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Synthesis of and Biological Study of 7-Benzyl-3-aminobenzimidazo[3,2- a]quinolinium Chloride (ABQ-48: NSC D-763307) and 7-benzyl-3- nitrobenzimidazo[3,2-a]quinolinium Chloride (NBQ 48: NSC D-763303)

Current bioactive compounds, 2015-02, Vol.10 (4), p.286-291

2015

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Abstract 5602: Markers of hypoxic cells: Testing a pre-clinical detection assay

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5602-5602

2023

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Abstract 4774: Hypoxic bio-reduction of novel NBQ48 in treated tumor cells and the activity of cytochrome P450 reductase

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4774-4774

2016

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Novel NBQ-48 as marker of hypoxic cells in 2D and 3D colon cancer cells

Journal of Cancer Prevention & Current Research, 2020-01, Vol.11 (1), p.13-18

2020

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Abstract 1586: Toxicity screening, apoptosis hallmark events and nitro reduction of novel quinolinium salts (BQS) on lymphoma cells

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1586-1586

2014

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Abstract 4474: Cellular effects of fluorescent quinolinium drugs on normal lymphoblast and A431 carcinoma cells

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4474-4474

2011

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Toxicity and Apoptosis Related Effects of Benzimidazo [3,2-α] Quinolinium Salts Upon Human Lymphoma Cells

The open medicinal chemistry journal, 2017-06, Vol.11 (1), p.54-65

2017

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Regioselective photocyclization of (e)-2-(2,3,6-trichlorostyryl)-benzothiazole and synthesis of 3,4-dichloro- and 4-chlorobenzothiazolo[3,2-α]quinolinium chlorides: A synthetic and theoretical study

Journal of heterocyclic chemistry, 2008-09, Vol.45 (5), p.1255-1264

2008

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Role of the Nitro Functionality in the DNA Binding of 3-Nitro-10-methylbenzothiazolo[3,2-a]quinolinium Chloride

Chemical research in toxicology, 2008-09, Vol.21 (9), p.1706-1715

2008

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Novel Nitrobenzazolo[3,2- a ]quinolinium Salts Induce Cell Death through a Mechanism Involving DNA Damage, Cell Cycle Changes, and Mitochondrial Permeabilization

Open journal of apoptosis, 2013-04, Vol.2 (2), p.13-22

2013

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Comparison of the nucleic acid covalent binding capacity of two nitro-substituted benzazolo[3,2- a]quinolinium salts upon enzymatic reduction

Toxicology in vitro, 2007-09, Vol.21 (6), p.1155-1164

2007

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Reductive activation and thiol reactivity of benzazolo[3,2- a]quinolinium salts

Toxicology (Amsterdam), 2004-07, Vol.199 (2), p.87-96

2004

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Immunomodulatory Response Triggered by the Alkaloids, 3-Amino- 7-Benzylbenzimidazo[3,2-a] Quinolinium Chloride (ABQ-48) and 3-Nitro- 7-Benzylbenzimidazo[3,2-a] Quinolinium Chloride (NBQ-48)

Journal of Cancer Research and Therapeutic Oncology, 2015-05

Zayas, Beatriz

2015

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Cytotoxic anionic tribromo platinum(II) complexes containing benzothiazole and benzoxazole donors: synthesis, characterization, and structure-activity correlation

Inorganica Chimica Acta, 1998-04, Vol.271 (1), p.137-144

1998

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Solvolytic studies of tricyclo[4.2.0.02,4]octan-5-yl derivatives. Effect of cyclopropane and cyclobutane orbital alignments on reactivity and proclivity for rearrangement

Journal of the American Chemical Society, 1974-07, Vol.96 (15), p.4892-4901

1974

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Synthesis and complete 1 H and 13 C assignments of thiazolo[3,2‐ a ]quinolinium derivatives

Journal of heterocyclic chemistry, 1999-07, Vol.36 (4), p.937-942

1999

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Synthesis and complete 1H and 13C assignments of thiazolo[3,2-a]quinolinium derivatives

Journal of heterocyclic chemistry, 1999-07, Vol.36 (4), p.937-942

1999

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Photochemical transformations of selected 3-cycloheptenone derivatives

Journal of the American Chemical Society, 1968-09, Vol.90 (19), p.5153-5159

1968

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DNA binding-independent anti-proliferative action of benzazolo[3,2-alpha]quinolinium DNA intercalators

Molecular and cellular biochemistry, 1997-12, Vol.177 (1-2), p.69-77

1997

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Inhibition of human topoisomerase II by anti-neoplastic benzazolo[3,2-alpha]quinolinium chlorides

Molecular and cellular biochemistry, 1998-01, Vol.178 (1-2), p.203-212

1998

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Electrochemical and electron spin resonance studies of selected benzazolo[3,2-a]quinolinium salts

Journal of heterocyclic chemistry, 1999-07, Vol.36 (4), p.943-947

1999

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Synthesis and characterization of new platinum(II) complexes containing thiazole and imidazole donors III. Dichlorobis(styrylbenzazole)platinum(II) complexes

Inorganica Chimica Acta, 1992, Vol.191 (1), p.131-139

1992

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N-(o-Tolyl)-2-bromo-4,5-dimethoxybenzamide

Acta crystallographica. Section C, Crystal structure communications, 1998-01, Vol.54 (1), p.69-71

1998

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(E,Z)-2-(2-Chloro-5-nitrostyryl)-1-(1-propenyl)benzimidazole

Acta crystallographica. Section C, Crystal structure communications, 1997-07, Vol.53 (7), p.907-909

1997

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Reductive activation of benzazolo[3,2-a]-quinolinium chlorides

Free radical biology & medicine, 1993-07, Vol.15 (1), p.49-56

1993

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Synthesis of and Biological Study of 7-Benzyl-3-aminobenzimidazo[3,2- a]quinolinium Chloride (ABQ-48: NSC D-763307) and 7-benzyl-3- nitrobenzimidazo[3,2-a]quinolinium Chloride (NBQ 48: NSC D-763303)

Abstract 5602: Markers of hypoxic cells: Testing a pre-clinical detection assay

Abstract 4774: Hypoxic bio-reduction of novel NBQ48 in treated tumor cells and the activity of cytochrome P450 reductase

Novel NBQ-48 as marker of hypoxic cells in 2D and 3D colon cancer cells

Abstract 1586: Toxicity screening, apoptosis hallmark events and nitro reduction of novel quinolinium salts (BQS) on lymphoma cells

Abstract 4474: Cellular effects of fluorescent quinolinium drugs on normal lymphoblast and A431 carcinoma cells

Toxicity and Apoptosis Related Effects of Benzimidazo [3,2-α] Quinolinium Salts Upon Human Lymphoma Cells

Regioselective photocyclization of (e)-2-(2,3,6-trichlorostyryl)-benzothiazole and synthesis of 3,4-dichloro- and 4-chlorobenzothiazolo[3,2-α]quinolinium chlorides: A synthetic and theoretical study

Role of the Nitro Functionality in the DNA Binding of 3-Nitro-10-methylbenzothiazolo[3,2-a]quinolinium Chloride

Novel Nitrobenzazolo[3,2- a ]quinolinium Salts Induce Cell Death through a Mechanism Involving DNA Damage, Cell Cycle Changes, and Mitochondrial Permeabilization

Comparison of the nucleic acid covalent binding capacity of two nitro-substituted benzazolo[3,2- a]quinolinium salts upon enzymatic reduction

Reductive activation and thiol reactivity of benzazolo[3,2- a]quinolinium salts

Immunomodulatory Response Triggered by the Alkaloids, 3-Amino- 7-Benzylbenzimidazo[3,2-a] Quinolinium Chloride (ABQ-48) and 3-Nitro- 7-Benzylbenzimidazo[3,2-a] Quinolinium Chloride (NBQ-48)

Cytotoxic anionic tribromo platinum(II) complexes containing benzothiazole and benzoxazole donors: synthesis, characterization, and structure-activity correlation

Solvolytic studies of tricyclo[4.2.0.02,4]octan-5-yl derivatives. Effect of cyclopropane and cyclobutane orbital alignments on reactivity and proclivity for rearrangement

Synthesis and complete 1 H and 13 C assignments of thiazolo[3,2‐ a ]quinolinium derivatives

Synthesis and complete 1H and 13C assignments of thiazolo[3,2-a]quinolinium derivatives

Photochemical transformations of selected 3-cycloheptenone derivatives

DNA binding-independent anti-proliferative action of benzazolo[3,2-alpha]quinolinium DNA intercalators

Inhibition of human topoisomerase II by anti-neoplastic benzazolo[3,2-alpha]quinolinium chlorides

Electrochemical and electron spin resonance studies of selected benzazolo[3,2-a]quinolinium salts

Synthesis and characterization of new platinum(II) complexes containing thiazole and imidazole donors III. Dichlorobis(styrylbenzazole)platinum(II) complexes

N-(o-Tolyl)-2-bromo-4,5-dimethoxybenzamide

(E,Z)-2-(2-Chloro-5-nitrostyryl)-1-(1-propenyl)benzimidazole

Reductive activation of benzazolo[3,2-a]-quinolinium chlorides

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