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Vaccination with Genetically Engineered Allergens Prevents Progression of Allergic Disease

Proceedings of the National Academy of Sciences - PNAS, 2004-10, Vol.101 (Suppl 2), p.14677-14682

2004

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Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives

Clinical and experimental allergy, 2008-09, Vol.38 (9), p.1514-1525

2008

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Efficacy and safety of preseasonal‐specific immunotherapy with an aluminium‐adsorbed six‐grass pollen allergoid

Allergy (Copenhagen), 2005-06, Vol.60 (6), p.801-807

2005

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Characterization of a Hypoallergenic Recombinant Bet v 1 Variant as a Candidate for Allergen-Specific Immunotherapy

International archives of allergy and immunology, 2008-01, Vol.145 (3), p.193-206

2008

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Different allergenic activity of grass pollen allergens revealed by skin testing

European journal of clinical investigation, 2008-04, Vol.38 (4), p.260-267

2008

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Isoallergen Analysis of Pectate Lyases (Amb a 1 and Amb a 2) from Commercial Short Ragweed Pollen

Journal of allergy and clinical immunology, 2011-02, Vol.127 (2), p.AB168-AB168

2011

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Measurement of basophil-activating capacity of grass pollen allergens, allergoids and hypoallergenic recombinant derivatives by flow cytometry using anti-CD203c

Clinical and experimental allergy, 2003-09, Vol.33 (9), p.1266-1272

2003

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Identification of T-Cell Epitopes of Phl p 5a as a Basic Requirement for Construction of Hypoallergenic Mutants

Journal of allergy and clinical immunology, 2010-02, Vol.125 (2), p.AB146-AB146

2010

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Bet v 1-specific IgE-, IgG1- and IgG4-Antibody Responses after Immunotherapy with Hypoallergenic rBet v 1 or Birch Pollen Extract

Journal of allergy and clinical immunology, 2008-02, Vol.121 (2), p.S141-S141

2008

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Allergen-specific immunotherapy with recombinant grass pollen allergens

Journal of Allergy and Clinical Immunology, 2005-09, Vol.116 (3), p.608-613

2005

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Purification of Natural Bet v 2 by poly-L-Proline Affinity Chromatography and Preparative SDS-PAGE

Journal of allergy and clinical immunology, 2010-02, Vol.125 (2), p.AB147-AB147

2010

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Rapid method for arrayed investigation of IgE‐reactivity profiles using natural and recombinant allergens

Allergy (Copenhagen), 2002-09, Vol.57 (9), p.821-824

2002

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Vaccines for birch pollen allergy based on genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1

Clinical and experimental allergy, 2004-01, Vol.34 (1), p.115-122

2004

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The European Union Biological Standardization Program: Detailed Characterization of GMP-produced Recombinant Bet v 1.0101 and Phl p 5.0109 as Candidate Reference Standards

Journal of allergy and clinical immunology, 2009-02, Vol.123 (2), p.S216-S216

2009

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Generation of a low Immunoglobulin E-binding mutant of the timothy grass pollen major allergen Phl p 5a

Clinical and experimental allergy, 2007-03, Vol.37 (3), p.441-450

2007

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What are allergens?

Allergy (Copenhagen), 1999-01, Vol.54 (s56), p.7-8

Cromwell, O.

1999

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Immunological Characterization of a Hypoallergenic Folding Variant of rBet v 1

Journal of allergy and clinical immunology, 2006-02, Vol.117 (2), p.S115-S115

2006

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Short-term preseasonal birch pollen allergoid immunotherapy influences symptoms, specific nasal provocation and cytokine levels in nasal secretions, but not peripheral T-cell responses, in patients with allergic rhinitis

Clinical and experimental allergy, 1999-10, Vol.29 (10), p.1326-1335

1999

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T Cell Reactivity with Allergoids: Influence of the Type of APC

The Journal of immunology (1950), 2000-08, Vol.165 (4), p.1807-1815

2000

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Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1β and tumour necrosis factor-α

Immunology, 1992-11, Vol.77 (3), p.330-337

1992

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Platelet-activating factor: a potent chemotactic and chemokinetic factor for human eosinophils

The Journal of clinical investigation, 1986-12, Vol.78 (6), p.1701-1706

1986

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The high molecular mass allergen fraction of timothy grass pollen (Phleum pratense) between 50-60 kDa is comprised of two major allergens: Phl p 4 and Phl p 13

Clinical and experimental allergy, 2000-10, Vol.30 (10), p.1395-1402

2000

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Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma

Journal of allergy and clinical immunology, 1993-12, Vol.92 (6), p.857-868

1993

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The European Union CREATE Project: A model for international standardization of allergy diagnostics and vaccines

Journal of allergy and clinical immunology, 2008-11, Vol.122 (5), p.882-889.e2

2008

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Vaccination with Genetically Engineered Allergens Prevents Progression of Allergic Disease

Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives

Efficacy and safety of preseasonal‐specific immunotherapy with an aluminium‐adsorbed six‐grass pollen allergoid

CREATE Project: development of certified reference materials for allergenic products and validation of methods for their quantification

Characterization of a Hypoallergenic Recombinant Bet v 1 Variant as a Candidate for Allergen-Specific Immunotherapy

Different allergenic activity of grass pollen allergens revealed by skin testing

Isoallergen Analysis of Pectate Lyases (Amb a 1 and Amb a 2) from Commercial Short Ragweed Pollen

Measurement of basophil-activating capacity of grass pollen allergens, allergoids and hypoallergenic recombinant derivatives by flow cytometry using anti-CD203c

Identification of T-Cell Epitopes of Phl p 5a as a Basic Requirement for Construction of Hypoallergenic Mutants

Bet v 1-specific IgE-, IgG1- and IgG4-Antibody Responses after Immunotherapy with Hypoallergenic rBet v 1 or Birch Pollen Extract

Allergen-specific immunotherapy with recombinant grass pollen allergens

Purification of Natural Bet v 2 by poly-L-Proline Affinity Chromatography and Preparative SDS-PAGE

Rapid method for arrayed investigation of IgE‐reactivity profiles using natural and recombinant allergens

Vaccines for birch pollen allergy based on genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1

The European Union Biological Standardization Program: Detailed Characterization of GMP-produced Recombinant Bet v 1.0101 and Phl p 5.0109 as Candidate Reference Standards

Generation of a low Immunoglobulin E-binding mutant of the timothy grass pollen major allergen Phl p 5a

What are allergens?

Immunological Characterization of a Hypoallergenic Folding Variant of rBet v 1

Short-term preseasonal birch pollen allergoid immunotherapy influences symptoms, specific nasal provocation and cytokine levels in nasal secretions, but not peripheral T-cell responses, in patients with allergic rhinitis

T Cell Reactivity with Allergoids: Influence of the Type of APC

Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1β and tumour necrosis factor-α

Platelet-activating factor: a potent chemotactic and chemokinetic factor for human eosinophils

The high molecular mass allergen fraction of timothy grass pollen (Phleum pratense) between 50-60 kDa is comprised of two major allergens: Phl p 4 and Phl p 13

Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma

The European Union CREATE Project: A model for international standardization of allergy diagnostics and vaccines

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