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T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation

Clinical immunology (Orlando, Fla.), 2013-12, Vol.149 (3), p.534-555

2013

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Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis

Scientific reports, 2021-10, Vol.11 (1), p.20827-17, Article 20827

2021

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Tregitope update: Mechanism of action parallels IVIg

Autoimmunity reviews, 2013-01, Vol.12 (3), p.436-443

2013

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Metabolic adverse events associated with systemic corticosteroid therapy—a systematic review and meta-analysis

BMJ open, 2022-12, Vol.12 (12), p.e061476-e061476

2022

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NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

Annual review of immunology, 1999-01, Vol.17 (1), p.189-220

1999

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In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

Journal of clinical immunology, 2013-01, Vol.33 (Suppl 1), p.43-49

2013

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Tregitope Peptides: The Active Pharmaceutical Ingredient of IVIG?

Clinical & developmental immunology, 2013-01, Vol.2013 (2013), p.1-6

2013

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Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes

Molecular therapy, 2013-09, Vol.21 (9), p.1727-1737

2013

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Interferon-α /β Inhibition of Interleukin 12 and interferon-γ Production in vitro and Endogenously during Viral Infection

Proceedings of the National Academy of Sciences - PNAS, 1997-01, Vol.94 (2), p.634-639

1997

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Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes

Journal of diabetes research, 2013-01, Vol.2013 (2013), p.1-17

2013

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Human T Cells Armed with Her2/neu Bispecific Antibodies Divide, Are Cytotoxic, and Secrete Cytokines with Repeated Stimulation

Clinical cancer research, 2006-01, Vol.12 (2), p.569-576

2006

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Interferon α/β-mediated inhibition and promotion of interferon γ: STAT1 resolves a paradox

Nature immunology, 2000-07, Vol.1 (1), p.70-76

2000

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Determinants of immunogenic response to protein therapeutics

Biologicals, 2012-09, Vol.40 (5), p.364-368

2012

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Complementary Adhesion Molecules Promote Neutrophil- Kupffer Cell Interaction and the Elimination of Bacteria Taken Up by the Liver

The Journal of immunology (1950), 2002-01, Vol.168 (1), p.308-315

2002

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Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

Human vaccines & immunotherapeutics, 2012-10, Vol.8 (10), p.1459-1464

2012

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Stat3 Cleavage by Caspases: IMPACT ON FULL-LENGTH Stat3 EXPRESSION, FRAGMENT FORMATION, AND TRANSCRIPTIONAL ACTIVITY

The Journal of biological chemistry, 2006-06, Vol.281 (26), p.17707-17717

2006

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In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

Journal of clinical immunology, 2013-01, Vol.33 (S1), p.43-49

2013

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Abstract P176: Metabolic Side Effects Of Systemic Corticosteroids - A Systematic Review

Hypertension (Dallas, Tex. 1979), 2020-09, Vol.76 (Suppl_1)

2020

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Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis

American journal of respiratory and critical care medicine, 2022-12, Vol.206 (12), p.1463-1479

2022

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Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer

Cancer chemotherapy and pharmacology, 2004-09, Vol.54 (3), p.249-258

2004

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Tregitope: Immunomodulation Powerhouse

Human immunology, 2014-12, Vol.75 (12), p.1139-1146

2014

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Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial

Clinical and experimental allergy, 2022-07, Vol.52 (7), p.859-867

2022

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JAK-Mediated Signaling Inhibits Fas Ligand-Induced Apoptosis Independent of De Novo Protein Synthesis

The Journal of immunology (1950), 2005-01, Vol.174 (1), p.320-327

2005

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Tregitopes: The active ingredient in IVIG-mediated tolerance induction? (P5224)

The Journal of immunology (1950), 2013-05, Vol.190 (1_Supplement), p.67-67.7

2013

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Improved GAA activity in tregitope-treated pompe disease: preclinical studies (TECH1P.864)

The Journal of immunology (1950), 2014-05, Vol.192 (1_Supplement), p.69-69.32

2014

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T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation

Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis

Tregitope update: Mechanism of action parallels IVIg

Metabolic adverse events associated with systemic corticosteroid therapy—a systematic review and meta-analysis

NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

Tregitope Peptides: The Active Pharmaceutical Ingredient of IVIG?

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes

Interferon-α /β Inhibition of Interleukin 12 and interferon-γ Production in vitro and Endogenously during Viral Infection

Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes

Human T Cells Armed with Her2/neu Bispecific Antibodies Divide, Are Cytotoxic, and Secrete Cytokines with Repeated Stimulation

Interferon α/β-mediated inhibition and promotion of interferon γ: STAT1 resolves a paradox

Determinants of immunogenic response to protein therapeutics

Complementary Adhesion Molecules Promote Neutrophil- Kupffer Cell Interaction and the Elimination of Bacteria Taken Up by the Liver

Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

Stat3 Cleavage by Caspases: IMPACT ON FULL-LENGTH Stat3 EXPRESSION, FRAGMENT FORMATION, AND TRANSCRIPTIONAL ACTIVITY

In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

Abstract P176: Metabolic Side Effects Of Systemic Corticosteroids - A Systematic Review

Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis

Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer

Tregitope: Immunomodulation Powerhouse

Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial

JAK-Mediated Signaling Inhibits Fas Ligand-Induced Apoptosis Independent of De Novo Protein Synthesis

Tregitopes: The active ingredient in IVIG-mediated tolerance induction? (P5224)

Improved GAA activity in tregitope-treated pompe disease: preclinical studies (TECH1P.864)

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