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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4400-4405

2011

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Randomized, Double-Blind, Multicenter Phase 2 Study Comparing the Efficacy and Safety of Oral Solithromycin (CEM-101) to Those of Oral Levofloxacin in the Treatment of Patients with Community-Acquired Bacterial Pneumonia

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2526-2534

2013

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Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials

Malaria journal, 2013-02, Vol.12 (1), p.70-70, Article 70

2013

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In Vitro and In Vivo Activity of Solithromycin (CEM-101) against Plasmodium Species

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.703-707

2012

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A Randomized, Double-Blind Phase 2 Study Comparing the Efficacy and Safety of an Oral Fusidic Acid Loading-Dose Regimen to Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Clinical infectious diseases, 2011-06, Vol.52 (suppl_7), p.S520-S526

2011

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Phase 3 trial of treating gonorrhoea with solithromycin

The Lancet infectious diseases, 2019-09, Vol.19 (9), p.928-928

2019

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Challenges facing drug development for malaria

Current opinion in microbiology, 2008-10, Vol.11 (5), p.428-433

Craft, J Carl

2008

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Review of pyronaridine anti-malarial properties and product characteristics

Malaria journal, 2012-08, Vol.11 (1), p.270-270, Article 270

2012

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First‐in‐man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

British journal of clinical pharmacology, 2013-02, Vol.75 (2), p.535-548

2013

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Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate

The Pediatric infectious disease journal, 1995-06, Vol.14 (6), p.471-477

1995

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Comparative embryotoxicity of different antimalarial peroxides: In vitro study using the rat whole embryo culture model (WEC)

Reproductive toxicology (Elmsford, N.Y.), 2010-12, Vol.30 (4), p.583-590

2010

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Macrolide Therapy of Group A Streptococcal Pharyngitis: 10 Days of Macrolide Therapy (Clarithromycin) Is More Effective in Streptococcal Eradication than 5 Days (Azithromycin)

Clinical infectious diseases, 2001-06, Vol.32 (12), p.1798-1802

2001

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Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Malaria journal, 2009-12, Vol.8 (1), p.304-304, Article 304

2009

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A Randomized Trial of Clarithromycin as Prophylaxis against Disseminated Mycobacterium avium Complex Infection in Patients with Advanced Acquired Immunodeficiency Syndrome

The New England journal of medicine, 1996-08, Vol.335 (6), p.384-391

1996

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Clarithromycin Resistance and Susceptibility Patterns of Mycobacterium avium Strains Isolated During Prophylaxis for Disseminated Infection in Patients with AIDS

Clinical infectious diseases, 1998-10, Vol.27 (4), p.807-812

1998

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Clarithromycin and ethambutol with or without clofazimine for the treatment of bacteremic Mycobacterium avium complex disease in patients with HIV infection

AIDS (London), 1997-03, Vol.11 (3), p.311-317

1997

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Medicines for Malaria Venture new developments in antimalarials

Travel medicine and infectious disease, 2004-08, Vol.2 (3), p.161-170

2004

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Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

The Lancet (British edition), 2010-04, Vol.375 (9724), p.1457-1467

2010

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Steady-State Pharmacokinetics and Electrocardiographic Pharmacodynamics of Clarithromycin and Loratadine after Individual or Concomitant Administration

Antimicrobial Agents and Chemotherapy, 1998-05, Vol.42 (5), p.1176-1180

1998

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Ketolide ABT-773 is active against Toxoplasma gondii

Journal of antimicrobial chemotherapy, 2000-09, Vol.46 (3), p.489-492

2000

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Overview of the tolerability profile of clarithromycin in preclinical and clinical trials

Drug safety, 1993-05, Vol.8 (5), p.350-364

1993

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Overview of the safety profile of clarithromycin suspension in pediatric patients

The Pediatric infectious disease journal, 1993-12, Vol.12 (12 Suppl 3), p.S142-S147

1993

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Ancillary benefits of Mycobacterium avium-intracellulare complex prophylaxis with clarithromycin in HIV-infected patients

Drugs (Basel), 1997, Vol.54 (Supplement 2), p.16-22

1997

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A Randomized, Double-Blind Phase 2 Study Comparing the Efficacy and Safety of an Oral Fusidic Acid Loading-Dose Regimen to Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections: Fusidic Acid Enters the United States

Clinical infectious diseases, 2011, Vol.52

2011

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Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults

The Pediatric infectious disease journal, 1993-12, Vol.12 (12 Suppl 3), p.S106-S111

1993

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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

Randomized, Double-Blind, Multicenter Phase 2 Study Comparing the Efficacy and Safety of Oral Solithromycin (CEM-101) to Those of Oral Levofloxacin in the Treatment of Patients with Community-Acquired Bacterial Pneumonia

Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials

In Vitro and In Vivo Activity of Solithromycin (CEM-101) against Plasmodium Species

A Randomized, Double-Blind Phase 2 Study Comparing the Efficacy and Safety of an Oral Fusidic Acid Loading-Dose Regimen to Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Phase 3 trial of treating gonorrhoea with solithromycin

Challenges facing drug development for malaria

Review of pyronaridine anti-malarial properties and product characteristics

First‐in‐man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate

Comparative embryotoxicity of different antimalarial peroxides: In vitro study using the rat whole embryo culture model (WEC)

Macrolide Therapy of Group A Streptococcal Pharyngitis: 10 Days of Macrolide Therapy (Clarithromycin) Is More Effective in Streptococcal Eradication than 5 Days (Azithromycin)

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

A Randomized Trial of Clarithromycin as Prophylaxis against Disseminated Mycobacterium avium Complex Infection in Patients with Advanced Acquired Immunodeficiency Syndrome

Clarithromycin Resistance and Susceptibility Patterns of Mycobacterium avium Strains Isolated During Prophylaxis for Disseminated Infection in Patients with AIDS

Clarithromycin and ethambutol with or without clofazimine for the treatment of bacteremic Mycobacterium avium complex disease in patients with HIV infection

Medicines for Malaria Venture new developments in antimalarials

Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

Steady-State Pharmacokinetics and Electrocardiographic Pharmacodynamics of Clarithromycin and Loratadine after Individual or Concomitant Administration

Ketolide ABT-773 is active against Toxoplasma gondii

Overview of the tolerability profile of clarithromycin in preclinical and clinical trials

Overview of the safety profile of clarithromycin suspension in pediatric patients

Ancillary benefits of Mycobacterium avium-intracellulare complex prophylaxis with clarithromycin in HIV-infected patients

A Randomized, Double-Blind Phase 2 Study Comparing the Efficacy and Safety of an Oral Fusidic Acid Loading-Dose Regimen to Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections: Fusidic Acid Enters the United States

Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults

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