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Synthesis of 5-Fluoro N-Acetylglucosamine Glycosides and Pyrophosphates via Epoxide Fluoridolysis: Versatile Reagents for the Study of Glycoconjugate Biochemistry

Journal of the American Chemical Society, 2002-08, Vol.124 (34), p.10036-10053

2002

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Prodrug Forms of N-[(4-Deoxy-4-amino-10-methyl)pteroyl]glutamate-γ-[ψP(O)(OH)]-glutarate, a Potent Inhibitor of Folylpoly-γ-glutamate Synthetase: Synthesis and Hydrolytic Stability

Journal of medicinal chemistry, 2006-01, Vol.49 (2), p.770-788

2006

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Synthesis of p-Aminophenyl Aryl H-Phosphinic Acids and Esters via Cross-Coupling Reactions: Elaboration to Phosphinic Acid Pseudopeptide Analogues of Pteroyl Glutamic Acid and Related Antifolates

Journal of organic chemistry, 2007-07, Vol.72 (15), p.5748-5758

2007

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Electrophilic Fluorination of Pyroglutamic Acid Derivatives: Application of Substrate-Dependent Reactivity and Diastereoselectivity to the Synthesis of Optically Active 4-Fluoroglutamic Acids

Journal of organic chemistry, 2001-12, Vol.66 (26), p.8831-8842

2001

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UDP-(5F)-GlcNAc Acts as a Slow-Binding Inhibitor of MshA, a Retaining Glycosyltransferase

Journal of the American Chemical Society, 2010-05, Vol.132 (19), p.6626-6627

2010

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A Stereoselective Synthesis of Phosphinic Acid Phosphapeptides Corresponding to Glutamyl-γ-glutamate and Incorporation into Potent Inhibitors of Folylpoly-γ-glutamyl Synthetase

Journal of organic chemistry, 2005-08, Vol.70 (17), p.6757-6774

2005

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The Chemistry of Phosphapeptides: Investigations on the Synthesis of Phosphonamidate, Phosphonate, and Phosphinate Analogs of Glutamyl-.gamma.-glutamate

Journal of organic chemistry, 1994-12, Vol.59 (25), p.7625-7634

1994

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ATP-dependent ligases in trypanothione biosynthesis - kinetics of catalysis and inhibition by phosphinic acid pseudopeptides

European journal of biochemistry, 2008-11, Vol.275 (21), p.5408-5421

2008

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Characterisation of the bifunctional dihydrofolate synthase–folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition

Molecular and biochemical parasitology, 2010-07, Vol.172 (1), p.41-51

2010

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A Cell Cycle-Regulated Adenine DNA Methyltransferase from Caulobacter crescentus Processively Methylates GANTC Sites on Hemimethylated DNA

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (6), p.2874-2879

1998

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Concentration-Dependent Processivity of Multiple Glutamate Ligations Catalyzed by Folylpoly-γ-glutamate Synthetase

Biochemistry (Easton), 2008-08, Vol.47 (34), p.9040-9050

2008

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Synthesis of Isopeptide Epoxide Peptidomimetics

Journal of organic chemistry, 2009-01, Vol.74 (2), p.617-627

2009

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Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase

The EMBO journal, 2006-12, Vol.25 (24), p.5970-5982

2006

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γ-Glutamyl Hydrolase: Kinetic Characterization of Isopeptide Hydrolysis Using Fluorogenic Substrates

Biochemistry (Easton), 2008-01, Vol.47 (4), p.1228-1239

2008

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Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate

Archives of biochemistry and biophysics, 2009-08, Vol.488 (2), p.140-145

2009

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Phosphinic Acid Pseudopeptides Analogous to Glutamyl-γ-glutamate: Synthesis and Coupling to Pteroyl Azides Leads to Potent Inhibitors of Folylpoly-γ-glutamate Synthetase

Journal of organic chemistry, 2001-07, Vol.66 (15), p.5146-5154

2001

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Glycosyltransferase Mechanisms: Impact of a 5-Fluoro Substituent in Acceptor and Donor Substrates on Catalysis

Biochemistry (Easton), 2007-10, Vol.46 (41), p.11630-11638

2007

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Investigations on New Strategies for the Facile Synthesis of Polyfunctionalized Phosphinates: Phosphinopeptide Analogues of Glutathionylspermidine

Journal of organic chemistry, 1998-02, Vol.63 (3), p.502-509

1998

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Enzyme-catalyzed glycosylation of peptides using a synthetic lipid disaccharide substrate

Journal of organic chemistry, 1992-07, Vol.57 (15), p.4126-4135

1992

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Synthesis of l-4,4-Difluoroglutamic Acid via Electrophilic Difluorination of a Lactam

Organic letters, 1999-12, Vol.1 (13), p.2105-2107

1999

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Synthesis and Biochemical Evaluation of Adenosylspermidine, a Nucleoside-Polyamine Adduct Inhibitor of Spermidine Synthase

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2714-2727

1995

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Regioselective Synthesis of α-Methyl 2-Methyleneglutarate via a Novel Lactonization−Elimination Rearrangement

Journal of organic chemistry, 2006-01, Vol.71 (1), p.372-374

2006

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Synthesis of (6R)- and (6S)-5,10-dideazatetrahydrofolate oligo-gamma-glutamates: kinetics of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetase

Organic & biomolecular chemistry, 2005-09, Vol.3 (18), p.3388-3398

2005

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The Chemistry of Phosphapeptides: Formation of Functionalized Phosphonochloridates under Mild Conditions and Their Reaction with Alcohols and Amines

Journal of organic chemistry, 1994-12, Vol.59 (25), p.7616-7624

1994

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A Biotin Capture Assay for Oligosaccharyltransferase

Analytical biochemistry, 2002-07, Vol.306 (2), p.328-335

2002

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Synthesis of 5-Fluoro N-Acetylglucosamine Glycosides and Pyrophosphates via Epoxide Fluoridolysis: Versatile Reagents for the Study of Glycoconjugate Biochemistry

Prodrug Forms of N-[(4-Deoxy-4-amino-10-methyl)pteroyl]glutamate-γ-[ψP(O)(OH)]-glutarate, a Potent Inhibitor of Folylpoly-γ-glutamate Synthetase: Synthesis and Hydrolytic Stability

Synthesis of p-Aminophenyl Aryl H-Phosphinic Acids and Esters via Cross-Coupling Reactions: Elaboration to Phosphinic Acid Pseudopeptide Analogues of Pteroyl Glutamic Acid and Related Antifolates

Electrophilic Fluorination of Pyroglutamic Acid Derivatives: Application of Substrate-Dependent Reactivity and Diastereoselectivity to the Synthesis of Optically Active 4-Fluoroglutamic Acids

UDP-(5F)-GlcNAc Acts as a Slow-Binding Inhibitor of MshA, a Retaining Glycosyltransferase

A Stereoselective Synthesis of Phosphinic Acid Phosphapeptides Corresponding to Glutamyl-γ-glutamate and Incorporation into Potent Inhibitors of Folylpoly-γ-glutamyl Synthetase

The Chemistry of Phosphapeptides: Investigations on the Synthesis of Phosphonamidate, Phosphonate, and Phosphinate Analogs of Glutamyl-.gamma.-glutamate

ATP-dependent ligases in trypanothione biosynthesis - kinetics of catalysis and inhibition by phosphinic acid pseudopeptides

Characterisation of the bifunctional dihydrofolate synthase–folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition

A Cell Cycle-Regulated Adenine DNA Methyltransferase from Caulobacter crescentus Processively Methylates GANTC Sites on Hemimethylated DNA

Concentration-Dependent Processivity of Multiple Glutamate Ligations Catalyzed by Folylpoly-γ-glutamate Synthetase

Synthesis of Isopeptide Epoxide Peptidomimetics

Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase

γ-Glutamyl Hydrolase: Kinetic Characterization of Isopeptide Hydrolysis Using Fluorogenic Substrates

Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate

Phosphinic Acid Pseudopeptides Analogous to Glutamyl-γ-glutamate: Synthesis and Coupling to Pteroyl Azides Leads to Potent Inhibitors of Folylpoly-γ-glutamate Synthetase

Glycosyltransferase Mechanisms: Impact of a 5-Fluoro Substituent in Acceptor and Donor Substrates on Catalysis

Investigations on New Strategies for the Facile Synthesis of Polyfunctionalized Phosphinates: Phosphinopeptide Analogues of Glutathionylspermidine

Enzyme-catalyzed glycosylation of peptides using a synthetic lipid disaccharide substrate

Synthesis of l-4,4-Difluoroglutamic Acid via Electrophilic Difluorination of a Lactam

Synthesis and Biochemical Evaluation of Adenosylspermidine, a Nucleoside-Polyamine Adduct Inhibitor of Spermidine Synthase

Regioselective Synthesis of α-Methyl 2-Methyleneglutarate via a Novel Lactonization−Elimination Rearrangement

Synthesis of (6R)- and (6S)-5,10-dideazatetrahydrofolate oligo-gamma-glutamates: kinetics of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetase

The Chemistry of Phosphapeptides: Formation of Functionalized Phosphonochloridates under Mild Conditions and Their Reaction with Alcohols and Amines

A Biotin Capture Assay for Oligosaccharyltransferase

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