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Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance

Toxicological sciences, 2017-10, Vol.159 (2), p.413-421

2017

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Assessment of the cancer potential of methanol

Critical reviews in toxicology, 2009-04, Vol.39 (4), p.347-363

Cruzan, George

2009

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Methyl tertiary-butyl ether mode of action for cancer endpoints in rodents

Regulatory toxicology and pharmacology, 2007-03, Vol.47 (2), p.156-165

2007

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Chronic toxicity/oncogenicity study of styrene in cd-1 mice by inhalation exposure for 104 weeks

Journal of applied toxicology, 2001-05, Vol.21 (3), p.185-198

2001

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Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: An endpoint/toxic response where data from multiple chemicals converge to support a mode of action

Regulatory toxicology and pharmacology, 2009-11, Vol.55 (2), p.205-218

2009

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Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern

Regulatory toxicology and pharmacology, 2018-06, Vol.95, p.17-28

2018

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Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures

Toxicology and applied pharmacology, 2017-11, Vol.335, p.28-40

2017

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Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment

Regulatory toxicology and pharmacology, 2018-07, Vol.96, p.153-166

2018

Volltextzugriff (PDF)

Evaluation of the mode of action of mouse lung tumors induced by 4-methylimidazole

Regulatory toxicology and pharmacology, 2015-11, Vol.73 (2), p.501-508

2015

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Subchronic Toxicity of Ethylene Glycol in Wistar and F-344 Rats Related to Metabolism and Clearance of Metabolites

Toxicological sciences, 2004-10, Vol.81 (2), p.502-511

2004

Volltextzugriff (PDF)

Tertiary-Butyl Acetate Metabolism, Toxicity, and Human Health Considerations

Toxicological and environmental chemistry, 2006-01, Vol.88 (1), p.405-405

2006

Volltextzugriff (PDF)

PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING OF STYRENE AND STYRENE OXIDE RESPIRATORY-TRACT DOSIMETRY IN RODENTS AND HUMANS

Inhalation toxicology, 2002-08, Vol.14 (8), p.789-834

2002

Volltextzugriff (PDF)

In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol

Xenobiotica, 2011-01, Vol.41 (1), p.6-23

2011

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Ring-Oxidized Metabolites of Styrene Contribute to Styrene-Induced Clara-Cell Toxicity in Mice

Journal of Toxicology and Environmental Health, Part A, 2005-02, Vol.68 (3), p.229-237

2005

Volltextzugriff (PDF)

Tertiary-butyl acetate metabolism, toxicity, and human health considerations

Toxicological and environmental chemistry, 2006-07, Vol.88 (3), p.405-421

2006

Volltextzugriff (PDF)

Styrene Respiratory Tract Toxicity and Mouse Lung Tumors Are Mediated by CYP2F-Generated Metabolites

Regulatory toxicology and pharmacology, 2002-06, Vol.35 (3), p.308-319

2002

Volltextzugriff (PDF)

Styrene and breast cancer incidence in Texas: a comment on an ecological association

Breast cancer research and treatment, 2006-06, Vol.97 (3), p.339-340

2006

Volltextzugriff (PDF)

Chronic Toxicity/Oncogenicity Study of Styrene in CD Rats by Inhalation Exposure for 104 Weeks

Toxicological sciences, 1998-12, Vol.46 (2), p.266-281

1998

Volltextzugriff (PDF)

Developmental neurotoxicity study of styrene by inhalation in Crl-CD rats

Birth defects research. Part B. Developmental and reproductive toxicology, 2005-06, Vol.74 (3), p.221-232

2005

Volltextzugriff (PDF)

COMPARING RESPIRATORY-TRACT AND HEPATIC EXPOSURE-DOSE RELATIONSHIPS FOR METABOLIZED INHALED VAPORS: A PHARMACOKINETIC ANALYSIS

Inhalation toxicology, 2002-08, Vol.14 (8), p.835-854

2002

Volltextzugriff (PDF)

Two generation reproduction study of styrene by inhalation in Crl-CD rats

Birth defects research. Part B. Developmental and reproductive toxicology, 2005-06, Vol.74 (3), p.211-220

2005

Volltextzugriff (PDF)

A Comprehensive Evaluation of the Mechanism of Skin Tumorigenesis by Straight-Run and Cracked Petroleum Middle Distillates

Toxicological sciences, 1998-07, Vol.44 (1), p.22-31

1998

Volltextzugriff (PDF)

Determination of styrene in selected foods

Journal of agricultural and food chemistry, 1994-08, Vol.42 (8), p.1661-1665

1994

Volltextzugriff (PDF)

A Composite Model for Multiple Assays of Skin Irritation

Toxicology and industrial health, 1986-09, Vol.2 (3), p.309-320

1986

Volltextzugriff (PDF)

A Comprehensive Evaluation of the Mechanism of Skin Tumorigenesis by Straight-Run and Cracked Petroleum Middle Distillates

Toxicological sciences, 1998-07, Vol.44 (1), p.22-31

1998

Volltextzugriff (PDF)

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Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance

Assessment of the cancer potential of methanol

Methyl tertiary-butyl ether mode of action for cancer endpoints in rodents

Chronic toxicity/oncogenicity study of styrene in cd-1 mice by inhalation exposure for 104 weeks

Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: An endpoint/toxic response where data from multiple chemicals converge to support a mode of action

Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern

Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures

Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment

Evaluation of the mode of action of mouse lung tumors induced by 4-methylimidazole

Subchronic Toxicity of Ethylene Glycol in Wistar and F-344 Rats Related to Metabolism and Clearance of Metabolites

Tertiary-Butyl Acetate Metabolism, Toxicity, and Human Health Considerations

PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING OF STYRENE AND STYRENE OXIDE RESPIRATORY-TRACT DOSIMETRY IN RODENTS AND HUMANS

In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol

Ring-Oxidized Metabolites of Styrene Contribute to Styrene-Induced Clara-Cell Toxicity in Mice

Tertiary-butyl acetate metabolism, toxicity, and human health considerations

Styrene Respiratory Tract Toxicity and Mouse Lung Tumors Are Mediated by CYP2F-Generated Metabolites

Styrene and breast cancer incidence in Texas: a comment on an ecological association

Chronic Toxicity/Oncogenicity Study of Styrene in CD Rats by Inhalation Exposure for 104 Weeks

Developmental neurotoxicity study of styrene by inhalation in Crl-CD rats

COMPARING RESPIRATORY-TRACT AND HEPATIC EXPOSURE-DOSE RELATIONSHIPS FOR METABOLIZED INHALED VAPORS: A PHARMACOKINETIC ANALYSIS

Two generation reproduction study of styrene by inhalation in Crl-CD rats

A Comprehensive Evaluation of the Mechanism of Skin Tumorigenesis by Straight-Run and Cracked Petroleum Middle Distillates

Determination of styrene in selected foods

A Composite Model for Multiple Assays of Skin Irritation

A Comprehensive Evaluation of the Mechanism of Skin Tumorigenesis by Straight-Run and Cracked Petroleum Middle Distillates

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