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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines

Nature immunology, 2022-04, Vol.23 (4), p.532

2022

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Intratumoral Heterogeneity: From Diversity Comes Resistance

Clinical cancer research, 2015-07, Vol.21 (13), p.2916-2923

2015

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Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer

Cancer research (Chicago, Ill.), 2017-10, Vol.77 (20), p.5564-5575

2017

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Mutation position is an important determinant for predicting cancer neoantigens

The Journal of experimental medicine, 2020-04, Vol.217 (4)

2020

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Role of Histone H3 Lysine 27 Methylation in X Inactivation

Science (American Association for the Advancement of Science), 2003-04, Vol.300 (5616), p.131-135

2003

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NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma

eLife, 2019-05, Vol.8

2019

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A Rare Population of CD24+ITGB4+Notchhi Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal

Cancer cell, 2013-07, Vol.24 (1), p.59-74

2013

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Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein

Neuro-oncology (Charlottesville, Va.), 2020-06, Vol.22 (6), p.819-829

2020

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Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State

Cell metabolism, 2018-09, Vol.28 (3), p.383-399.e9

2018

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The Site-Specific Installation of Methyl-Lysine Analogs into Recombinant Histones

Cell, 2007-03, Vol.128 (5), p.1003-1012

2007

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Transcriptional Subtypes Resolve Tumor Heterogeneity and Identify Vulnerabilities to MEK Inhibition in Lung Adenocarcinoma

Clinical cancer research, 2021-02, Vol.27 (4), p.1162-1173

2021

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A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal

Cancer cell, 2013-07, Vol.24 (1), p.59-74

2013

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Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry

Analytical chemistry (Washington), 2023-03, Vol.95 (11), p.4834-4839

2023

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Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer

Science translational medicine, 2013-02, Vol.5 (171), p.171ra18

2013

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Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity

PloS one, 2012-10, Vol.7 (10), p.e45647-e45647

2012

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Polycomb Group Protein SUZ12 regulates histone H3 lysine 9 methylation and HP1α distribution

Chromosome research, 2007-04, Vol.15 (3), p.299-314

2007

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Developmental regulation of Suz12 localization

Chromosoma, 2005-08, Vol.114 (3), p.183-192

2005

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Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry

Analytical chemistry (Washington), 2023-03, Vol.95 (11), p.4834

2023

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Abstract P3-11-23: GDC-0077 is a selective PI3K alpha inhibitor with robust efficacy in PIK3CA mutant hormone-positive breast cancer models

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P3-P3-11-23

2020

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Abstract PO-101: Transcriptional heterogeneity in lung adenocarcinoma reveals distinct therapeutic vulnerabilities

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (21_Supplement), p.PO-101-PO-101

2020

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Abstract 3894: Determination of the efficacious Entrectinib exposures required for pathway inhibition and anti-tumor activity in a subcutaneous and intracranial TPM3-NTRK1 mutant tumor model

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3894-3894

2019

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Abstract 156: Preclinical characterization of GDC-0077, a specific PI3K alpha inhibitor in early clinical development

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.156-156

2017

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Abstract 266: Notch3 is a marker of tumor-propagating cells in non-small cell lung cancer and is required for their self-renewal

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.266-266

2013

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Abstract ED02-02: Notch defines the tumor initiating cell in non-small cell lung cancer

Cancer prevention research (Philadelphia, Pa.), 2012-11, Vol.5 (11_Supplement), p.ED02-02-ED02-02

2012

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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines

Intratumoral Heterogeneity: From Diversity Comes Resistance

Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer

Mutation position is an important determinant for predicting cancer neoantigens

Role of Histone H3 Lysine 27 Methylation in X Inactivation

NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma

A Rare Population of CD24+ITGB4+Notchhi Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal

Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein

Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State

The Site-Specific Installation of Methyl-Lysine Analogs into Recombinant Histones

Transcriptional Subtypes Resolve Tumor Heterogeneity and Identify Vulnerabilities to MEK Inhibition in Lung Adenocarcinoma

A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal

Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry

Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer

Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response

Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity

Polycomb Group Protein SUZ12 regulates histone H3 lysine 9 methylation and HP1α distribution

Developmental regulation of Suz12 localization

Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry

Abstract P3-11-23: GDC-0077 is a selective PI3K alpha inhibitor with robust efficacy in PIK3CA mutant hormone-positive breast cancer models

Abstract PO-101: Transcriptional heterogeneity in lung adenocarcinoma reveals distinct therapeutic vulnerabilities

Abstract 3894: Determination of the efficacious Entrectinib exposures required for pathway inhibition and anti-tumor activity in a subcutaneous and intracranial TPM3-NTRK1 mutant tumor model

Abstract 156: Preclinical characterization of GDC-0077, a specific PI3K alpha inhibitor in early clinical development

Abstract 266: Notch3 is a marker of tumor-propagating cells in non-small cell lung cancer and is required for their self-renewal

Abstract ED02-02: Notch defines the tumor initiating cell in non-small cell lung cancer

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