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Regulation of Angiotensin II Receptors on Ventricular Myocytes After Myocardial Infarction in Rats

Circulation research, 1993-06, Vol.72 (6), p.1149-1162

1993

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Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.353-356

2005

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Introduction

La Presse médicale (1983), 2015-11, Vol.44 Suppl 1, p.S1

Groupe d'étude MACVIA-LR

2015

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1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-indoles as novel 5-HT6 receptor ligands

Bioorganic & medicinal chemistry letters, 2004-11, Vol.14 (22), p.5499-5502

2004

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5-Fluoro-2-methyl- N -[4-(5 H -pyrrolo[2,1- c ]- [1,4]benzodiazepin-10(11 H )-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V 2 Receptors

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2442-2444

1998

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Structure–activity study of novel tricyclic benzazepine arginine vasopressin antagonists

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (13), p.2195-2198

2003

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5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]- [1,4]benzodiazepin-10(11H)-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V2 Receptors

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2442-2444

1998

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Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2603-2607

2004

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(4-Substituted-phenyl)-(5 H-10,11-dihydro-pyrrolo [2,1- c][1,4] benzodiazepin-10-yl)-methanone derivatives as vasopressin receptor modulators

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (22), p.5003-5006

2005

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6-isoxazolinyl and isoxazolidinyl substituted quinazolinones as angiotensin II receptor antagonists

Bioorganic & medicinal chemistry letters, 1994-07, Vol.4 (14), p.1703-1708

1994

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6-Substituted Quinazolinone Angiotensin II Receptor Antagonists

Bioorganic & medicinal chemistry letters, 1994-08, Vol.4 (15), p.1819-1824

1994

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2,3,6-Substituted quinazolinones as angiotensin II receptor antagonists

Bioorganic & medicinal chemistry letters, 1994-05, Vol.4 (9), p.1135-1140

1994

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Substituted 4H-pyrido[1,2-a]pyrimidin-4-one angiotensin II receptor antagonists

Bioorganic & medicinal chemistry letters, 1994-01, Vol.4 (1), p.183-188

1994

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New Generation Dopaminergic Agents. Part 8: Heterocyclic Bioisosteres that Exploit the 7-OH-2-(aminomethyl)chroman D 2 Template

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (3), p.271-274

2002

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Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a, 5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.1991-1994

2000

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Discovery of 5-Arylsulfonamido-3-(pyrrolidin-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT sub(6) Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.353-356

2005

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The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-aroyl-2,4,5,6-tetrahydropyrazolo-[3,4-d]thieno[3,2-b]azepines

Bioorganic & medicinal chemistry letters, 2000-04, Vol.10 (8), p.695-698

2000

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VPA-985, a nonpeptide orally active and selective vasopressin V2 receptor antagonist

Advances in experimental medicine and biology, 1998, Vol.449, p.439

1998

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New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans

Journal of medicinal chemistry, 1997-12, Vol.40 (26), p.4235-4256

1997

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New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D 2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans

Journal of medicinal chemistry, 1997-12, Vol.40 (26), p.4235-4256

1997

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5-fluoro-2-methyl-N-[5-(5 H-pyrrolo[2,1- c][1,4]benzodiazepine-10(11 H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (13), p.1737-1740

1999

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Hippocampal muscarinic receptor loss following trimethyl tin administration

Pharmacology, biochemistry and behavior, 1985, Vol.22 (1), p.147-151

1985

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4,10-Dihydro-5h-thieno[3,2-c][1]benzazepine derivatives and 9,10-dihydro-4h-thieno[2,3-c][1]benzazepine derivatives as orally active arginine vasopressin receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (13), p.1733-1736

1999

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New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D 2 template

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (17), p.2593-2598

1999

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New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D2 template

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (17), p.2593-2598

1999

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Regulation of Angiotensin II Receptors on Ventricular Myocytes After Myocardial Infarction in Rats

Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6 Receptor Agonists and Antagonists

Introduction

1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-indoles as novel 5-HT6 receptor ligands

5-Fluoro-2-methyl- N -[4-(5 H -pyrrolo[2,1- c ]- [1,4]benzodiazepin-10(11 H )-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V 2 Receptors

Structure–activity study of novel tricyclic benzazepine arginine vasopressin antagonists

5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]- [1,4]benzodiazepin-10(11H)-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V2 Receptors

Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor

(4-Substituted-phenyl)-(5 H-10,11-dihydro-pyrrolo [2,1- c][1,4] benzodiazepin-10-yl)-methanone derivatives as vasopressin receptor modulators

6-isoxazolinyl and isoxazolidinyl substituted quinazolinones as angiotensin II receptor antagonists

6-Substituted Quinazolinone Angiotensin II Receptor Antagonists

2,3,6-Substituted quinazolinones as angiotensin II receptor antagonists

Substituted 4H-pyrido[1,2-a]pyrimidin-4-one angiotensin II receptor antagonists

New Generation Dopaminergic Agents. Part 8: Heterocyclic Bioisosteres that Exploit the 7-OH-2-(aminomethyl)chroman D 2 Template

Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a, 5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

Discovery of 5-Arylsulfonamido-3-(pyrrolidin-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT sub(6) Receptor Agonists and Antagonists

The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-aroyl-2,4,5,6-tetrahydropyrazolo-[3,4-d]thieno[3,2-b]azepines

VPA-985, a nonpeptide orally active and selective vasopressin V2 receptor antagonist

New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans

New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D 2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans

5-fluoro-2-methyl-N-[5-(5 H-pyrrolo[2,1- c][1,4]benzodiazepine-10(11 H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists

Hippocampal muscarinic receptor loss following trimethyl tin administration

4,10-Dihydro-5h-thieno[3,2-c][1]benzazepine derivatives and 9,10-dihydro-4h-thieno[2,3-c][1]benzazepine derivatives as orally active arginine vasopressin receptor antagonists

New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D 2 template

New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D2 template

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