (19), p.6700-6705

1996

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Structure-activity relationships in a series of 3-sulfonylamino-2-(1 H)-quinolones, as new AMPA/Kainate and glycine antagonists

Bioorganic & medicinal chemistry, 1995-02, Vol.3 (2), p.129-141

1995

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Novel quinolinone-phosphonic acid AMPA antagonists devoid of nephrotoxicity

Farmaco (Società chimica italiana : 1989), 2002-10, Vol.57 (10), p.787-802

2002

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Photoactive C16-C21 fragmentation of catharanthine

Tetrahedron letters, 1991-06, Vol.32 (26), p.3035-3038

1991

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Asymmetric Synthesis. 39. 1 Synthesis of 2-(1-Aminoalkyl)piperidines via 2-Cyano-6-phenyl Oxazolopiperidine

Journal of organic chemistry, 1996-01, Vol.61 (19), p.6700-6705

1996

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Oxidative fragmentation of catharanthine by dichlorodicyanoquinone

Journal of organic chemistry, 1991-03, Vol.56 (5), p.1689-1692

1991

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Synthesis of triazolo- and tetrazoloquinoline derivatives with antithrombotic activity

Heterocycles, 1989, Vol.28 (2), p.1085-1099

1989

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Novel Quinolinone-Phosphonic Acid AMPA Antagonists Devoid of Nephrotoxicity

ChemInform, 2003-02, Vol.34 (8), p.no-no

2003

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The Chemistry Behind ADCs

S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool

Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa)

In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda receptors antagonist

P4‐172: S 44858, a positive allosteric modulator of ampa receptors and GluN2B selective nmda receptors antagonist, prevents the disruption of synaptic plasticity induced by Aβ oligomers

P2‐311: In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non‐competitive nmda receptors antagonist

S 44858, a positive allosteric modulator of ampa receptors and GluN2B selective nmda receptors antagonist, prevents the disruption of synaptic plasticity induced by Aβ oligomers

P2‐312: In vivo characterization of s44858, a positive allosteric modulator of ampa receptors and GluN2B selective non‐competitive nmda antagonist

In vivo characterization of s44858, a positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda antagonist

DRUG FOCUS: S 18986: A Positive Allosteric Modulator of AMPA‐Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer

P1-406 S 18986, positive allosteric modulator of AMPA receptors as a novel cognition enhancer in rodents

Structure−Activity Relationships in a Series of 2(1H)-Quinolones Bearing Different Acidic Function in the 3-Position: 6,7-Dichloro-2(1H)-oxoquinoline-3-phosphonic Acid, a New Potent and Selective AMPA/Kainate Antagonist with Neuroprotective Properties

Asymmetric Synthesis. 39. Synthesis of 2-(1-Aminoalkyl)piperidines via 2-Cyano-6-phenyl Oxazolopiperidine

Structure-activity relationships in a series of 3-sulfonylamino-2-(1 H)-quinolones, as new AMPA/Kainate and glycine antagonists

Novel quinolinone-phosphonic acid AMPA antagonists devoid of nephrotoxicity

Photoactive C16-C21 fragmentation of catharanthine

Asymmetric Synthesis. 39. 1 Synthesis of 2-(1-Aminoalkyl)piperidines via 2-Cyano-6-phenyl Oxazolopiperidine

Oxidative fragmentation of catharanthine by dichlorodicyanoquinone

Synthesis of triazolo- and tetrazoloquinoline derivatives with antithrombotic activity

Novel Quinolinone-Phosphonic Acid AMPA Antagonists Devoid of Nephrotoxicity

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