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Evaluation and treatment of acetaminophen toxicity

Advances in pharmacology (1990), 2019, Vol.85, p.263-272

2019

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The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

The Journal of clinical investigation, 2012-04, Vol.122 (4), p.1574-1583

2012

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Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (33), p.12169-12174

2014

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COVID-19 Time of Intubation Mortality Evaluation (C-TIME): A system for predicting mortality of patients with COVID-19 pneumonia at the time they require mechanical ventilation

PloS one, 2022-07, Vol.17 (7), p.e0270193-e0270193

2022

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The relationship of tidal volume and driving pressure with mortality in hypoxic patients receiving mechanical ventilation

PloS one, 2021-08, Vol.16 (8), p.e0255812

2021

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The Evolution of Circulating Biomarkers for Use in Acetaminophen/Paracetamol-Induced Liver Injury in Humans: A Scoping Review

Livers, 2023-12, Vol.3 (4), p.569-596

2023

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Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients

Toxicological sciences, 2014-12, Vol.142 (2), p.436-444

2014

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Improving Clinical Interpretation of the Anti-Platelet Factor 4/Heparin Enzyme-Linked Immunosorbent Assay for the Diagnosis of Heparin-Induced Thrombocytopenia Through the Use of Receiver Operating Characteristic Analysis, Stratum-Specific Likelihood Ratios, and Bayes Theorem

Chest, 2013-10, Vol.144 (4), p.1269-1275

2013

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Discriminant Accuracy of the SOFA Score for Determining the Probable Mortality of Patients With COVID-19 Pneumonia Requiring Mechanical Ventilation

JAMA : the journal of the American Medical Association, 2021-04, Vol.325 (14), p.1469

2021

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The Computational Acid-Base Chemistry of Hepatic Ketoacidosis

Metabolites, 2023-06, Vol.13 (7), p.803

2023

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Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose

Archives of toxicology, 2022-02, Vol.96 (2), p.453-465

2022

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4-methylpyrazole protects against acetaminophen-induced acute kidney injury

Toxicology and applied pharmacology, 2020-12, Vol.409, p.115317-115317, Article 115317

2020

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Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure

Biochemical pharmacology, 2024-10, Vol.228, p.116056, Article 116056

2024

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Computerised risk scores to guide recognition and diagnosis in patients with possible heparin‐induced thrombocytopenia

British journal of haematology, 2021-01, Vol.192 (1), p.146-150

2021

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Clinical decision support to reduce unnecessary diagnostic testing for heparin-induced thrombocytopaenia

British journal of haematology, 2023-06

2023

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Clinical decision support to reduce unnecessary diagnostic testing for heparin‐induced thrombocytopenia

British journal of haematology, 2023-09, Vol.202 (5), p.1011-1017

2023

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A New F(ab’)2 Antivenom for the Treatment of Crotaline Envenomation in Children

The American journal of emergency medicine, 2016-10, Vol.34 (10), p.2003-2006

2016

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Identification of populations likely to benefit from pharmacogenomic testing

Pharmacogenetics and genomics, 2020-07, Vol.30 (5), p.91-95

2020

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The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure

Hepatology (Baltimore, Md.), 2024-06, Vol.79 (6), p.1352

2024

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Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients

Toxicology letters, 2022-08, Vol.367, p.59-66

2022

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Ethylene Glycol Elimination Kinetics and Outcomes in Patients Managed Without Hemodialysis

Annals of emergency medicine, 2012-06, Vol.59 (6), p.527-531

2012

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Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole

Archives of toxicology, 2021-10, Vol.95 (10), p.3377-3391

2021

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A Bayesian Analysis of Strategies to Rule Out Coronavirus Disease 2019 (COVID-19) Using Reverse Transcriptase–Polymerase Chain Reaction

Archives of pathology & laboratory medicine (1976), 2020-08, Vol.144 (8), p.915-916

2020

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Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans

Archives of toxicology, 2014-02, Vol.88 (2), p.391-401

2014

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Evaluation and treatment of acetaminophen toxicity

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis

COVID-19 Time of Intubation Mortality Evaluation (C-TIME): A system for predicting mortality of patients with COVID-19 pneumonia at the time they require mechanical ventilation

The relationship of tidal volume and driving pressure with mortality in hypoxic patients receiving mechanical ventilation

The Evolution of Circulating Biomarkers for Use in Acetaminophen/Paracetamol-Induced Liver Injury in Humans: A Scoping Review

Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients

Improving Clinical Interpretation of the Anti-Platelet Factor 4/Heparin Enzyme-Linked Immunosorbent Assay for the Diagnosis of Heparin-Induced Thrombocytopenia Through the Use of Receiver Operating Characteristic Analysis, Stratum-Specific Likelihood Ratios, and Bayes Theorem

Discriminant Accuracy of the SOFA Score for Determining the Probable Mortality of Patients With COVID-19 Pneumonia Requiring Mechanical Ventilation

The Computational Acid-Base Chemistry of Hepatic Ketoacidosis

Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose

4-methylpyrazole protects against acetaminophen-induced acute kidney injury

Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure

Computerised risk scores to guide recognition and diagnosis in patients with possible heparin‐induced thrombocytopenia

Clinical decision support to reduce unnecessary diagnostic testing for heparin-induced thrombocytopaenia

Clinical decision support to reduce unnecessary diagnostic testing for heparin‐induced thrombocytopenia

A New F(ab’)2 Antivenom for the Treatment of Crotaline Envenomation in Children

Identification of populations likely to benefit from pharmacogenomic testing

The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure

Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients

Ethylene Glycol Elimination Kinetics and Outcomes in Patients Managed Without Hemodialysis

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole

A Bayesian Analysis of Strategies to Rule Out Coronavirus Disease 2019 (COVID-19) Using Reverse Transcriptase–Polymerase Chain Reaction

Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans

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