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Total Synthesis of Bryostatin 1

Journal of the American Chemical Society, 2011-02, Vol.133 (4), p.744-747

2011

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Pyran Annulation: Asymmetric Synthesis of 2,6-Disubstituted-4-methylene Tetrahydropyrans

Organic letters, 2002-04, Vol.4 (7), p.1189-1192

2002

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Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and in vitro evaluation against Cryptococcus spp

Bioorganic & medicinal chemistry letters, 2019-12, Vol.29 (23), p.126713-126713, Article 126713

2019

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A new family of H3 receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1490-1494

2008

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A calcineurin antifungal strategy with analogs of FK506

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2465-2471

2017

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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4′-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.71-75

2012

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Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5603

2009

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Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H3 Receptor Inverse Agonist Activity

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5603-5611

2009

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Novel H3 receptor antagonists with improved pharmacokinetic profiles

Bioorganic & medicinal chemistry letters, 2008-07, Vol.18 (14), p.4133-4136

2008

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Asymmetric Total Synthesis of Rhizoxin D

Angewandte Chemie International Edition, 2001-01, Vol.40 (1), p.231-234

2001

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Synthesis of ansa-Titanocenes from 1,2-Bis(2-indenyl)ethane and Structural Comparisons in the Catalytic Epoxidation of Unfunctionalized Alkenes

Organometallics, 1995-08, Vol.14 (8), p.3732-3740

1995

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A new family of H 3 receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1490-1494

2008

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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4&; prime; -(3-methoxypropylsulfonyl)biphenyl-4-yl)e thyl)-2-methylpyrrolidine (APD916)

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.71-75

2012

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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine (APD916)

Bioorganic & medicinal chemistry letters, 2012, Vol.22 (1), p.71-75

2012

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Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H 3 Receptor Inverse Agonist Activity

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5603-5611

2009

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Novel H 3 receptor antagonists with improved pharmacokinetic profiles

Bioorganic & medicinal chemistry letters, 2008-07, Vol.18 (14), p.4133-4136

2008

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Asymmetric Total Synthesis of Rhizoxin D Financial support has been provided by the National Institutes of Health (through grant GM-28961) and by Pfizer, Inc

Angewandte Chemie International Edition, 2001-01, Vol.40 (1), p.231-234

2001

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Novel H sub(3) receptor antagonists with improved pharmacokinetic profiles

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4133-4136

2008

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A new family of H sub(3) receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1490-1494

2008

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Asymmetric Total Synthesis of Rhizoxin D

Angewandte Chemie, 2001-01, Vol.113 (1), p.237-240

2001

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Pyran Annulation: Asymmetric Synthesis of 2,6-Disubstituted-4-methylene Tetrahydropyrans

ChemInform, 2002-09, Vol.33 (35), p.132-132

2002

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ChemInform Abstract: Asymmetric Total Synthesis of Rhizoxin D

ChemInform, 2001-04, Vol.32 (15), p.no-no

2001

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Asymmetric Total Synthesis of Rhizoxin D

Angewandte Chemie, 2001-01, Vol.113 (1), p.237-240

2001

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APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

Antimicrobial agents and chemotherapy, 2019-02, Vol.63 (2)

2019

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In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

Antimicrobial agents and chemotherapy, 2018-08, Vol.62 (8)

2018

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Total Synthesis of Bryostatin 1

Pyran Annulation: Asymmetric Synthesis of 2,6-Disubstituted-4-methylene Tetrahydropyrans

Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and in vitro evaluation against Cryptococcus spp

A new family of H3 receptor antagonists based on the natural product Conessine

A calcineurin antifungal strategy with analogs of FK506

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4′-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)

Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity

Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H3 Receptor Inverse Agonist Activity

Novel H3 receptor antagonists with improved pharmacokinetic profiles

Asymmetric Total Synthesis of Rhizoxin D

Synthesis of ansa-Titanocenes from 1,2-Bis(2-indenyl)ethane and Structural Comparisons in the Catalytic Epoxidation of Unfunctionalized Alkenes

A new family of H 3 receptor antagonists based on the natural product Conessine

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4&; prime; -(3-methoxypropylsulfonyl)biphenyl-4-yl)e thyl)-2-methylpyrrolidine (APD916)

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine (APD916)

Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H 3 Receptor Inverse Agonist Activity

Novel H 3 receptor antagonists with improved pharmacokinetic profiles

Asymmetric Total Synthesis of Rhizoxin D Financial support has been provided by the National Institutes of Health (through grant GM-28961) and by Pfizer, Inc

Novel H sub(3) receptor antagonists with improved pharmacokinetic profiles

A new family of H sub(3) receptor antagonists based on the natural product Conessine

Asymmetric Total Synthesis of Rhizoxin D

Pyran Annulation: Asymmetric Synthesis of 2,6-Disubstituted-4-methylene Tetrahydropyrans

ChemInform Abstract: Asymmetric Total Synthesis of Rhizoxin D

Asymmetric Total Synthesis of Rhizoxin D

APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

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