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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Nature communications, 2019-03, Vol.10 (1), p.1373-1373, Article 1373

2019

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ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients

Clinical cancer research, 2016-02, Vol.22 (4), p.993-999

2016

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Genomic dissection and mutation-specific target discovery for breast cancer PIK3CA hotspot mutations

BMC genomics, 2024-05, Vol.25 (1), p.519-519, Article 519

2024

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Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease

Nature communications, 2022-10, Vol.13 (1), p.6036-6036, Article 6036

2022

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Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component

Clinical cancer research, 2017-08, Vol.23 (16), p.4875-4884

2017

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Systemic inhibition of PTPN22 augments anticancer immunity

The Journal of clinical investigation, 2021-09, Vol.131 (17), p.1-15

2021

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PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3K α Inhibitors

Clinical cancer research, 2018-03, Vol.24 (6), p.1426-1435

2018

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TrkA overexpression in non-tumorigenic human breast cell lines confers oncogenic and metastatic properties

Breast cancer research and treatment, 2020-02, Vol.179 (3), p.631-642

2020

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HER2 missense mutations have distinct effects on oncogenic signaling and migration

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (45), p.E6205-E6214

2015

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Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17773-17778

2011

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MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.17606-17611

2014

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An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release

Communications biology, 2024-04, Vol.7 (1), p.441-441, Article 441

2024

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NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (37), p.11583-11588

2015

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Analysis of BRCA2 loss of heterozygosity in tumor tissue using droplet digital polymerase chain reaction

Human pathology, 2014-07, Vol.45 (7), p.1546-1550

2014

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Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

Cancer research (Chicago, Ill.), 2013-06, Vol.73 (11), p.3248-3261

2013

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Circulating tumor DNA in early-stage breast cancer: new directions and potential clinical applications

Clinical advances in hematology & oncology, 2021-03, Vol.19 (3), p.155-161

2021

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CHIP Happens: Clonal Hematopoiesis of Indeterminate Potential and Its Relationship to Solid Tumors

Clinical cancer research, 2023-04, Vol.29 (8), p.1403-1411

2023

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

Oncotarget, 2015-09, Vol.6 (28), p.25240-25251

2015

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The breast is yet to come: current and future utility of circulating tumour DNA in breast cancer

British journal of cancer, 2021-09, Vol.125 (6), p.780-788

2021

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Variant Interpretation in Patients With Metastatic Breast Cancer-Reply

JAMA oncology, 2020-04, Vol.6 (4), p.582

2020

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Abstract 883: Defining the observed mutual exclusivity between SF3B1 and TP53 mutations in cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.883-883

2022

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Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer

Clinical cancer research, 2014-05, Vol.20 (10), p.2643-2650

2014

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Abstract 1498: Fibronectin mediates mutation specific interactions between subclonal populations of mutant PIK3CA and HER2 cells in breast cancer

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1498-1498

2020

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Combined Blockade of Activating ERBB2 Mutations and ER Results in Synthetic Lethality of ER+/HER2 Mutant Breast Cancer

Clinical cancer research, 2019-01, Vol.25 (1), p.277-289

2019

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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients

Genomic dissection and mutation-specific target discovery for breast cancer PIK3CA hotspot mutations

Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease

Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component

Systemic inhibition of PTPN22 augments anticancer immunity

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3K α Inhibitors

TrkA overexpression in non-tumorigenic human breast cell lines confers oncogenic and metastatic properties

HER2 missense mutations have distinct effects on oncogenic signaling and migration

Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer

Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers

An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release

NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability

Analysis of BRCA2 loss of heterozygosity in tumor tissue using droplet digital polymerase chain reaction

Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

Circulating tumor DNA in early-stage breast cancer: new directions and potential clinical applications

CHIP Happens: Clonal Hematopoiesis of Indeterminate Potential and Its Relationship to Solid Tumors

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

The breast is yet to come: current and future utility of circulating tumour DNA in breast cancer

Variant Interpretation in Patients With Metastatic Breast Cancer-Reply

Abstract 883: Defining the observed mutual exclusivity between SF3B1 and TP53 mutations in cancer

Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer

Abstract 1498: Fibronectin mediates mutation specific interactions between subclonal populations of mutant PIK3CA and HER2 cells in breast cancer

Combined Blockade of Activating ERBB2 Mutations and ER Results in Synthetic Lethality of ER+/HER2 Mutant Breast Cancer

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