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Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

Immunity (Cambridge, Mass.), 2012-03, Vol.36 (3), p.322-335

2012

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Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration

Immunity (Cambridge, Mass.), 2012-08, Vol.37 (2), p.249-263

2012

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Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

Cell, 2014-02, Vol.156 (4), p.744-758

2014

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Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease

Cancer research (Chicago, Ill.), 2013-02, Vol.73 (3), p.1107-1117

2013

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Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors

Leukemia, 2017-02, Vol.31 (2), p.479-490

2017

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Hypoxia Supports Differentiation of Terminally Exhausted CD8 T Cells

Frontiers in immunology, 2021-05, Vol.12, p.660944-660944

2021

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Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment

Glycobiology (Oxford), 2014-12, Vol.24 (12), p.1283-1290

2014

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Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment

Cellular immunology, 2018-11, Vol.333, p.34-45

2018

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Galectins as potential therapeutic targets in STIs in the female genital tract

Nature reviews. Urology, 2022-04, Vol.19 (4), p.240-252

2022

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Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

Nature immunology, 2007-08, Vol.8 (8), p.825-834

2007

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A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease

Cancer research (Chicago, Ill.), 2013, Vol.73 (1), p.86-96

2013

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Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression

Journal of leukocyte biology, 2012-02, Vol.91 (2), p.321-331

2012

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Galectins as Emerging Glyco-Checkpoints and Therapeutic Targets in Glioblastoma

International journal of molecular sciences, 2021-12, Vol.23 (1), p.316

2021

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Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

Cell death and differentiation, 2023-04, Vol.30 (4), p.906-921

2023

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Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

Cancer Immunology, Immunotherapy, 2007-11, Vol.56 (11), p.1687-1700

2007

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Targeting galectin-driven regulatory circuits in cancer and fibrosis

Nature reviews. Drug discovery, 2023-04, Vol.22 (4), p.295-316

2023

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Tumor immune escape mechanisms that operate during metastasis

Current pharmaceutical biotechnology, 2011-11, Vol.12 (11), p.1923-1936

2011

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Modulation of endothelial cell migration and angiogenesis: a novel function for the “tandem‐repeat” lectin galectin‐8

The FASEB journal, 2011-01, Vol.25 (1), p.242-254

2011

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Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia

Haematologica (Roma), 2020-09, Vol.105 (9), p.e465-469

2020

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Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweet

Pharmacological research, 2016-07, Vol.109, p.45-54

2016

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Extracellular vesicles from human plasma dampen inflammation and promote tissue repair functions in macrophages

Journal of extracellular vesicles, 2023-06, Vol.12 (6), p.e12331-n/a

2023

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Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

The Journal of experimental medicine, 2012-10, Vol.209 (11), p.1985-2000

2012

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Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

Trends in biochemical sciences (Amsterdam. Regular ed.), 2017-04, Vol.42 (4), p.255-273

2017

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Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8 + regulatory T cells

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (21), p.1

2021

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Tumor Necrosis Factor Receptor-1 (p55) Deficiency Attenuates Tumor Growth and Intratumoral Angiogenesis and Stimulates CD8 + T Cell Function in Melanoma

Cells (Basel, Switzerland), 2020-11, Vol.9 (11), p.2469

2020

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Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration

Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease

Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors

Hypoxia Supports Differentiation of Terminally Exhausted CD8 T Cells

Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment

Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment

Galectins as potential therapeutic targets in STIs in the female genital tract

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression

Galectins as Emerging Glyco-Checkpoints and Therapeutic Targets in Glioblastoma

Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

Targeting galectin-driven regulatory circuits in cancer and fibrosis

Tumor immune escape mechanisms that operate during metastasis

Modulation of endothelial cell migration and angiogenesis: a novel function for the “tandem‐repeat” lectin galectin‐8

Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia

Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweet

Extracellular vesicles from human plasma dampen inflammation and promote tissue repair functions in macrophages

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8 + regulatory T cells

Tumor Necrosis Factor Receptor-1 (p55) Deficiency Attenuates Tumor Growth and Intratumoral Angiogenesis and Stimulates CD8 + T Cell Function in Melanoma

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