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Design of angiotensin converting enzyme inhibitors

Nature medicine, 1999-10, Vol.5 (10), p.1110-1112

1999

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History of the Design of Captopril and Related Inhibitors of Angiotensin Converting Enzyme

Hypertension (Dallas, Tex. 1979), 1991-04, Vol.17 (4), p.589-592

1991

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Effects of different angiotensin-converting enzyme (ACE) inhibitors on ischemic isolated rat hearts: relationship between cardiac ACE inhibition and cardioprotection

The Journal of pharmacology and experimental therapeutics, 1991-06, Vol.257 (3), p.919

1991

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Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE)

British journal of clinical pharmacology, 1989, Vol.28 (S2), p.115S-131S

1989

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Enzymes of the Renin-Angiotensin System and their Inhibitors

Annual review of biochemistry, 1982-01, Vol.51 (1), p.283-308

1982

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Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

Biochemistry (Easton), 1977-12, Vol.16 (25), p.5484-5491

1977

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Differentiation of angiotensin-converting enzyme (ACE) inhibitors by their selective inhibition of ACE in physiologically important target organs

American journal of hypertension, 1989-04, Vol.2 (4), p.294-306

1989

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Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines

Journal of medicinal chemistry, 1988-06, Vol.31 (6), p.1148-1160

1988

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Design of novel inhibitors of aminopeptidases. Synthesis of peptide-derived diamino thiols and sulfur replacement analogs of bestatin

Journal of medicinal chemistry, 1988-11, Vol.31 (11), p.2199-2211

1988

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Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence

The Journal of biological chemistry, 1980-01, Vol.255 (2), p.401-407

1980

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Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung

Biochemical pharmacology, 1971-07, Vol.20 (7), p.1637-1648

1971

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Fosinopril, a Phosphinic Acid Inhibitor of Angiotensin I Converting Enzyme: In Vitro and Preclinical In Vivo Pharmacology

Journal of cardiovascular pharmacology, 1989-11, Vol.14 (5), p.730-736

1989

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Preclinical Pharmacology of Zofenopril, an Inhibitor of Angiotensin I Converting Enzyme

Journal of cardiovascular pharmacology, 1989-06, Vol.13 (6), p.887-894

1989

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Concentrations of angiotensin-converting enzyme in tissues of the rat

BBA - Enzymology, 1971-10, Vol.250 (1), p.261-265

1971

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Blood Pressure Lowering and Renal Hemodynamic Effects of Fosinopril in Conscious Animal Models

Journal of cardiovascular pharmacology, 1990-07, Vol.16 (1), p.139-146

1990

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Ketomethyldipeptides I. A new class of angiotensin converting enzyme inhibitors

Biochemical and biophysical research communications, 1984-10, Vol.124 (1), p.141-147

1984

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Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Science (American Association for the Advancement of Science), 1977-04, Vol.196 (4288), p.441-444

1977

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Ketomethyldipeptides II. Effect of modifications of the α-aminoketone portion on inhibition of angiotensin converting enzyme

Biochemical and biophysical research communications, 1984-10, Vol.124 (1), p.148-155

1984

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(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline, a novel orally active inhibitor of ACE

Journal of medicinal chemistry, 1988-01, Vol.31 (1), p.204-212

1988

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Design of protease inhibitors

Biopolymers, 1981-09, Vol.20 (9), p.2001-2010

1981

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Angiotensin-Converting Enzyme Inhibitors: Accomplishments and Challenges

Clinical and experimental hypertension (1993), 1987, Vol.A9 (2-3), p.235-241

1987

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A simplified method for purification of the creatine kinase isoenzyme of human brain (BB)

Clinica chimica acta, 1980-01, Vol.106 (3), p.339-345

1980

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Inhibition of the renin-angiotensin system. A new approach to the therapy of hypertension

Journal of medicinal chemistry, 1981-04, Vol.24 (4), p.355-361

1981

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Effect of substrate concentration on inhibition of prostaglandin synthetase of bull seminal vesicles by anti-inflammatory drugs and fenamic acid analogs

Biochimica et biophysica acta, 1976-03, Vol.424 (3), p.449-459

1976

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(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme. 2. Terminal amino acid analogs of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline

Journal of medicinal chemistry, 1990-05, Vol.33 (5), p.1459-1469

1990

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Design of angiotensin converting enzyme inhibitors

History of the Design of Captopril and Related Inhibitors of Angiotensin Converting Enzyme

Effects of different angiotensin-converting enzyme (ACE) inhibitors on ischemic isolated rat hearts: relationship between cardiac ACE inhibition and cardioprotection

Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE)

Enzymes of the Renin-Angiotensin System and their Inhibitors

Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

Differentiation of angiotensin-converting enzyme (ACE) inhibitors by their selective inhibition of ACE in physiologically important target organs

Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines

Design of novel inhibitors of aminopeptidases. Synthesis of peptide-derived diamino thiols and sulfur replacement analogs of bestatin

Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence

Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung

Fosinopril, a Phosphinic Acid Inhibitor of Angiotensin I Converting Enzyme: In Vitro and Preclinical In Vivo Pharmacology

Preclinical Pharmacology of Zofenopril, an Inhibitor of Angiotensin I Converting Enzyme

Concentrations of angiotensin-converting enzyme in tissues of the rat

Blood Pressure Lowering and Renal Hemodynamic Effects of Fosinopril in Conscious Animal Models

Ketomethyldipeptides I. A new class of angiotensin converting enzyme inhibitors

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Ketomethyldipeptides II. Effect of modifications of the α-aminoketone portion on inhibition of angiotensin converting enzyme

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline, a novel orally active inhibitor of ACE

Design of protease inhibitors

Angiotensin-Converting Enzyme Inhibitors: Accomplishments and Challenges

A simplified method for purification of the creatine kinase isoenzyme of human brain (BB)

Inhibition of the renin-angiotensin system. A new approach to the therapy of hypertension

Effect of substrate concentration on inhibition of prostaglandin synthetase of bull seminal vesicles by anti-inflammatory drugs and fenamic acid analogs

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme. 2. Terminal amino acid analogs of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline

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