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Converging cellular themes for the hereditary spastic paraplegias

Current opinion in neurobiology, 2018-08, Vol.51, p.139-146

Blackstone, Craig

2018

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Cellular Pathways of Hereditary Spastic Paraplegia

Annual review of neuroscience, 2012-01, Vol.35 (1), p.25-47

BLACKSTONE, Craig

2012

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Untangling the web: Mechanisms underlying ER network formation

Biochimica et biophysica acta, 2013-11, Vol.1833 (11), p.2492-2498

2013

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Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

Annals of the New York Academy of Sciences, 2010-07, Vol.1201 (1), p.34-39

2010

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Cyclic AMP-dependent Protein Kinase Phosphorylation of Drp1 Regulates Its GTPase Activity and Mitochondrial Morphology

The Journal of biological chemistry, 2007-07, Vol.282 (30), p.21583-21587

2007

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FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

Nature communications, 2016-03, Vol.7 (1), p.10939-10939, Article 10939

2016

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ER proteins decipher the tubulin code to regulate organelle distribution

Nature (London), 2022-01, Vol.601 (7891), p.132-138

2022

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Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

Science (American Association for the Advancement of Science), 2016-10, Vol.354 (6311), p.433-433

2016

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Hereditary spastic paraplegias: membrane traffic and the motor pathway

Nature reviews. Neuroscience, 2011-01, Vol.12 (1), p.31-42

2011

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Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome

PLoS biology, 2016-07, Vol.14 (7), p.e1002511-e1002511

2016

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Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

The Journal of cell biology, 2019-08, Vol.218 (8), p.2583-2599

2019

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Further assembly required: construction and dynamics of the endoplasmic reticulum network

EMBO reports, 2010-07, Vol.11 (7), p.515-521

2010

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A Larger BAT Improves Metabolism but Whiffs on Safety

EBioMedicine, 2017-10, Vol.24 (C), p.9-10

Blackstone, Craig

2017

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Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.14954-14959

2013

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Hereditary spastic paraplegia

Handbook of Clinical Neurology, 2018, Vol.148, p.633-652

Blackstone, Craig

2018

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Loss of Spastin Function Results in Disease‐Specific Axonal Defects in Human Pluripotent Stem Cell‐Based Models of Hereditary Spastic Paraplegia

Stem cells (Dayton, Ohio), 2014-02, Vol.32 (2), p.414-423

2014

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Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria

Nature communications, 2022-03, Vol.13 (1), p.1582-1582, Article 1582

2022

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Emerging themes of ER organization in the development and maintenance of axons

Current opinion in neurobiology, 2010-10, Vol.20 (5), p.531-537

2010

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Importance of genetic testing for childhood‐onset hereditary spastic paraplegia

Developmental medicine and child neurology, 2023-03, Vol.65 (3), p.307-308

Blackstone, Craig

2023

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Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

Nature structural & molecular biology, 2008-12, Vol.15 (12), p.1278-1286

2008

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Hereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion

Science signaling, 2020-01, Vol.13 (613)

2020

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Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A

Human molecular genetics, 2014-11, Vol.23 (21), p.5638-5648

2014

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Clinical Trial Designs and Measures in Hereditary Spastic Paraplegias

Frontiers in neurology, 2018-12, Vol.9, p.1017-1017

2018

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Early‐onset hereditary spastic paraplegia: the possibility of a genetic diagnosis

Developmental medicine and child neurology, 2020-09, Vol.62 (9), p.1011-1011

Blackstone, Craig

2020

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Atlastin Endoplasmic Reticulum-Shaping Proteins Facilitate Zika Virus Replication

Journal of virology, 2019-12, Vol.93 (23)

2019

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Converging cellular themes for the hereditary spastic paraplegias

Cellular Pathways of Hereditary Spastic Paraplegia

Untangling the web: Mechanisms underlying ER network formation

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

Cyclic AMP-dependent Protein Kinase Phosphorylation of Drp1 Regulates Its GTPase Activity and Mitochondrial Morphology

FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

ER proteins decipher the tubulin code to regulate organelle distribution

Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

Hereditary spastic paraplegias: membrane traffic and the motor pathway

Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

Further assembly required: construction and dynamics of the endoplasmic reticulum network

A Larger BAT Improves Metabolism but Whiffs on Safety

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation

Hereditary spastic paraplegia

Loss of Spastin Function Results in Disease‐Specific Axonal Defects in Human Pluripotent Stem Cell‐Based Models of Hereditary Spastic Paraplegia

Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria

Emerging themes of ER organization in the development and maintenance of axons

Importance of genetic testing for childhood‐onset hereditary spastic paraplegia

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

Hereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion

Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A

Clinical Trial Designs and Measures in Hereditary Spastic Paraplegias

Early‐onset hereditary spastic paraplegia: the possibility of a genetic diagnosis

Atlastin Endoplasmic Reticulum-Shaping Proteins Facilitate Zika Virus Replication

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