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Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

The Journal of neuroscience, 2010-08, Vol.30 (32), p.10851-10859

2010

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Innovation in an E. coli evolution experiment is contingent on maintaining adaptive potential until competition subsides

PLoS genetics, 2018-04, Vol.14 (4), p.e1007348-e1007348

2018

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Heterogeneity of Matrin 3 in the developing and aging murine central nervous system

Journal of comparative neurology (1911), 2016-10, Vol.524 (14), p.2740-2752

2016

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Therapeutic and diagnostic challenges for frontotemporal dementia

Frontiers in aging neuroscience, 2014-08, Vol.6, p.204-204

2014

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Promoter recruitment drives the emergence of proto-genes in a long-term evolution experiment with Escherichia coli

PLoS biology, 2024-05, Vol.22 (5), p.e3002418-e3002418

2024

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Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy

Acta neuropathologica, 2013-07, Vol.126 (1), p.39-50

2013

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Neuronal sensitivity to TDP-43 overexpression is dependent on timing of induction

Acta neuropathologica, 2012-06, Vol.123 (6), p.807-823

2012

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Proteomic Techniques to Examine Neuronal Translational Dynamics

International journal of molecular sciences, 2019-07, Vol.20 (14), p.3524

2019

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Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission

Acta neuropathologica, 2015-08, Vol.130 (2), p.303-305

2015

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Understanding the role of progranulin in Alzheimer's disease

Nature medicine, 2014-10, Vol.20 (10), p.1099-1100

2014

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Divergent phenotypes in mutant TDP-43 transgenic mice highlight potential confounds in TDP-43 transgenic modeling

PloS one, 2014-01, Vol.9 (1), p.e86513

2014

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Studies of alternative isoforms provide insight into TDP-43 autoregulation and pathogenesis

RNA (Cambridge), 2015-08, Vol.21 (8), p.1419-1432

2015

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Review of “You're Looking At Me Like I Live Here And I Don't”

Journal of Alzheimer's disease, 2014-05, Vol.40 (4), p.1061-1062

2014

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Global Transcriptional Response of Methylorubrum extorquens to Formaldehyde Stress Expands the Role of EfgA and Is Distinct from Antibiotic Translational Inhibition

Microorganisms (Basel), 2021-02, Vol.9 (2), p.347

2021

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Changing perspectives on Alzheimer's disease: thinking outside the amyloid box

Journal of Alzheimer's disease, 2011-01, Vol.25 (4), p.571-581

2011

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Adapting to dementia in society: a challenge for our lifetimes and a charge for public health

Journal of Alzheimer's disease, 2014-01, Vol.42 (4), p.1151-1163

2014

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Through the amyloid gateway

The Lancet (British edition), 2012-12, Vol.380 (9858), p.1986-1987

2012

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Characterisation of alternative isoforms of TDP-43

Alzheimer's & dementia, 2011-07, Vol.7 (4), p.S752-S752

2011

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P4‐139: Characterisation of alternative isoforms of TDP‐43

Alzheimer's & dementia, 2011-07, Vol.7 (4S_Part_22), p.S752-S752

2011

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Describing the dying days of "Alzheimer's disease"

Journal of Alzheimer's disease, 2011-01, Vol.24 (1), p.11-13

2011

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P2-104 Factors influencing the development of taupathy in transgenic mice

Neurobiology of aging, 2004-07, Vol.25, p.S253-S253

D'Alton, Simon V.

2004

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Influence on phenotype of the postnatal developmental period in mice expressing human M337V TDP-43

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.P628-P629

2012

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S5‐02‐02: Lessons learned from emerging mouse models of TDP‐43 proteinopathy

Alzheimer's & dementia, 2012-07, Vol.8 (4S_Part_20), p.P725-P725

2012

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O4‐07‐06: Influence on phenotype of the postnatal developmental period in mice expressing human M337V TDP‐43

Alzheimer's & dementia, 2012-07, Vol.8 (4S_Part_17), p.P628-P629

2012

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Lessons learned from emerging mouse models of TDP-43 proteinopathy

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.P725-P725

2012

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Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

Innovation in an E. coli evolution experiment is contingent on maintaining adaptive potential until competition subsides

Heterogeneity of Matrin 3 in the developing and aging murine central nervous system

Therapeutic and diagnostic challenges for frontotemporal dementia

Promoter recruitment drives the emergence of proto-genes in a long-term evolution experiment with Escherichia coli

Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy

Neuronal sensitivity to TDP-43 overexpression is dependent on timing of induction

Proteomic Techniques to Examine Neuronal Translational Dynamics

Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission

Understanding the role of progranulin in Alzheimer's disease

Divergent phenotypes in mutant TDP-43 transgenic mice highlight potential confounds in TDP-43 transgenic modeling

Studies of alternative isoforms provide insight into TDP-43 autoregulation and pathogenesis

Review of “You're Looking At Me Like I Live Here And I Don't”

Global Transcriptional Response of Methylorubrum extorquens to Formaldehyde Stress Expands the Role of EfgA and Is Distinct from Antibiotic Translational Inhibition

Changing perspectives on Alzheimer's disease: thinking outside the amyloid box

Adapting to dementia in society: a challenge for our lifetimes and a charge for public health

Through the amyloid gateway

Characterisation of alternative isoforms of TDP-43

P4‐139: Characterisation of alternative isoforms of TDP‐43

Describing the dying days of "Alzheimer's disease"

P2-104 Factors influencing the development of taupathy in transgenic mice

Influence on phenotype of the postnatal developmental period in mice expressing human M337V TDP-43

S5‐02‐02: Lessons learned from emerging mouse models of TDP‐43 proteinopathy

O4‐07‐06: Influence on phenotype of the postnatal developmental period in mice expressing human M337V TDP‐43

Lessons learned from emerging mouse models of TDP-43 proteinopathy

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