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AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington’s disease

Gene therapy, 2017-10, Vol.24 (10), p.630-639

2017

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BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

Translational psychiatry, 2013-04, Vol.3 (4), p.e253-e253

2013

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Formation of hippocampal mHTT aggregates leads to impaired spatial memory, hippocampal activation and adult neurogenesis

Neurobiology of disease, 2017-06, Vol.102, p.105-112

2017

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Gene transfer engineering for astrocyte-specific silencing in the CNS

Gene therapy, 2015-10, Vol.22 (10), p.830-839

2015

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Gene editing as a therapeutic strategy for spinocerebellar ataxia type-3

Revue neurologique, 2024-05, Vol.180 (5), p.378-382

Déglon, N.

2024

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Implication of the JNK pathway in a rat model of Huntington's disease

Experimental neurology, 2009, Vol.215 (1), p.191-200

2009

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α-Synucleinopathy and Selective Dopaminergic Neuron Loss in a Rat Lentiviral-Based Model of Parkinson's Disease

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10813-10818

2002

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Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: Results of a phase I study

Human gene therapy, 2004-10, Vol.15 (10), p.968-975

2004

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Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease

Neurobiology of disease, 2004-11, Vol.17 (2), p.283-289

2004

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Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's Disease

Neurobiology of disease, 2001-06, Vol.8 (3), p.433-446

2001

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Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease

Human gene therapy, 2002-11, Vol.13 (16), p.1981-1990

2002

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Complete and Long-Term Rescue of Lesioned Adult Motoneurons by Lentiviral-Mediated Expression of Glial Cell Line-Derived Neurotrophic Factor in the Facial Nucleus

The Journal of neuroscience, 2000-08, Vol.20 (15), p.5587-5593

2000

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Isolation of Multipotent Neural Precursors Residing in the Cortex of the Adult Human Brain

Experimental neurology, 2001-07, Vol.170 (1), p.48-62

2001

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Grafts of Adenosine-Releasing Cells Suppress Seizures in Kindling Epilepsy

Proceedings of the National Academy of Sciences - PNAS, 2001-06, Vol.98 (13), p.7611-7616

2001

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Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF

Human gene therapy, 2000-08, Vol.11 (12), p.1723-1729

2000

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Lentiviral Vectors as a Gene Delivery System in the Mouse Midbrain: Cellular and Behavioral Improvements in a 6-OHDA Model of Parkinson's Disease Using GDNF

Experimental neurology, 2000-07, Vol.164 (1), p.15-24

2000

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Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

Human gene therapy, 2000, Vol.11 (1), p.179-190

2000

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Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients

Nature medicine, 1996-06, Vol.2 (6), p.696-699

1996

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Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado―Joseph disease

Brain (London, England : 1878), 2012-08, Vol.135 (Pt 8), p.2428-2439

2012

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Lentiviral Gene Transfer to the Nonhuman Primate Brain

Experimental neurology, 1999-11, Vol.160 (1), p.1-16

1999

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Gene Transfer into Neurons from Hippocampal Slices: Comparison of Recombinant Semliki Forest Virus, Adenovirus, Adeno-Associated Virus, Lentivirus, and Measles Virus

Molecular and cellular neuroscience, 2001-05, Vol.17 (5), p.855-871

2001

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Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice

Brain (London, England : 1878), 2024-08, Vol.147 (8), p.2691-2705

2024

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Viral vectors as tools to model and treat neurodegenerative disorders

The journal of gene medicine, 2005-05, Vol.7 (5), p.530-539

2005

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Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions

Human gene therapy, 2004-07, Vol.15 (7), p.669-680

2004

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Neurobiological relationships between astroglial Cx43 and stress-related responses

European neuropsychopharmacology, 2019, Vol.29, p.S492-S493

2019

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AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington’s disease

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

Formation of hippocampal mHTT aggregates leads to impaired spatial memory, hippocampal activation and adult neurogenesis

Gene transfer engineering for astrocyte-specific silencing in the CNS

Gene editing as a therapeutic strategy for spinocerebellar ataxia type-3

Implication of the JNK pathway in a rat model of Huntington's disease

α-Synucleinopathy and Selective Dopaminergic Neuron Loss in a Rat Lentiviral-Based Model of Parkinson's Disease

Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: Results of a phase I study

Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease

Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's Disease

Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease

Complete and Long-Term Rescue of Lesioned Adult Motoneurons by Lentiviral-Mediated Expression of Glial Cell Line-Derived Neurotrophic Factor in the Facial Nucleus

Isolation of Multipotent Neural Precursors Residing in the Cortex of the Adult Human Brain

Grafts of Adenosine-Releasing Cells Suppress Seizures in Kindling Epilepsy

Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF

Lentiviral Vectors as a Gene Delivery System in the Mouse Midbrain: Cellular and Behavioral Improvements in a 6-OHDA Model of Parkinson's Disease Using GDNF

Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado―Joseph disease

Lentiviral Gene Transfer to the Nonhuman Primate Brain

Gene Transfer into Neurons from Hippocampal Slices: Comparison of Recombinant Semliki Forest Virus, Adenovirus, Adeno-Associated Virus, Lentivirus, and Measles Virus

Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice

Viral vectors as tools to model and treat neurodegenerative disorders

Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions

Neurobiological relationships between astroglial Cx43 and stress-related responses

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