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LRRK2 inhibition attenuates microglial inflammatory responses

The Journal of neuroscience, 2012-02, Vol.32 (5), p.1602-1611

2012

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Social Isolation Exacerbates Schizophrenia-Like Phenotypes via Oxidative Stress in Cortical Interneurons

Biological psychiatry (1969), 2013-05, Vol.73 (10), p.1024-1034

2013

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The NRF2-Dependent Transcriptional Regulation of Antioxidant Defense Pathways: Relevance for Cell Type-Specific Vulnerability to Neurodegeneration and Therapeutic Intervention

Antioxidants, 2021-12, Vol.11 (1), p.8

2021

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Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala

Neurobiology of disease, 2024-09, Vol.199, p.106595, Article 106595

2024

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Molecular Mechanisms Underlying Synaptic and Axon Degeneration in Parkinson's Disease

Frontiers in cellular neuroscience, 2021-03, Vol.15, p.626128-626128

2021

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Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia

Frontiers in behavioral neuroscience, 2013-09, Vol.7, p.116

2013

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Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Biochemical journal, 2013-07, Vol.453 (1), p.101-113

2013

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Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents

Journal of comparative neurology (1911), 2014-08, Vol.522 (11), p.2465-2480

2014

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Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice

Neurobiology of disease, 2021-10, Vol.158, p.105454-105454, Article 105454

2021

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Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability

Nature communications, 2016-11, Vol.7 (1), p.13470-13470, Article 13470

2016

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Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities

Cells (Basel, Switzerland), 2021-02, Vol.10 (2), p.352

2021

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Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1α

PloS one, 2012-08, Vol.7 (8), p.e42878-e42878

2012

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Transcriptional dysregulation causes altered modulation of inhibition by haloperidol

Neuropharmacology, 2016-12, Vol.111, p.304-313

2016

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Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality

Brain communications, 2021-01, Vol.3 (3), p.fcab208-fcab208

2021

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Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations

Acta neuropathologica communications, 2023-04, Vol.11 (1), p.70-70, Article 70

2023

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Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1

Antioxidants, 2022-09, Vol.11 (10), p.1888

2022

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Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2.1 Channels

Neuroscience, 2023-03, Vol.513, p.38-53

2023

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PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model

Journal of neurophysiology, 2022-01, Vol.127 (1), p.86-98

2022

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LRRK2 secretion in exosomes is regulated by 14-3-3

Human molecular genetics, 2013-12, Vol.22 (24), p.4988-5000

2013

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High‐Fat and High‐Sucrose Diets Impair Time‐of‐Day Differences in Spatial Working Memory of Male Mice

Obesity (Silver Spring, Md.), 2020-12, Vol.28 (12), p.2347-2356

2020

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Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus

The Journal of neuroscience, 2015-11, Vol.35 (46), p.15276-15290

2015

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PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons

The Journal of neuroscience, 2014-10, Vol.34 (43), p.14375-14387

2014

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PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons

Neurochemistry international, 2021-09, Vol.148, p.105077, Article 105077

2021

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Neuronal Inactivation of Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Protects Mice from Diet-induced Obesity and Leads to Degenerative Lesions

The Journal of biological chemistry, 2010-12, Vol.285 (50), p.39087-39095

2010

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Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment

The Journal of neuroscience, 2018-03, Vol.38 (13), p.3273-3286

2018

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LRRK2 inhibition attenuates microglial inflammatory responses

Social Isolation Exacerbates Schizophrenia-Like Phenotypes via Oxidative Stress in Cortical Interneurons

The NRF2-Dependent Transcriptional Regulation of Antioxidant Defense Pathways: Relevance for Cell Type-Specific Vulnerability to Neurodegeneration and Therapeutic Intervention

Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala

Molecular Mechanisms Underlying Synaptic and Axon Degeneration in Parkinson's Disease

Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia

Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents

Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice

Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability

Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities

Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1α

Transcriptional dysregulation causes altered modulation of inhibition by haloperidol

Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality

Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations

Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1

Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2.1 Channels

PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model

LRRK2 secretion in exosomes is regulated by 14-3-3

High‐Fat and High‐Sucrose Diets Impair Time‐of‐Day Differences in Spatial Working Memory of Male Mice

Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus

PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons

PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons

Neuronal Inactivation of Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Protects Mice from Diet-induced Obesity and Leads to Degenerative Lesions

Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment

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