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Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

Nature neuroscience, 2018-08, Vol.21 (8), p.1117

2018

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Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods

BMC genomics, 2019-06, Vol.20 (1), p.513-513, Article 513

2019

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Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19)

Molecular psychiatry, 2020-04, Vol.25 (4), p.831-843

2020

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Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

Cell reports (Cambridge), 2020-05, Vol.31 (5), p.107599-107599, Article 107599

2020

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Metabotropic Glutamate Receptors 2 and 3 as Targets for Treating Nicotine Addiction

Biological psychiatry (1969), 2018-06, Vol.83 (11), p.947-954

2018

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From bench to bedside: mGluR2 positive allosteric modulators as medications to treat substance use disorders

Psychopharmacology, 2017-05, Vol.234 (9-10), p.1347-1355

2017

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The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats

Neuropsychopharmacology (New York, N.Y.), 2016-11, Vol.41 (12), p.2932-2940

2016

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Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia

Molecular psychiatry, 2022-02, Vol.27 (2), p.1226-1232

2022

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The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys

Biological psychiatry (1969), 2015-10, Vol.78 (7), p.452-462

2015

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BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders

Neuron (Cambridge, Mass.), 2015-12, Vol.88 (6), p.1078-1083

2015

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Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators

Molecular pharmacology, 2018-05, Vol.93 (5), p.526-540

2018

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Derisking Psychiatric Drug Development: The NIMH's Fast Fail Program, A Novel Precompetitive Model

Journal of clinical psychopharmacology, 2016-10, Vol.36 (5), p.419-421

2016

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The central nervous system effects of the partial GABA‐Aα2,3‐selective receptor modulator AZD7325 in comparison with lorazepam in healthy males

British journal of clinical pharmacology, 2014-12, Vol.78 (6), p.1298-1314

2014

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Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening

Bioorganic & medicinal chemistry letters, 2018-10, Vol.28 (19), p.3231-3235

2018

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Alzheimer's disease research and development: a call for a new research roadmap

Annals of the New York Academy of Sciences, 2014-04, Vol.1313 (1), p.1-16

2014

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AZD6280, a novel partial γ-aminobutyric acid A receptor modulator, demonstrates a pharmacodynamically selective effect profile in healthy male volunteers

Journal of clinical psychopharmacology, 2015-02, Vol.35 (1), p.22-33

2015

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Differential Pharmacology and Binding of mGlu 2 Receptor Allosteric Modulators

Molecular pharmacology, 2018-05, Vol.93 (5), p.526-540

2018

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Quantification of the interrelationships of receptor pharmacologies within a tricyclic privileged structural scaffold through application of modified forward selection

Neuropharmacology, 2014-02, Vol.77, p.475-480

2014

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Neuroprotective Agents and Cerebral Ischaemia

1, 1996

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Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice

European journal of nuclear medicine and molecular imaging, 2004-08, Vol.31 (8), p.1136-1145

2004

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The effects of the nonselective benzodiazepine lorazepam and the α2/α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels

Clinical pharmacology in drug development, 2015-03, Vol.4 (2), p.149-154

2015

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Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia

Neuron (Cambridge, Mass.), 2019-07, Vol.103 (2), p.203-216.e8

2019

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Investigating the neuroimmunogenic architecture of schizophrenia

Molecular psychiatry, 2018-05, Vol.23 (5), p.1251-1260

2018

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Spontaneous Orofacial Dyskinesia and Dopaminergic Function in Rats after 6 Months of Neuroleptic Treatment

Science (American Association for the Advancement of Science), 1983-04, Vol.220 (4596), p.530-532

1983

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Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods

Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19)

Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

Metabotropic Glutamate Receptors 2 and 3 as Targets for Treating Nicotine Addiction

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs

From bench to bedside: mGluR2 positive allosteric modulators as medications to treat substance use disorders

The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats

Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia

The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys

BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders

Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators

Derisking Psychiatric Drug Development: The NIMH's Fast Fail Program, A Novel Precompetitive Model

The central nervous system effects of the partial GABA‐Aα2,3‐selective receptor modulator AZD7325 in comparison with lorazepam in healthy males

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening

Alzheimer's disease research and development: a call for a new research roadmap

AZD6280, a novel partial γ-aminobutyric acid A receptor modulator, demonstrates a pharmacodynamically selective effect profile in healthy male volunteers

Differential Pharmacology and Binding of mGlu 2 Receptor Allosteric Modulators

Quantification of the interrelationships of receptor pharmacologies within a tricyclic privileged structural scaffold through application of modified forward selection

Neuroprotective Agents and Cerebral Ischaemia

Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice

The effects of the nonselective benzodiazepine lorazepam and the α2/α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels

Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia

Investigating the neuroimmunogenic architecture of schizophrenia

Spontaneous Orofacial Dyskinesia and Dopaminergic Function in Rats after 6 Months of Neuroleptic Treatment

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