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Expanding the scope of novel 1,2,3-triazole derivatives as new antiparasitic drug candidates

RSC medicinal chemistry, 2023-01, Vol.14 (1), p.122-134

2023

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The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake

PLoS neglected tropical diseases, 2016-01, Vol.10 (1), p.e0004359-e0004359

2016

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Targeting L-Proline Uptake as New Strategy for Anti-chagas Drug Development

Frontiers in chemistry, 2020-08, Vol.8, p.696-696

2020

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A new model for Trypanosoma cruzi heme homeostasis depends on modulation of TcHTE protein expression

The Journal of biological chemistry, 2020-09, Vol.295 (38), p.13202-13212

2020

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Role of Heme and Heme-Proteins in Trypanosomatid Essential Metabolic Pathways

Enzyme Research, 2011, Vol.2011, p.873230-12

2011

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Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly

The EMBO journal, 2007-10, Vol.26 (20), p.4335-4346

2007

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Heme A synthesis and CcO activity are essential for Trypanosoma cruzi infectivity and replication

Biochemical journal, 2017-07, Vol.474 (14), p.2315-2332

2017

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Heme A synthesis and C c O activity are essential for Trypanosoma cruzi infectivity and replication

Biochemical journal, 2017-07, Vol.474 (14), p.2315-2332

2017

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Biosynthesis of heme O in intraerythrocytic stages of Plasmodium falciparum and potential inhibitors of this pathway

Scientific reports, 2019-12, Vol.9 (1), p.19261-13, Article 19261

2019

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Metallo-β-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions

Nature chemical biology, 2012-08, Vol.8 (8), p.698-700

2012

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The heme uptake process in Trypanosoma cruzi epimastigotes is inhibited by heme analogues and by inhibitors of ABC transporters

Acta tropica, 2011-12, Vol.120 (3), p.211-218

2011

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Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae

FEMS microbiology letters, 2010-11, Vol.312 (2), p.133-141

2010

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Spectroscopic Characterization of a Binuclear Metal Site in Bacillus cereus β-Lactamase II

Biochemistry (Easton), 1998-07, Vol.37 (28), p.10173-10180

1998

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Heme O Synthase and Heme A Synthase from Bacillus subtilis and Rhodobacter sphaeroides Interact in Escherichia coli

Biochemistry (Easton), 2004-10, Vol.43 (42), p.13541-13548

2004

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Axial Ligand Modulation of the Electronic Structures of Binuclear Copper Sites: Analysis of Paramagnetic 1H NMR Spectra of Met160Gln CuA

Journal of the American Chemical Society, 2001-11, Vol.123 (47), p.11678-11685

2001

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A new model for Trypanosoma cruzi heme homeostasis depends on modulation of Tc HTE protein expression

The Journal of biological chemistry, 2020-09, Vol.295 (38), p.13202

2020

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The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake: e0004359

PLoS neglected tropical diseases, 2016-01, Vol.10 (1)

2016

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Is there a bridging ligand in metal-substituted zinc β-lactamases? A spectroscopic and theoretical answer

International journal of quantum chemistry, 2002, Vol.88 (1), p.118-132

2002

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The Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae: Identification of heme A biosynthesis pathway in T. cruzi

FEMS microbiology letters, 2010-11, Vol.312 (2), p.133-141

2010

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The Trypanosoma cruziproteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae

FEMS microbiology letters, 2010, Vol.312 (2), p.133-141

2010

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Class B beta-lactamases: the importance of being metallic

Current pharmaceutical design, 1999-11, Vol.5 (11), p.915-927

1999

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Metallo-β-lactamases: does it take two to tango?

Coordination chemistry reviews, 1999-09, Vol.190, p.519-535

1999

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Axial Ligand Modulation of the Electronic Structures of Binuclear Copper Sites: Analysis of Paramagnetic 1 H NMR Spectra of Met160Gln Cu A

Journal of the American Chemical Society, 2001-11, Vol.123 (47), p.11678-11685

2001

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Synthesis and elastase inhibitory activity of 6α-chloro-2,2-dimethyl-3α-(pivaloyloxy)methylpenam sulfone, 6α-chloro-2,2-dimethyl-3- exo-methylenepenam sulfone, benzyl and methyl 6α-substituted penicillanate sulfones

Bioorganic & medicinal chemistry, 1995, Vol.3 (1), p.95-100

1995

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Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones

Bioorganic & medicinal chemistry letters, 1995-09, Vol.5 (17), p.2033-2036

1995

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Expanding the scope of novel 1,2,3-triazole derivatives as new antiparasitic drug candidates

The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake

Targeting L-Proline Uptake as New Strategy for Anti-chagas Drug Development

A new model for Trypanosoma cruzi heme homeostasis depends on modulation of TcHTE protein expression

Role of Heme and Heme-Proteins in Trypanosomatid Essential Metabolic Pathways

Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly

Heme A synthesis and CcO activity are essential for Trypanosoma cruzi infectivity and replication

Heme A synthesis and C c O activity are essential for Trypanosoma cruzi infectivity and replication

Biosynthesis of heme O in intraerythrocytic stages of Plasmodium falciparum and potential inhibitors of this pathway

Metallo-β-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions

The heme uptake process in Trypanosoma cruzi epimastigotes is inhibited by heme analogues and by inhibitors of ABC transporters

Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae

Spectroscopic Characterization of a Binuclear Metal Site in Bacillus cereus β-Lactamase II

Heme O Synthase and Heme A Synthase from Bacillus subtilis and Rhodobacter sphaeroides Interact in Escherichia coli

Axial Ligand Modulation of the Electronic Structures of Binuclear Copper Sites: Analysis of Paramagnetic 1H NMR Spectra of Met160Gln CuA

A new model for Trypanosoma cruzi heme homeostasis depends on modulation of Tc HTE protein expression

The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake: e0004359

Is there a bridging ligand in metal-substituted zinc β-lactamases? A spectroscopic and theoretical answer

The Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae: Identification of heme A biosynthesis pathway in T. cruzi

The Trypanosoma cruziproteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae

Class B beta-lactamases: the importance of being metallic

Metallo-β-lactamases: does it take two to tango?

Axial Ligand Modulation of the Electronic Structures of Binuclear Copper Sites: Analysis of Paramagnetic 1 H NMR Spectra of Met160Gln Cu A

Synthesis and elastase inhibitory activity of 6α-chloro-2,2-dimethyl-3α-(pivaloyloxy)methylpenam sulfone, 6α-chloro-2,2-dimethyl-3- exo-methylenepenam sulfone, benzyl and methyl 6α-substituted penicillanate sulfones

Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones

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