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Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists

Nature communications, 2021-07, Vol.12 (1), p.4351-4351, Article 4351

2021

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NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia

Behavioural brain research, 2023-10, Vol.454, p.114614-114614, Article 114614

2023

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Saccharin Derivatives as Inhibitors of Interferon-Mediated Inflammation

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5348-5355

2014

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Facile synthesis of 6,12b-diaza-dibenzo[a,h]azulen-7-ones and benzo[f]pyrrolo[1,2-a][1,4]diazepin-4-ones via CuI/l-proline catalyzed intramolecular N-arylation

Tetrahedron letters, 2011-01, Vol.52 (4), p.541-543

2011

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Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation

ChemMedChem, 2016-01, Vol.11 (2), p.154-165

2016

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Multifunctional Building Blocks Compatible with Photoredox-Mediated Alkylation for DNA-Encoded Library Synthesis

Organic letters, 2020-02, Vol.22 (3), p.1046-1051

2020

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2-Trifluoroacetyl aminoindoles as useful intermediates for the preparation of 2-acylamino indoles

Tetrahedron letters, 2011-03, Vol.52 (12), p.1292-1295

2011

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Photoredox-catalysed hydroaminoalkylation of on-DNA -arylamines

Organic & biomolecular chemistry, 2023-02, Vol.21 (7), p.1463-1467

2023

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Photoredox-mediated hydroalkylation and hydroarylation of functionalized olefins for DNA-encoded library synthesis

Chemical science (Cambridge), 2021-09, Vol.12 (36), p.1236-1245

2021

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On-DNA hydroalkylation of -vinyl heterocycles photoinduced EDA-complex activation

Chemical science (Cambridge), 2023-12, Vol.14 (48), p.14193-14199

2023

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Photochemical C-H arylation of heteroarenes for DNA-encoded library synthesis

Chemical science (Cambridge), 2022-01, Vol.13 (4), p.123-129

2022

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On-DNA hydroalkylation of N -vinyl heterocycles via photoinduced EDA-complex activation

Chemical science (Cambridge), 2023-12, Vol.14 (48), p.14193-14199

2023

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Photoredox-catalysed hydroaminoalkylation of on-DNA N -arylamines

Organic & biomolecular chemistry, 2023-02, Vol.21 (7), p.1463-1467

2023

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Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library

Journal of medicinal chemistry, 2024-02, Vol.67 (3), p.2049-2065

2024

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NU-1223, a simplified analog of alstonine, with 5-HT 2c R agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia

Behavioural brain research, 2023-08, p.114614

2023

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Discovery of Highly Potent Serotonin 5‑HT2 Receptor Agonists Inspired by Heteroyohimbine Natural Products

ACS medicinal chemistry letters, 2022-04, Vol.13 (4), p.648-657

2022

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Discovery of Highly Potent Serotonin 5-HT 2 Receptor Agonists Inspired by Heteroyohimbine Natural Products

ACS medicinal chemistry letters, 2022-04, Vol.13 (4), p.648-657

2022

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Targeting the lateral interactions of transmembrane domain 5 of Epstein–Barr virus latent membrane protein 1

Biochimica et biophysica acta, 2012-09, Vol.1818 (9), p.2282-2289

2012

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Facile synthesis of 6,12 b-diaza-dibenzo[ a, h]azulen-7-ones and benzo[ f]pyrrolo[1,2- a][1,4]diazepin-4-ones via CuI/ l-proline catalyzed intramolecular N-arylation

Tetrahedron letters, 2011, Vol.52 (4), p.541-543

2011

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Design and Synthesis of Immune Signaling Modulators

Csakai, Adam Joseph

2017

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Efficient N-Arylation/Dealkylation of Electron Deficient Heteroaryl Chlorides and Bicyclic Tertiary Amines under Microwave Irradiation

Journal of combinatorial chemistry, 2009-05, Vol.11 (3), p.355-363

2009

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ChemInform Abstract: Facile Synthesis of 6,12b-Diaza-dibenzo[a,h]azulen-7-ones and Benzo[f]pyrrolo[1,2-a][1,4]diazepin-4-ones via CuI/L-Proline Catalyzed Intramolecular N-Arylation

ChemInform, 2011-05, Vol.42 (18), p.no-no

2011

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ChemInform Abstract: Efficient N-Arylation/Dealkylation of Electron Deficient Heteroaryl Chlorides and Bicyclic Tertiary Amines under Microwave Irradiation

ChemInform, 2009-09, Vol.40 (39), p.no-no

2009

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Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists

NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia

Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension

Saccharin Derivatives as Inhibitors of Interferon-Mediated Inflammation

Facile synthesis of 6,12b-diaza-dibenzo[a,h]azulen-7-ones and benzo[f]pyrrolo[1,2-a][1,4]diazepin-4-ones via CuI/l-proline catalyzed intramolecular N-arylation

Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation

Multifunctional Building Blocks Compatible with Photoredox-Mediated Alkylation for DNA-Encoded Library Synthesis

2-Trifluoroacetyl aminoindoles as useful intermediates for the preparation of 2-acylamino indoles

Photoredox-catalysed hydroaminoalkylation of on-DNA -arylamines

Photoredox-mediated hydroalkylation and hydroarylation of functionalized olefins for DNA-encoded library synthesis

On-DNA hydroalkylation of -vinyl heterocycles photoinduced EDA-complex activation

Photochemical C-H arylation of heteroarenes for DNA-encoded library synthesis

On-DNA hydroalkylation of N -vinyl heterocycles via photoinduced EDA-complex activation

Photoredox-catalysed hydroaminoalkylation of on-DNA N -arylamines

Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library

NU-1223, a simplified analog of alstonine, with 5-HT 2c R agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia

Discovery of Highly Potent Serotonin 5‑HT2 Receptor Agonists Inspired by Heteroyohimbine Natural Products

Discovery of Highly Potent Serotonin 5-HT 2 Receptor Agonists Inspired by Heteroyohimbine Natural Products

Targeting the lateral interactions of transmembrane domain 5 of Epstein–Barr virus latent membrane protein 1

Facile synthesis of 6,12 b-diaza-dibenzo[ a, h]azulen-7-ones and benzo[ f]pyrrolo[1,2- a][1,4]diazepin-4-ones via CuI/ l-proline catalyzed intramolecular N-arylation

Design and Synthesis of Immune Signaling Modulators

Efficient N-Arylation/Dealkylation of Electron Deficient Heteroaryl Chlorides and Bicyclic Tertiary Amines under Microwave Irradiation

ChemInform Abstract: Facile Synthesis of 6,12b-Diaza-dibenzo[a,h]azulen-7-ones and Benzo[f]pyrrolo[1,2-a][1,4]diazepin-4-ones via CuI/L-Proline Catalyzed Intramolecular N-Arylation

ChemInform Abstract: Efficient N-Arylation/Dealkylation of Electron Deficient Heteroaryl Chlorides and Bicyclic Tertiary Amines under Microwave Irradiation

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