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Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy

Life sciences (1973), 2018-01, Vol.192, p.151-159

2018

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A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse

Biochemical pharmacology, 2002-01, Vol.63 (2), p.89-98

2002

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Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery

The Journal of pharmacology and experimental therapeutics, 2001-08, Vol.298 (2), p.395

2001

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The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L

Anticancer research, 1998-05, Vol.18 (3A), p.1527

1998

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Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes

Anti-cancer drugs, 2004-04, Vol.15 (4), p.389-399

2004

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High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed ( Nigella sativa L.)

Journal of pharmaceutical and biomedical analysis, 1999-04, Vol.19 (5), p.757-762

1999

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Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: Affinity for neuronal nicotinic acetylcholine receptors

Life sciences (1973), 2005-12, Vol.78 (5), p.495-505

2005

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Defunctionalized Lobeline Analogues: Structure−Activity of Novel Ligands for the Vesicular Monoamine Transporter

Journal of medicinal chemistry, 2005-08, Vol.48 (17), p.5551-5560

2005

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Accumulation of nicotine and its metabolites in rat brain after intermittent or continuous peripheral administration of [2'-(14)C]nicotine

Drug metabolism and disposition, 2001-05, Vol.29 (5), p.645

2001

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Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats

Psychopharmacology, 2006-02, Vol.184 (3-4), p.426-434

2006

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Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters

The Journal of pharmacology and experimental therapeutics, 2004-09, Vol.310 (3), p.1035

2004

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Lobeline attenuates d-methamphetamine self-administration in rats

The Journal of pharmacology and experimental therapeutics, 2001-07, Vol.298 (1), p.172

2001

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QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release

Bioorganic & medicinal chemistry, 2006-05, Vol.14 (9), p.3017-3037

2006

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Nornicotine is self-administered intravenously by rats

Psychopharmacologia, 1999-10, Vol.146 (3), p.290-296

1999

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NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols

Cancer research (Chicago, Ill.), 2003-09, Vol.63 (17), p.5636-5645

2003

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Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood-brain barrier choline transporter

The Journal of pharmacology and experimental therapeutics, 2003-03, Vol.304 (3), p.1268

2003

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Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine

Drug metabolism and disposition, 1999-12, Vol.27 (12), p.1448

1999

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Toxicity of Dipyridyl Compounds and Related Compounds

Critical reviews in toxicology, 2004-09, Vol.34 (5), p.447-460

2004

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Indirect Trapping of the Retroconjugate Addition Reaction Intermediate Involved in the Epimerization of Lobeline: Application to the Synthesis of (−)-Sedamine

Journal of organic chemistry, 2004-11, Vol.69 (24), p.8514-8517

2004

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Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism

Psychopharmacologia, 2001-08, Vol.156 (4), p.469-476

2001

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In vitro/in vivo correlation of transdermal naltrexone prodrugs in hairless guinea pigs

Pharmaceutical research, 2005-06, Vol.22 (6), p.981-989

2005

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Lobeline Displaces [3H]Dihydrotetrabenazine Binding and Releases [3H]Dopamine from Rat Striatal Synaptic Vesicles: Comparison with d‐Amphetamine

Journal of neurochemistry, 1998-07, Vol.71 (1), p.258-265

1998

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(S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner

The Journal of pharmacology and experimental therapeutics, 1999-03, Vol.288 (3), p.905

1999

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Effects of a lobelane analog on [11C]DTBZ binding to the VMAT2

NeuroImage (Orlando, Fla.), 2010-08, Vol.52 (S1), p.S68-S68

2010

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Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking

Biochemical pharmacology, 1997-10, Vol.54 (7), p.743-753

1997

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Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy

A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse

Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery

The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L

Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes

High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed ( Nigella sativa L.)

Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: Affinity for neuronal nicotinic acetylcholine receptors

Defunctionalized Lobeline Analogues: Structure−Activity of Novel Ligands for the Vesicular Monoamine Transporter

Accumulation of nicotine and its metabolites in rat brain after intermittent or continuous peripheral administration of [2'-(14)C]nicotine

Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats

Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters

Lobeline attenuates d-methamphetamine self-administration in rats

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release

Nornicotine is self-administered intravenously by rats

NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols

Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood-brain barrier choline transporter

Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine

Toxicity of Dipyridyl Compounds and Related Compounds

Indirect Trapping of the Retroconjugate Addition Reaction Intermediate Involved in the Epimerization of Lobeline: Application to the Synthesis of (−)-Sedamine

Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism

In vitro/in vivo correlation of transdermal naltrexone prodrugs in hairless guinea pigs

Lobeline Displaces [3H]Dihydrotetrabenazine Binding and Releases [3H]Dopamine from Rat Striatal Synaptic Vesicles: Comparison with d‐Amphetamine

(S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner

Effects of a lobelane analog on [11C]DTBZ binding to the VMAT2

Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking

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