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Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)

Critical care medicine, 2019-05, Vol.47 (5), p.632-642

2019

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Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Intensive care medicine, 2019-10, Vol.45 (10), p.1360-1371

2019

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Mathematical model of sarcoidosis

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.16065-16070

2014

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Mitochondria in lung biology and pathology: more than just a powerhouse

American journal of physiology. Lung cellular and molecular physiology, 2014-06, Vol.306 (11), p.L962-L974

2014

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Current Sarcoidosis Models and the Importance of Focusing on the Granuloma

Frontiers in immunology, 2020-08, Vol.11, p.1719

2020

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Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA

Journal of intensive care, 2020-05, Vol.8 (1), p.33-33, Article 33

2020

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Challenges of Sarcoidosis and Its Management

The New England journal of medicine, 2021-09, Vol.385 (11), p.1018-1032

2021

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Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia

PloS one, 2021-01, Vol.16 (1), p.e0246083

2021

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Phase II Investigation of the Efficacy of Antimycobacterial Therapy in Chronic Pulmonary Sarcoidosis

Chest, 2021-05, Vol.159 (5), p.1902-1912

2021

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Mitochondrial transcription factor A, an endogenous danger signal, promotes TNFα release via RAGE- and TLR9-responsive plasmacytoid dendritic cells

PloS one, 2013-08, Vol.8 (8), p.e72354-e72354

2013

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Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA

The Journal of immunology (1950), 2012-07, Vol.189 (1), p.433-443

2012

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SCARLET (Supplemental Citicoline Administration to Reduce Lung injury Efficacy Trial): study protocol for a single-site, double-blinded, placebo-controlled, and randomized Phase 1/2 trial of i.v. citicoline (CDP-choline) in hospitalized SARS CoV-2-infected patients with hypoxemic acute respiratory failure

Trials, 2024-05, Vol.25 (1), p.328-19, Article 328

2024

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Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas

Respiratory research, 2020-12, Vol.21 (1), p.321-12, Article 321

2020

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Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes

PloS one, 2015-07, Vol.10 (7), p.e0132921-e0132921

2015

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Leveraging in vitro and pharmacokinetic models to support bench to bedside investigation of XTMAB-16 as a novel pulmonary sarcoidosis treatment

Frontiers in pharmacology, 2023-03, Vol.14, p.1066454-1066454

2023

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Role of imbalance between Th17 and regulatory T-cells in sarcoidosis

Current opinion in pulmonary medicine, 2018-09, Vol.24 (5), p.521-526

Crouser, Elliott D

2018

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Gene Expression Profiling Identifies MMP-12 and ADAMDEC1 as Potential Pathogenic Mediators of Pulmonary Sarcoidosis

American journal of respiratory and critical care medicine, 2009-05, Vol.179 (10), p.929-938

2009

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Resolution of abnormal cardiac MRI T2 signal following immune suppression for cardiac sarcoidosis

Journal of investigative medicine, 2016-08, Vol.64 (6), p.1148-1150

2016

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Application of laboratory models for sarcoidosis research

Journal of autoimmunity, 2024-03, p.103184-103184, Article 103184

2024

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Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors

Critical care medicine, 2009-06, Vol.37 (6), p.2000-2009

2009

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Lessons Learned from the ABCs of Granuloma Formation

American journal of respiratory cell and molecular biology, 2019-09, Vol.61 (3), p.277-278

Crouser, Elliott D

2019

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Nicotine Treatment Improves Toll-Like Receptor 2 and Toll-Like Receptor 9 Responsiveness in Active Pulmonary Sarcoidosis

Chest, 2013-02, Vol.143 (2), p.461-470

2013

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The landscape of transcriptomic and proteomic studies in sarcoidosis

ERJ open research, 2022, Vol.8 (1), p.621

2022

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Sepsis-Induced Renal Failure: Ischemia or Toxemia?

Critical care medicine, 2018-04, Vol.46 (4), p.658-660

Crouser, Elliott D

2018

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Carbamoyl phosphate synthase-1: A marker of mitochondrial damage and depletion in the liver during sepsis

Critical care medicine, 2006-09, Vol.34 (9), p.2439-2446

2006

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Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)

Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Mathematical model of sarcoidosis

Mitochondria in lung biology and pathology: more than just a powerhouse

Current Sarcoidosis Models and the Importance of Focusing on the Granuloma

Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA

Challenges of Sarcoidosis and Its Management

Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia

Phase II Investigation of the Efficacy of Antimycobacterial Therapy in Chronic Pulmonary Sarcoidosis

Mitochondrial transcription factor A, an endogenous danger signal, promotes TNFα release via RAGE- and TLR9-responsive plasmacytoid dendritic cells

Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA

Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas

Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes

Leveraging in vitro and pharmacokinetic models to support bench to bedside investigation of XTMAB-16 as a novel pulmonary sarcoidosis treatment

Role of imbalance between Th17 and regulatory T-cells in sarcoidosis

Gene Expression Profiling Identifies MMP-12 and ADAMDEC1 as Potential Pathogenic Mediators of Pulmonary Sarcoidosis

Resolution of abnormal cardiac MRI T2 signal following immune suppression for cardiac sarcoidosis

Application of laboratory models for sarcoidosis research

Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors

Lessons Learned from the ABCs of Granuloma Formation

Nicotine Treatment Improves Toll-Like Receptor 2 and Toll-Like Receptor 9 Responsiveness in Active Pulmonary Sarcoidosis

The landscape of transcriptomic and proteomic studies in sarcoidosis

Sepsis-Induced Renal Failure: Ischemia or Toxemia?

Carbamoyl phosphate synthase-1: A marker of mitochondrial damage and depletion in the liver during sepsis

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