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Asymptomatic hyperuricaemia: a silent activator of the innate immune system

Nature reviews. Rheumatology, 2020-02, Vol.16 (2), p.75-86

2020

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Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia

Immunological reviews, 2020-03, Vol.294 (1), p.92-105

2020

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Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (21), p.5485-5490

2017

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Inflammasome-independent modulation of cytokine response by autophagy in human cells

PloS one, 2011-04, Vol.6 (4), p.e18666-e18666

2011

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GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells

Scientific reports, 2024-02, Vol.14 (1), p.3565-3565, Article 3565

2024

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Enhanced Innate and Acquired Immune Responses in Systemic Sclerosis Primary Peripheral Blood Mononuclear Cells (PBMCs)

International journal of molecular sciences, 2023-10, Vol.24 (19), p.14438

2023

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Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Annals of the rheumatic diseases, 2016-03, Vol.75 (3), p.593-600

2016

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TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Arthritis research & therapy, 2023-02, Vol.25 (1), p.30-30, Article 30

2023

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Detection of Novel Biomarkers in Pediatric Autoimmune Hepatitis by Proteomic Profiling

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7479

2023

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Innate immune memory: Implications for host responses to damage‐associated molecular patterns

European journal of immunology, 2016-04, Vol.46 (4), p.817-828

2016

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Soluble urate-induced effects on cytokine production in vitro - Assessment of methodologies and cell types

Cytokine (Philadelphia, Pa.), 2024-03, Vol.175, p.156502-156502, Article 156502

2024

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Factors modulating the inflammatory response in acute gouty arthritis

Current opinion in rheumatology, 2017-03, Vol.29 (2), p.163-170

2017

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Immune Profiling of Patients with Systemic Sclerosis through Targeted Proteomic Analysis

International journal of molecular sciences, 2023-12, Vol.24 (24), p.17601

2023

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Trained immunity and inflammation in rheumatic diseases

Joint, bone, spine : revue du rhumatisme, 2022-07, Vol.89 (4), p.105364-105364, Article 105364

2022

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The pathogenesis of gout: molecular insights from genetic, epigenomic and transcriptomic studies

Nature reviews. Rheumatology, 2024-08, Vol.20 (8), p.510-523

2024

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A functional genomics approach reveals suggestive quantitative trait loci associated with combined TLR4 and BCP crystal-induced inflammation and osteoarthritis

Osteoarthritis and cartilage, 2023-08, Vol.31 (8), p.1022-1034

2023

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Regulation of SOCS3-STAT3 in urate-induced cytokine production in human myeloid cells

Joint, bone, spine : revue du rhumatisme, 2024-05, Vol.91 (3), p.105698-105698, Article 105698

2024

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Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

Annals of the rheumatic diseases, 2020-04, Vol.79 (4), p.536-544

2020

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Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination

Vaccines (Basel), 2024-07, Vol.12 (7), p.736

2024

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Hyperuricemia remodels the serum proteome toward a higher inflammatory state

iScience, 2023-10, Vol.26 (10), p.107909-107909, Article 107909

2023

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Lysine methyltransferase G9a is an important modulator of trained immunity

Clinical & translational immunology, 2021, Vol.10 (2), p.e1253-n/a

2021

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Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

Annals of the rheumatic diseases, 2016-04, Vol.75 (4), p.755-762

2016

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Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra

Annals of the rheumatic diseases, 2016-06, Vol.75 (6), p.1219-1227

2016

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Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients

Immunity, Inflammation and Disease, 2022-11, Vol.10 (11), p.e712-n/a

2022

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TLR1 polymorphisms in Europeans and spontaneous pregnancy loss

Gene, 2012-02, Vol.494 (1), p.109-111

2012

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Asymptomatic hyperuricaemia: a silent activator of the innate immune system

Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia

Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway

Inflammasome-independent modulation of cytokine response by autophagy in human cells

GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells

Enhanced Innate and Acquired Immune Responses in Systemic Sclerosis Primary Peripheral Blood Mononuclear Cells (PBMCs)

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Detection of Novel Biomarkers in Pediatric Autoimmune Hepatitis by Proteomic Profiling

Innate immune memory: Implications for host responses to damage‐associated molecular patterns

Soluble urate-induced effects on cytokine production in vitro - Assessment of methodologies and cell types

Factors modulating the inflammatory response in acute gouty arthritis

Immune Profiling of Patients with Systemic Sclerosis through Targeted Proteomic Analysis

Trained immunity and inflammation in rheumatic diseases

The pathogenesis of gout: molecular insights from genetic, epigenomic and transcriptomic studies

A functional genomics approach reveals suggestive quantitative trait loci associated with combined TLR4 and BCP crystal-induced inflammation and osteoarthritis

Regulation of SOCS3-STAT3 in urate-induced cytokine production in human myeloid cells

Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination

Hyperuricemia remodels the serum proteome toward a higher inflammatory state

Lysine methyltransferase G9a is an important modulator of trained immunity

Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra

Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients

TLR1 polymorphisms in Europeans and spontaneous pregnancy loss

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