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A Mild, One-Pot Stadler-Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous-Flow

Angewandte Chemie (International ed.), 2013-07, Vol.52 (30), p.7860-7864

International ed. in English, 2013

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8-, 9-, and 11-Aryloxy Dimeric Aporphines and Their Pharmacological Activities

Molecules (Basel, Switzerland), 2021-07, Vol.26 (15), p.4521

2021

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A new class of small molecule inhibitor of BMP signaling

PloS one, 2013-04, Vol.8 (4), p.e62721

2013

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Microwave assisted copper-free Sonogashira coupling/5-exo- dig cycloisomerization domino reaction: access to 3-(phenylmethylene)isoindolin-1-ones and related heterocycles

Tetrahedron letters, 2011-10, Vol.52 (42), p.5508-5511

2011

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Identification of RIP1 kinase as a specific cellular target of necrostatins

Nature chemical biology, 2008-05, Vol.4 (5), p.313-321

2008

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Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1

Cell reports (Cambridge), 2015-03, Vol.10 (11), p.1850-1860

2015

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Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

Cancer cell, 2010-10, Vol.18 (4), p.382-395

2010

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Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells

Molecular cancer therapeutics, 2013-12, Vol.12 (12), p.2651-2662

2013

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BMP type I receptor inhibition reduces heterotopic [corrected] ossification

Nature medicine, 2008-12, Vol.14 (12), p.1363-1369

2008

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Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease

PLoS biology, 2014-08, Vol.12 (8), p.e1001923-e1001923

2014

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Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease

The Journal of experimental medicine, 2015-03, Vol.212 (3), p.319-332

2015

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Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.7900-7915

2014

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Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection

The Journal of clinical investigation, 2014-03, Vol.124 (3), p.1255-1267

2014

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Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor

ACS chemical biology, 2013-06, Vol.8 (6), p.1291-1302

2013

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Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

Bioorganic & medicinal chemistry, 2008-08, Vol.18 (15), p.4388-4392

2008

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Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.4028-4043

2013

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A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011781-e1011781

2023

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Current status and challenges in drug discovery against the globally important zoonotic cryptosporidiosis

Animal diseases, 2021-04, Vol.1 (1), p.1-10, Article 3

2021

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RIPK protein kinase family: Atypical lives of typical kinases

Seminars in cell & developmental biology, 2021-01, Vol.109, p.96-105

2021

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Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis

PloS one, 2013-03, Vol.8 (3), p.e56576-e56576

2013

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Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold

European journal of medicinal chemistry, 2020-08, Vol.200, p.112417-112417, Article 112417

2020

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Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis

Antimicrobial Agents and Chemotherapy, 2014-03, Vol.58 (3), p.1603-1614

2014

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Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds

PloS one, 2015-10, Vol.10 (10), p.e0138976-e0138976

2015

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Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor

Cell death & disease, 2021-07, Vol.12 (7), p.699-699, Article 699

2021

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Synthesis of the Tetracyclic Framework of Polycyclic Spiro Lignan Natural Products

ACS omega, 2020-04, Vol.5 (15), p.9007-9012

2020

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A Mild, One-Pot Stadler-Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous-Flow

8-, 9-, and 11-Aryloxy Dimeric Aporphines and Their Pharmacological Activities

A new class of small molecule inhibitor of BMP signaling

Microwave assisted copper-free Sonogashira coupling/5-exo- dig cycloisomerization domino reaction: access to 3-(phenylmethylene)isoindolin-1-ones and related heterocycles

Identification of RIP1 kinase as a specific cellular target of necrostatins

Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells

BMP type I receptor inhibition reduces heterotopic [corrected] ossification

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease

Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection

Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor

Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex

Current status and challenges in drug discovery against the globally important zoonotic cryptosporidiosis

RIPK protein kinase family: Atypical lives of typical kinases

Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis

Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold

Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis

Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds

Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor

Synthesis of the Tetracyclic Framework of Polycyclic Spiro Lignan Natural Products

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