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Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6377), p.801-806

2018

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FLT3 Mutations Confer Enhanced Proliferation and Survival Properties to Multipotent Progenitors in a Murine Model of Chronic Myelomonocytic Leukemia

Cancer cell, 2007-10, Vol.12 (4), p.367-380

2007

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FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

Cell, 2007-01, Vol.128 (2), p.325-339

2007

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Zinc Finger Protein ZFP57 Requires Its Co-factor to Recruit DNA Methyltransferases and Maintains DNA Methylation Imprint in Embryonic Stem Cells via Its Transcriptional Repression Domain

The Journal of biological chemistry, 2012-01, Vol.287 (3), p.2107-2118

2012

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Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

Cancer cell, 2008-04, Vol.13 (4), p.311-320

2008

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Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.E2020-E2029

2015

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Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis

Cell stem cell, 2009-06, Vol.4 (6), p.559-567

2009

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Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress

Blood, 2012-05, Vol.119 (21), p.4898-4907

2012

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Open-label phase II/III study of nivolumab plus standard of care versus standard of care for first-line treatment of metastatic colorectal cancer: Checkmate-9X8

Journal of clinical oncology, 2019-02, Vol.37 (4_suppl), p.TPS718-TPS718

2019

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Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (14), p.6001-6006

2007

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Modified FOLFOX6 plus bevacizumab with and without nivolumab for first-line treatment of metastatic colorectal cancer: phase 2 results from the CheckMate 9X8 randomized clinical trial

Journal for immunotherapy of cancer, 2024-03, Vol.12 (3), p.e008409

2024

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Ott1 (Rbm15) Is Essential for Placental Vascular Branching Morphogenesis and Embryonic Development of the Heart and Spleen

Molecular and Cellular Biology, 2009-01, Vol.29 (2), p.333-341

2009

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'Half-Cut' Science: A Qualitative Examination of Alcohol Industry Actors' Use of Peer-Reviewed Evidence in Policy Submissions on Minimum Unit Pricing

Evidence & Policy: A Journal of Research, Debate and Practice, 2019-01, Vol.15 (1), p.49

2019

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Nivolumab (NIVO) + 5-fluorouracil/leucovorin/oxaliplatin (mFOLFOX6)/bevacizumab (BEV) versus mFOLFOX6/BEV for first-line (1L) treatment of metastatic colorectal cancer (mCRC): Phase 2 results from CheckMate 9X8

Journal of clinical oncology, 2022-02, Vol.40 (4_suppl), p.8-8

2022

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Abstract 3636: Potent antitumor activity of duvortuxizumab, a CD19 x CD3 DART® molecule, in lymphoma models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3636-3636

2017

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First-line (1L) nivolumab (NIVO) plus chemotherapy (chemo) versus chemo in advanced gastric cancer/gastroesophageal junction cancer/esophageal adenocarcinoma (GC/GEJC/EAC): Expanded efficacy and safety data from CheckMate 649

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.4002-4002

2021

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Loss-of-function of PBRM1 to predict response to anti-PD-1/PD-L1 therapy in metastatic renal cell carcinoma

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.3016-3016

2017

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The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

The Journal of clinical investigation, 2009-04, Vol.119 (4), p.852-864

2009

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JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

Blood, 2006-10, Vol.108 (8), p.2770-2779

2006

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The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRβ and FIP1L1-PDGFRα in vitro and in vivo

Blood, 2005-11, Vol.106 (9), p.3206-3213

2005

Volltextzugriff (PDF)

Maternal and zygoticZfp57modulate NOTCH signaling in cardiac development

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.E2020-E2029

2015

Volltextzugriff (PDF)

Oxidative Stress-Mediated Activation of AKT/mTOR Signaling Pathway Leads to Myeloproliferative Syndrome in FoxO3 Null Mice: A Role for Lnk Adaptor Protein

Blood, 2008-11, Vol.112 (11), p.509-509

2008

Volltextzugriff (PDF)

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Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

FLT3 Mutations Confer Enhanced Proliferation and Survival Properties to Multipotent Progenitors in a Murine Model of Chronic Myelomonocytic Leukemia

FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

Zinc Finger Protein ZFP57 Requires Its Co-factor to Recruit DNA Methyltransferases and Maintains DNA Methylation Imprint in Embryonic Stem Cells via Its Transcriptional Repression Domain

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development

Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis

Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress

Open-label phase II/III study of nivolumab plus standard of care versus standard of care for first-line treatment of metastatic colorectal cancer: Checkmate-9X8

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Modified FOLFOX6 plus bevacizumab with and without nivolumab for first-line treatment of metastatic colorectal cancer: phase 2 results from the CheckMate 9X8 randomized clinical trial

Ott1 (Rbm15) Is Essential for Placental Vascular Branching Morphogenesis and Embryonic Development of the Heart and Spleen

First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial

'Half-Cut' Science: A Qualitative Examination of Alcohol Industry Actors' Use of Peer-Reviewed Evidence in Policy Submissions on Minimum Unit Pricing

Nivolumab (NIVO) + 5-fluorouracil/leucovorin/oxaliplatin (mFOLFOX6)/bevacizumab (BEV) versus mFOLFOX6/BEV for first-line (1L) treatment of metastatic colorectal cancer (mCRC): Phase 2 results from CheckMate 9X8

Nivolumab plus chemotherapy versus chemotherapy as first-line treatment for advanced gastric cancer/gastroesophageal junction cancer/oesophageal adenocarcinoma (CheckMate 649): a multicentre, randomised, open-label, phase 3 trial

Abstract 3636: Potent antitumor activity of duvortuxizumab, a CD19 x CD3 DART® molecule, in lymphoma models

First-line (1L) nivolumab (NIVO) plus chemotherapy (chemo) versus chemo in advanced gastric cancer/gastroesophageal junction cancer/esophageal adenocarcinoma (GC/GEJC/EAC): Expanded efficacy and safety data from CheckMate 649

A plain language summary of the CheckMate 649 study: nivolumab in combination with chemotherapy compared to chemotherapy alone for untreated advanced or metastatic cancer of the stomach or esophagus

Loss-of-function of PBRM1 to predict response to anti-PD-1/PD-L1 therapy in metastatic renal cell carcinoma

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRβ and FIP1L1-PDGFRα in vitro and in vivo

Maternal and zygoticZfp57modulate NOTCH signaling in cardiac development

Oxidative Stress-Mediated Activation of AKT/mTOR Signaling Pathway Leads to Myeloproliferative Syndrome in FoxO3 Null Mice: A Role for Lnk Adaptor Protein

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