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evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (28), p.11676-11681

2007

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The Diversity of Dolichol-Linked Precursors to Asn-Linked Glycans Likely Results from Secondary Loss of Sets of Glycosyltransferases

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (5), p.1548-1553

2005

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Giardia, Entamoeba, and Trichomonas Enzymes Activate Metronidazole (Nitroreductases) and Inactivate Metronidazole (Nitroimidazole Reductases)

Antimicrobial Agents and Chemotherapy, 2009-02, Vol.53 (2), p.458-464

2009

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Roundup 2.0: enabling comparative genomics for over 1800 genomes

Bioinformatics (Oxford, England), 2012-03, Vol.28 (5), p.715-716

2012

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Darwinian Selection for Sites of Asn-Linked Glycosylation in Phylogenetically Disparate Eukaryotes and Viruses

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (32), p.13421-13426

2009

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Suggestive Evidence for Darwinian Selection against Asparagine-Linked Glycans of Plasmodium falciparum and Toxoplasma gondii

Eukaryotic Cell, 2010-02, Vol.9 (2), p.228-241

2010

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Changes in the N-Glycome, Glycoproteins with Asn-Linked Glycans, of Giardia lamblia with Differentiation from Trophozoites to Cysts

Eukaryotic Cell, 2008-11, Vol.7 (11), p.1930-1940

2008

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Analysis of bacterial communities on aging flue-cured tobacco leaves by 16S rDNA PCR-DGGE technology

Applied microbiology and biotechnology, 2007, Vol.73 (6), p.1435-1440

2007

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Detecting biological network organization and functional gene orthologs

Bioinformatics, 2011-10, Vol.27 (20), p.2919-2920

2011

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Trichomonas transmembrane cyclases result from massive gene duplication and concomitant development of pseudogenes

PLoS neglected tropical diseases, 2010-08, Vol.4 (8), p.e782

2010

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Phylogenetically informed logic relationships improve detection of biological network organization

BMC bioinformatics, 2011-12, Vol.12 (1), p.476-476, Article 476

2011

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Unique Asn-linked Oligosaccharides of the Human Pathogen Entamoeba histolytica

The Journal of biological chemistry, 2008-06, Vol.283 (26), p.18355-18364

2008

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The cyst wall of Entamoeba invadens contains chitosan (deacetylated chitin)

Molecular and biochemical parasitology, 2006-07, Vol.148 (1), p.86-92

2006

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A community effort to assess and improve drug sensitivity prediction algorithms

Nature biotechnology, 2014-12, Vol.32 (12), p.1202-1212

2014

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The Antiretroviral Lectin Cyanovirin-N Targets Well-Known and Novel Targets on the Surface of Entamoeba histolytica Trophozoites

Eukaryotic Cell, 2010-11, Vol.9 (11), p.1661-1668

2010

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MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis

Journal of clinical oncology, 2023-11, Vol.41 (32), p.4993-5004

2023

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Clinical Benefit Associated with Biomarker Changes Indicative of Disease Modification in Patients with Myelofibrosis Treated with the BET Inhibitor Pelabresib As Monotherapy or in Combination with Ruxolitinib

Blood, 2022-11, Vol.140 (Supplement 1), p.1523-1525

2022

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Dolichyl-Phosphate-Glucose Is Used To Make O-Glycans on Glycoproteins of Trichomonas vaginalis

Eukaryotic Cell, 2008-08, Vol.7 (8), p.1344-1351

2008

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Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers

Cancer research (Chicago, Ill.), 2024-08, Vol.84 (15), p.2501-2517

2024

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MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22 Suppl 2, p.S331-S332

2022

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Poster: MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S156

2022

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Pelabresib (CPI-0610) Monotherapy in Patients with Myelofibrosis - Update of Clinical and Translational Data from the Ongoing Manifest Trial

Blood, 2021-11, Vol.138 (Supplement 1), p.141-141

2021

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Phase 1/2 first-in-human (FIH) study of CPI-0209, a novel small molecule inhibitor of enhancer of zeste homolog 2 (EZH2) in patients with advanced tumors

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.3104-3104

2021

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Pelabresib Plus Ruxolitinib Combination Therapy in JAK Inhibitor-Naïve Patients With Myelofibrosis in the Phase 3 MANIFEST-2 Study: Preliminary Evidence of Bone Marrow Recovery

Clinical lymphoma, myeloma and leukemia, 2024-09, Vol.24, p.S200-S200

2024

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evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation

The Diversity of Dolichol-Linked Precursors to Asn-Linked Glycans Likely Results from Secondary Loss of Sets of Glycosyltransferases

Giardia, Entamoeba, and Trichomonas Enzymes Activate Metronidazole (Nitroreductases) and Inactivate Metronidazole (Nitroimidazole Reductases)

Roundup 2.0: enabling comparative genomics for over 1800 genomes

Darwinian Selection for Sites of Asn-Linked Glycosylation in Phylogenetically Disparate Eukaryotes and Viruses

Suggestive Evidence for Darwinian Selection against Asparagine-Linked Glycans of Plasmodium falciparum and Toxoplasma gondii

Changes in the N-Glycome, Glycoproteins with Asn-Linked Glycans, of Giardia lamblia with Differentiation from Trophozoites to Cysts

Analysis of bacterial communities on aging flue-cured tobacco leaves by 16S rDNA PCR-DGGE technology

Detecting biological network organization and functional gene orthologs

Trichomonas transmembrane cyclases result from massive gene duplication and concomitant development of pseudogenes

Phylogenetically informed logic relationships improve detection of biological network organization

Unique Asn-linked Oligosaccharides of the Human Pathogen Entamoeba histolytica

The cyst wall of Entamoeba invadens contains chitosan (deacetylated chitin)

A community effort to assess and improve drug sensitivity prediction algorithms

The Antiretroviral Lectin Cyanovirin-N Targets Well-Known and Novel Targets on the Surface of Entamoeba histolytica Trophozoites

MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis

Clinical Benefit Associated with Biomarker Changes Indicative of Disease Modification in Patients with Myelofibrosis Treated with the BET Inhibitor Pelabresib As Monotherapy or in Combination with Ruxolitinib

Dolichyl-Phosphate-Glucose Is Used To Make O-Glycans on Glycoproteins of Trichomonas vaginalis

Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers

MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood

Poster: MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood

Pelabresib (CPI-0610) Monotherapy in Patients with Myelofibrosis - Update of Clinical and Translational Data from the Ongoing Manifest Trial

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) As Demonstrated By Improvements in Bone Marrow Function and Clinical Activity in Patients with Myelofibrosis - Preliminary Data

Phase 1/2 first-in-human (FIH) study of CPI-0209, a novel small molecule inhibitor of enhancer of zeste homolog 2 (EZH2) in patients with advanced tumors

Pelabresib Plus Ruxolitinib Combination Therapy in JAK Inhibitor-Naïve Patients With Myelofibrosis in the Phase 3 MANIFEST-2 Study: Preliminary Evidence of Bone Marrow Recovery

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