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Siglecs as positive and negative regulators of the immune system

Biochemical Society transactions, 2008-12, Vol.36 (Pt 6), p.1467-1471

2008

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Siglecs in innate immunity

Current opinion in pharmacology, 2005-08, Vol.5 (4), p.431-437

Crocker, Paul R

2005

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Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell–cell interactions and signalling

Current Opinion in Structural Biology, 2002-10, Vol.12 (5), p.609-615

Crocker, Paul R

2002

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Siglecs, sialic acids and innate immunity

Trends in Immunology, 2001-06, Vol.22 (6), p.337-342

2001

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Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors

Blood, 2006-05, Vol.107 (9), p.3600-3608

2006

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Recognition of sialylated meningococcal lipopolysaccharide by siglecs expressed on myeloid cells leads to enhanced bacterial uptake

Molecular microbiology, 2003-09, Vol.49 (5), p.1213-1225

2003

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Siglec‐F antibody administration to mice selectively reduces blood and tissue eosinophils

Allergy (Copenhagen), 2008-09, Vol.63 (9), p.1156-1163

2008

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Characterization of CD33 as a New Member of the Sialoadhesin Family of Cellular Interaction Molecules

Blood, 1995-04, Vol.85 (8), p.2005-2012

1995

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Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligand

Glycobiology (Oxford), 2005-11, Vol.15 (11), p.1125-1135

2005

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The Membrane-Proximal Immunoreceptor Tyrosine-Based Inhibitory Motif Is Critical for the Inhibitory Signaling Mediated by Siglecs-7 and -9, CD33-Related Siglecs Expressed on Human Monocytes and NK Cells

The Journal of immunology (1950), 2004-12, Vol.173 (11), p.6841-6849

2004

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Siglecs in the immune system

Immunology, 2001-06, Vol.103 (2), p.137-145

2001

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The murine inhibitory receptor mSiglec‐E is expressed broadly on cells of the innate immune system whereas mSiglec‐F is restricted to eosinophils

European journal of immunology, 2004-04, Vol.34 (4), p.1175-1184

2004

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Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec‐7‐dependent and ‐independent mechanisms

European journal of immunology, 2003-06, Vol.33 (6), p.1642-1648

2003

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A school-based exercise intervention augments bone mineral accrual in early pubertal girls

The Journal of pediatrics, 2001-10, Vol.139 (4), p.501-508

2001

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Sialoadhesin-Deficient Mice Exhibit Subtle Changes in B- and T-Cell Populations and Reduced Immunoglobulin M Levels

Molecular and Cellular Biology, 2006-02, Vol.26 (4), p.1549-1557

2006

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Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations

Blood, 2001-01, Vol.97 (1), p.288-296

2001

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Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein

The Journal of biological chemistry, 2003-08, Vol.278 (33), p.31007-31019

2003

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Carbohydrate microarrays reveal sulphation as a modulator of siglec binding

Biochemical and biophysical research communications, 2006-06, Vol.344 (4), p.1141-1146

2006

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Siglec-5 (CD170) Can Mediate Inhibitory Signaling in the Absence of Immunoreceptor Tyrosine-based Inhibitory Motif Phosphorylation

The Journal of biological chemistry, 2005-05, Vol.280 (20), p.19843-19851

2005

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A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9

The Journal of biological chemistry, 2002-02, Vol.277 (8), p.6324-6332

2002

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Siglec-9, a Novel Sialic Acid Binding Member of the Immunoglobulin Superfamily Expressed Broadly on Human Blood Leukocytes

The Journal of biological chemistry, 2000-07, Vol.275 (29), p.22121-22126

2000

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Carbohydrate recognition systems: functional triads in cell—cell interactions

Current opinion in structural biology, 1996-10, Vol.6 (5), p.679-691

1996

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Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells

Allergy (Copenhagen), 2006-06, Vol.61 (6), p.769-776

2006

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Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia

The Journal of biological chemistry, 2002-07, Vol.277 (27), p.24466-24474

2002

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Negative regulation of leucocyte functions by CD33-related siglecs

Biochemical Society transactions, 2006-12, Vol.34 (Pt 6), p.1024-1027

2006

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Siglecs as positive and negative regulators of the immune system

Siglecs in innate immunity

Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell–cell interactions and signalling

Siglecs, sialic acids and innate immunity

Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors

Recognition of sialylated meningococcal lipopolysaccharide by siglecs expressed on myeloid cells leads to enhanced bacterial uptake

Siglec‐F antibody administration to mice selectively reduces blood and tissue eosinophils

Characterization of CD33 as a New Member of the Sialoadhesin Family of Cellular Interaction Molecules

Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligand

The Membrane-Proximal Immunoreceptor Tyrosine-Based Inhibitory Motif Is Critical for the Inhibitory Signaling Mediated by Siglecs-7 and -9, CD33-Related Siglecs Expressed on Human Monocytes and NK Cells

Siglecs in the immune system

The murine inhibitory receptor mSiglec‐E is expressed broadly on cells of the innate immune system whereas mSiglec‐F is restricted to eosinophils

Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec‐7‐dependent and ‐independent mechanisms

A school-based exercise intervention augments bone mineral accrual in early pubertal girls

Sialoadhesin-Deficient Mice Exhibit Subtle Changes in B- and T-Cell Populations and Reduced Immunoglobulin M Levels

Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations

Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein

Carbohydrate microarrays reveal sulphation as a modulator of siglec binding

Siglec-5 (CD170) Can Mediate Inhibitory Signaling in the Absence of Immunoreceptor Tyrosine-based Inhibitory Motif Phosphorylation

A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9

Siglec-9, a Novel Sialic Acid Binding Member of the Immunoglobulin Superfamily Expressed Broadly on Human Blood Leukocytes

Carbohydrate recognition systems: functional triads in cell—cell interactions

Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells

Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia

Negative regulation of leucocyte functions by CD33-related siglecs

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