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Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

Nature (London), 2016-01, Vol.529 (7587), p.541-545

2016

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Structural Basis of Outstanding Multivalent Effects in Jack Bean α‐Mannosidase Inhibition

Angewandte Chemie International Edition, 2018-07, Vol.57 (27), p.8002-8006

International ed. in English, 2018

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Lipid exchange in crystal-confined fatty acid binding proteins: X-ray evidence and molecular dynamics explanation

Proteins, structure, function, and bioinformatics, 2023-11, Vol.91 (11), p.1525-1534

2023

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Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

Chemistry : a European journal, 2016-04, Vol.22 (15), p.5151-5155

2016

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Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5

Proteins, structure, function, and bioinformatics, 2016-01, Vol.84 (1), p.129-142

2016

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Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design

Acta crystallographica. Section D, Biological crystallography., 2014-03, Vol.70 (3), p.889-903

2014

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Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface

Journal of molecular recognition, 2011-07, Vol.24 (4), p.724-732

2011

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Quantitative fragmentomics allow affinity mapping of interactomes

Nature communications, 2022-09, Vol.13 (1), p.5472-5472, Article 5472

2022

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Author Correction: Quantitative fragmentomics allow affinity mapping of interactomes

Nature communications, 2022-12, Vol.13 (1), p.7555-7555, Article 7555

2022

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X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain

PloS one, 2016-04, Vol.11 (4), p.e0154190-e0154190

2016

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Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase

European journal of medicinal chemistry, 2018-05, Vol.152, p.160-174

2018

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Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.695-710

2018

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New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM

Acta crystallographica. Section D, Biological crystallography., 2015-07, Vol.71 (7), p.1455-1470

2015

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Discovery of (R)‑2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2568-2580

2013

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Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase

PloS one, 2015-07, Vol.10 (7), p.e0134506

2015

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Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (6), p.1844-1848

2008

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Crystal packing modifies ligand binding affinity: The case of aldose reductase

Proteins, structure, function, and bioinformatics, 2012-11, Vol.80 (11), p.2552-2561

2012

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Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

ChemMedChem, 2015-12, Vol.10 (12), p.1989-2003

2015

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X-ray-induced deterioration of disulfide bridges at atomic resolution

Acta crystallographica. Section D, Biological crystallography., 2010-10, Vol.66 (10), p.1075-1091

2010

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Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders

Analytical biochemistry, 2012-02, Vol.421 (2), p.417-427

2012

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Cover Picture: Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10 (ChemMedChem 12/2015)

ChemMedChem, 2015-12, Vol.10 (12), p.1941-1941

2015

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Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex

Journal of medicinal chemistry, 2005-09, Vol.48 (18), p.5659-5665

2005

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Structural Basis of Outstanding Multivalent Effects in Jack Bean α‐Mannosidase Inhibition

Angewandte Chemie, 2018-07, Vol.130 (27), p.8134-8138

2018

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Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography

Acta crystallographica. Section D, Biological crystallography., 2014-12, Vol.70 (12), p.3266-3272

2014

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Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger

Acta crystallographica. Section D, Biological crystallography., 2012-09, Vol.68 (9), p.1098-1107

2012

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Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

Structural Basis of Outstanding Multivalent Effects in Jack Bean α‐Mannosidase Inhibition

Lipid exchange in crystal-confined fatty acid binding proteins: X-ray evidence and molecular dynamics explanation

Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5

Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design

Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface

Quantitative fragmentomics allow affinity mapping of interactomes

Author Correction: Quantitative fragmentomics allow affinity mapping of interactomes

X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain

Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM

Discovery of (R)‑2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

Crystal packing modifies ligand binding affinity: The case of aldose reductase

Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

X-ray-induced deterioration of disulfide bridges at atomic resolution

Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders

Cover Picture: Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10 (ChemMedChem 12/2015)

Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex

Structural Basis of Outstanding Multivalent Effects in Jack Bean α‐Mannosidase Inhibition

Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography

Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger

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